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Author Details

Lawrie W Powell
The University of Queensland
1962
379
72
PMIDPaper TitleJournal TitlePublished Year
35422339Arthritis Prediction of Advanced Hepatic Fibrosis in HFE Hemochromatosis.Mayo Clin Proc2022
32942924Arthropathy in hereditary haemochromatosis segregates with elevated erythrocyte mean corpuscular volume.Scand J Rheumatol2021
34282177Utility and limitations of Hepascore and transient elastography to detect advanced hepatic fibrosis in HFE hemochromatosis.Sci Rep2021
32745684Utility of Serum Biomarker Indices for Staging of Hepatic Fibrosis Before and After Venesection in Patients With Hemochromatosis Caused by Variants in HFE.Clin Gastroenterol Hepatol2021
31622736Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.Clin Gastroenterol Hepatol2020
32652459Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.Blood Cells Mol Dis2020
30340937Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests.Blood Cells Mol Dis2019
31882912Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis.Sci Rep2019
29600900Bilirubin acts as a multipotent guardian of cardiovascular integrity: more than just a radical idea.Am J Physiol Heart Circ Physiol2018
30145563Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.Ann Hepatol2018
29722188Haemochromatosis: a clinical update for the practising physician.Intern Med J2018
29743178Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease.Blood2018
27784128HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.J Gastroenterol Hepatol2017
28231420Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis.Liver Int2017
29195602Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial.Lancet Haematol2017
27936396GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.Blood Cells Mol Dis2017
28010035Reply.Hepatology2017
26845080Reply.Hepatology2016
26417986Reply.Hepatology2016
27004087Management of human factors engineering-associated hemochromatosis: A 2015 update.World J Hepatol2016
26975792Haemochromatosis.Lancet2016
25043645A career forged in iron.Hepatology2015
26270952Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron).BMJ Open2015
25839407Reduced mortality due to phlebotomy in moderately iron-loaded HFE haemochromatosis? The need for clinical trials.J Hepatol2015
25914125Reply: To PMID 25605615.Hepatology2015
25788196Recent advances in hemochromatosis: a 2015 update : a summary of proceedings of the 2014 conference held under the auspices of Hemochromatosis Australia.Hepatol Int2015
25605615Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.Hepatology2015
25311314Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.J Gastroenterol Hepatol2015
24037895Ductular reaction in hereditary hemochromatosis: the link between hepatocyte senescence and fibrosis progression.Hepatology2014
24830559Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation.Int J Mol Sci2014
24409064Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis.World J Gastroenterol2013
22020821Non-alcoholic fatty liver disease: is iron relevant?Hepatol Int2012
22422567Clinical cofactors and hepatic fibrosis in hereditary hemochromatosis: the role of diabetes mellitus.Hepatology2012
21452290Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases.Hepatology2011
21985049A comparison of self-reported and record-linked blood donation history in an Australian cohort.Transfusion2011
21901659Natural history and management of HFE-hemochromatosis.Semin Liver Dis2011
20099304HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.Hepatology2010
20814896A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis.Hepatology2010
20583211HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis.Hepatology2010
20179792The diagnosis and management of hereditary haemochromatosis.Clin Biochem Rev2010
19177571Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis.Hepatology2009
19669241The global burden of iron overload.Hepatol Int2009
19799707Overview: Liver disease and transplantation.J Gastroenterol Hepatol2009
19554541HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity.Hepatology2009
18199861Iron-overload-related disease in HFE hereditary hemochromatosis.N Engl J Med2008
19072377How much iron is too much?Expert Rev Gastroenterol Hepatol2008
18848943The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis.Gastroenterology2008
18316631Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis.Blood2008
18284459Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis.Intern Med J2008
17383046A novel mutation in ferroportin implicated in iron overload.J Hepatol2007
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Collaborators

Paul C Adams
Western University
Co-authored papers 20
James C Barton
University of Alabama at Birmingham
Co-authored papers 10
Kim M Summers
Mater Research Institute-University of Queensland, Translational Research Institute
Co-authored papers 9
Graham G Giles
Co-authored papers 8
Andrew D Clouston
University of Queensland
Co-authored papers 6
Nicholas G Martin
Co-authored papers 4
John B Whitfield
Co-authored papers 4
Sharon McDonnell
Newcastle upon Tyne NHS Foundation Trust
Co-authored papers 3
Amy Nisselle
Murdoch Children's Research Institute
Co-authored papers 3
Andrew C Heath
Co-authored papers 3
Zoltan H Endre
Prince of Wales Hospital and Clinical School, University of New South Wales
Co-authored papers 1
E Clayton
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 1
Sherman M Weissman
Co-authored papers 1
Wylie Burke
The Heart Institute, Cincinnati Children's Hospital Medical Center
Co-authored papers 1
Eric M Meslin
Dalla Lana School of Public Health, University of Toronto
Co-authored papers 1
Robert Williamson
Murdoch Children's Research Institute
Co-authored papers 1
Joseph L Witztum
Co-authored papers 1
Deborah A Nickerson
University of Washington
Co-authored papers 1
Francis S Collins
University of Michigan ann arbor
Co-authored papers 1
Elizabeth Thomson
Northrop Grumman Health Solutions
Co-authored papers 1
Ernest Beutler
The Scripps Research Institute
Co-authored papers 1
Victor R Gordeuk
Co-authored papers 1
Muin J Khoury
Centers for Disease Control and Prevention Atlanta GA USA.
Co-authored papers 1
Benjamin S Wilfond
University of Washington School of Medicine.
Co-authored papers 1
Jeffrey R Gruen
Yale Medical School
Co-authored papers 1
Arno G Motulsky
University of Washington
Co-authored papers 1
Melanie Bahlo
Co-authored papers 1
Allen Buchanan
University of Arizona
Co-authored papers 1
Bettina Meiser
Co-authored papers 1
Mary E Cogswell
Centers for Disease Control and Prevention
Co-authored papers 1
Release 1.2