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Author Details

Christopher A Miller
Washington University School of Medicine
2009
117
51
PMIDPaper TitleJournal TitlePublished Year
36055401Combined Kdm6a and Trp53 Deficiency Drives the Development of Squamous Cell Skin Cancer in Mice.J Invest Dermatol2023
37910143Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma.Cancer Res Commun2023
37160317Melanoma in a patient with DNMT3A overgrowth syndrome.Cold Spring Harb Mol Case Stud2023
37179276Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.Cancer Immunol Immunother2023
37339484Genomic landscape of TP53-mutated myeloid malignancies.Blood Adv2023
37400526Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival.Commun Biol2023
37027480Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.Sci Immunol2023
36480766Clonal Hematopoiesis and Risk of Incident Lung Cancer.J Clin Oncol2023
36711871Genomic landscape of <i>TP53</i> -mutated myeloid malignancies.medRxiv2023
34670359Tumor suppressor function of <i>WT1</i> in acute promyelocytic leukemia.Haematologica2022
35709710Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression.Blood Cancer Discov2022
35510362Efficient Algorithms Unlock Understanding of Clonal Evolution in Cancer.Blood Cancer Discov2022
35429619Recurrent transcriptional responses in AML and MDS patients treated with decitabine.Exp Hematol2022
35568002Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers.Cancer Genet2022
35864110Author Correction: A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing.Nat Commun2022
35041928Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence.J Mol Diagn2022
35313694Somatic <i>Dnmt3a</i> inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells.iScience2022
34873300Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells.Leukemia2022
35236053Decitabine salvage for <i>TP53</i>-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.Haematologica2022
35019859Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia.Blood Cancer Discov2022
33388420Enhanced Efficacy and Increased Long-Term Toxicity of CNS-Directed, AAV-Based Combination Therapy for Krabbe Disease.Mol Ther2021
33879241Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.Genome Med2021
33846253Dnmt3a deficiency in the skin causes focal, canonical DNA hypomethylation and a cellular proliferation phenotype.Proc Natl Acad Sci U S A2021
33704937Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers.N Engl J Med2021
34546980U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice.J Clin Invest2021
34780480Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype.PLoS One2021
34845035Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.Proc Natl Acad Sci U S A2021
34125173Tumor suppressor function of Gata2 in acute promyelocytic leukemia.Blood2021
34341766Bam-readcount - rapid generation of basepair-resolution sequence metrics.ArXiv2021
34315901Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.Nat Commun2021
34255749HPV transcript expression affects cervical cancer response to chemoradiation.JCI Insight2021
32369930Unmasking Intra-tumoral Heterogeneity and Clonal Evolution in NF1-MPNST.Genes (Basel)2020
31907209pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.Cancer Immunol Res2020
31996479Remethylation of <i>Dnmt3a</i><sup>-/-</sup> hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing.Proc Natl Acad Sci U S A2020
32577507The clonal evolution of metastatic colorectal cancer.Sci Adv2020
32868873HPV-EM: an accurate HPV detection and genotyping EM algorithm.Sci Rep2020
32133512Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine.Neuro Oncol2020
32484854Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post-allogeneic hematopoietic stem cell transplant patient.Blood Adv2020
30467844Exome analysis of treatment-related AML after APL suggests secondary evolution.Br J Haematol2019
31413257A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing.Nat Commun2019
30923101Shared cell of origin in a patient with Erdheim-Chester disease and acute myeloid leukemia.Haematologica2019
30906654Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma.Oncoimmunology2019
30553776Smc3 is required for mouse embryonic and adult hematopoiesis.Exp Hematol2019
29092827Somatic mutations and clonal hematopoiesis in congenital neutropenia.Blood2018
29891591A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel <i>RARG</i>-<i>CPSF6</i> fusion.Blood Adv2018
30181556The prognostic effects of somatic mutations in ER-positive breast cancer.Nat Commun2018
30207916Mutation Clearance after Transplantation for Myelodysplastic Syndrome.N Engl J Med2018
29959414Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS.Leukemia2018
29872146Somatic mutations in benign breast disease tissue and risk of subsequent invasive breast cancer.Br J Cancer2018
30429476Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer.Nat Commun2018
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Collaborators

Timothy J Ley
Washington University School of Medicine
Co-authored papers 60
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 58
Richard K Wilson
The Ohio State University
Co-authored papers 44
Elaine R Mardis
The Ohio State University
Co-authored papers 42
Matthew J Walter
Washington University School of Medicine in St. Louis
Co-authored papers 35
John F DiPersio
Washington University School of Medicine
Co-authored papers 33
Daniel C Link
Washington University School of Medicine
Co-authored papers 31
Catrina Fronick
McDonnell Genome Institute, Washington University in St. Louis School of Medicine
Co-authored papers 30
Peter Westervelt
Washington University School of Medicine
Co-authored papers 30
Sharon E Heath
Washington University School of Medicine.
Co-authored papers 28
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
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Malachi Griffith
Washington University
Co-authored papers 24
Obi L Griffith
Washington University
Co-authored papers 23
Michelle O'Laughlin
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 22
Timothy A Graubert
Massachusetts General Hospital
Co-authored papers 21
David E Larson
McDonnell Genome Institute, Washington University School of Medicine
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Michael D McLellan
McDonnell Genome Institute, Washington University in St. Louis
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Lukas D Wartman
Washington University School of Medicine in St. Louis
Co-authored papers 18
Joshua F McMichael
Washington University
Co-authored papers 18
Vincent Magrini
The Ohio State University
Co-authored papers 16
David H Spencer
Washington University School of Medicine.
Co-authored papers 15
Charles Lu
Co-authored papers 15
Jeffery M Klco
St. Jude Children's Research Hospital
Co-authored papers 14
Jasreet Hundal
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 14
Jason Walker
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 13
Jacqueline E Payton
Washington University School of Medicine.
Co-authored papers 13
Michael C Wendl
Washington University in St Louis
Co-authored papers 12
Zachary L Skidmore
Washington University in St. Louis School of Medicine
Co-authored papers 10
Christopher A Maher
Washington University in St Louis
Co-authored papers 10
Cyriac Kandoth
University of California los angeles
Co-authored papers 9
Release 1.2