Author details

Full Name

Melanie D Ohi

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36534787	Structural Insights into the Advances and Mechanistic Understanding of Human Dicer.		2023
37613758	Characterization of Two New Proteins Found in the L. pneumophila Dot/Icm T4SS.		2023
37264140	Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand.		2023
37130292	Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA.		2023
36870682	Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in the assembly of oligomeric complexes.	J Biol Chem	2023
36993335	A mechanistic model of primer synthesis from catalytic structures of DNA polymerase Î±-primase.	bioRxiv	2023
35544577	Molecular architecture of the human caveolin-1 complex.	Sci Adv	2022
35972526	Emerging Insights into the Molecular Architecture of Caveolin-1.	Journal of Membrane Biology	2022
35951533	Molecular architecture of bacterial type IV secretion systems.	PLoS Pathogens	2022
34543122	Functional Properties of Oligomeric and Monomeric Forms of Helicobacter pylori VacA Toxin.	Infection and Immunity	2021
33893233	Ion mobility-mass spectrometry reveals the role of peripheral myelin protein dimers in peripheral neuropathy.	Proceedings of the National Academy of Sciences of the United States of America	2021
33676924	N-terminal Transmembrane-Helix Epitope Tag for X-ray Crystallography and Electron Microscopy of Small Membrane Proteins.	Journal of Molecular Biology	2021
34519271	Cryo-EM reveals new species-specific proteins and symmetry elements in the <i>Legionella pneumophila</i> Dot/Icm T4SS.	Elife	2021
33268374	Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy.	Science advances	2020
31942029	Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles.	Commun Biol	2020
31711756	Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.	Structure	2020
32451226	The Helicobacter pylori Cag Type IV Secretion System.	Trends in Microbiology	2020
33357436	Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis.	Cell Reports	2020
33301709	Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.	Cell	2020
31056463	Allosteric Regulation of Oligomerization by a B<sub>12</sub> Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria.	Cell Chem Biol	2019
30692181	Intracellular Degradation of Helicobacter pylori VacA Toxin as a Determinant of Gastric Epithelial Cell Viability.	Infect Immun	2019
30954575	Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization.	Journal of Molecular Biology	2019
31210639	Structure of the Cag type IV secretion system.	eLife	2019
29470533	Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins.	PLoS Pathog	2018
30029854	Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.	Immunity	2018
29985404	Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters.	Nature Communications	2018
29531133	Determinants of Raft Partitioning of the Helicobacter pylori Pore-Forming Toxin VacA.	Infection and Immunity	2018
27673321	While the revolution will not be crystallized, biochemistry reigns supreme.	Protein Sci	2017
28695207	Peripheral myelin protein 22 alters membrane architecture.	Sci Adv	2017
28705932	Use of a neutralizing antibody helps identify structural features critical for binding of toxin TcdA to the host cell surface.	Journal of Biological Chemistry	2017
28780959	Structural and functional analyses of the spliceosome requires a multi-disciplinary approach.	Methods	2017
29127291	Structural basis of arrestin-3 activation and signaling.	Nat Commun	2017
28232034	Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.	Journal of Molecular Biology	2017
27791117	Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.	Proc Natl Acad Sci U S A	2016
26758182	Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex.	mBio	2016
27382020	A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain.	Infection and Immunity	2016
27271669	An Overview of Helicobacter pylori VacA Toxin Biology.	Toxins	2016
26776521	The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis.	Cell Reports	2016
27309820	Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin.	Molecular Microbiology	2016
26702831	Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis.	Developmental Cell	2015
25600116	Glycolytic enzymes localize to ribonucleoprotein granules in Drosophila germ cells, bind Tudor and protect from transposable elements.	EMBO Rep	2015
25955078	Cryo-electron microscopy and the amazing race to atomic resolution.	Biochemistry	2015
26150501	Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8.	Proceedings of the National Academy of Sciences of the United States of America	2015
25263959	Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5.	Biochemistry	2014
25264249	Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanism.	Current Biology	2014
23509303	Molecular assembly of botulinum neurotoxin progenitor complexes.	Proceedings of the National Academy of Sciences of the United States of America	2013
24243016	Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease.	Cell	2013
24014766	Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.	Eukaryot Cell	2013
23388462	Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator.	Cell Cycle	2013
23178866	Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin.	J Mol Biol	2013