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Author Details

Kunio Matsumoto
Cancer Research Institute, Kanazawa University
1990
388
90
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35196631Dual blockade of MET and VEGFR2 signaling pathways as a potential therapeutic maneuver for peritoneal carcinomatosis in scirrhous gastric cancer.Biochem Biophys Res Commun2022
35092134N-glycosylation regulates MET processing and signaling.Cancer Sci2022
35085554SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells.J Biol Chem2022
34805784De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist.iScience2021
33574034CDCP1 promotes compensatory renal growth by integrating Src and Met signaling.Life Sci Alliance2021
35011963Placental Leucine Aminopeptidase as a Potential Specific Urine Biomarker for Invasive Ovarian Cancer.J Clin Med2021
34948276Recent Insights into Human Endometrial Peptidases in Blastocyst Implantation via Shedding of Microvesicles.Int J Mol Sci2021
34502141Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor Activation.Int J Mol Sci2021
32929081Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer.Nat Commun2020
31664167Retraction Note: Enhanced suppression of tumor growth using a combination of NK4 plasmid DNA-PEG engrafted cationized dextran complex and ultrasound irradiation.Cancer Gene Ther2020
31765716New insights into human endometrial aminopeptidases in both implantation and menstruation.Biochim Biophys Acta Proteins Proteom2020
31943091The constitutive high-affinity Met-binding site in the kringle domain is dispensable for the signalling activity of hepatocyte growth factor.J Biochem2020
33028834Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion.Sci Rep2020
33121208Cyclic Peptide-Based Biologics Regulating HGF-MET.Int J Mol Sci2020
31101918Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.Nat Chem Biol2019
31212972Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.Int J Mol Sci2019
31342590Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer.Cancer Sci2019
30322054MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner.Int J Mol Sci2018
30405161Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist.Sci Rep2018
28064454Hepatocyte growth factor/MET in cancer progression and biomarker discovery.Cancer Sci2017
28294470Exome sequencing deciphers a germline MET mutation in familial epidermal growth factor receptor-mutant lung cancer.Cancer Sci2017
28094206Hepatocyte growth factor in physiology and infectious diseases.Cytokine2017
28973887Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.Proc Natl Acad Sci U S A2017
28673936Targeting the hepatocyte growth factor/Met pathway in cancer.Biochem Soc Trans2017
26719536Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases.Cancer Res2016
27608665Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies.Sci Rep2016
27683122Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma.Oncotarget2016
25770121Hepatocyte growth factor and Met in drug discovery.J Biochem2015
26191485A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene.Springerplus2015
25758345Artificial human Met agonists based on macrocycle scaffolds.Nat Commun2015
24952482Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.Oncotarget2014
28548072HGF-Met Pathway in Regeneration and Drug Discovery.Biomedicines2014
25378205Pharmacokinetics and pharmacodynamics following intravenous administration of recombinant human hepatocyte growth factor in rats with renal injury.Pharmacology2014
24780821Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.Exp Cell Res2014
24828661Triple inhibition of EGFR, Met, and VEGF suppresses regrowth of HGF-triggered, erlotinib-resistant lung cancer harboring an EGFR mutation.J Thorac Oncol2014
23047829Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans.J Pharm Sci2013
24292413Novel long-acting prostacyclin agonist (ONO-1301) with an angiogenic effect: promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.J Pharmacol Sci2013
24386407Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.PLoS One2013
24118504Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.Cancer Sci2013
24190236Suppression of fibrogenic gene expression and liver fibrosis using a synthetic prostacyclin agonist.Biomed Res2013
23876175Molecular targeting of hepatocyte growth factor by an antagonist, NK4, in the treatment of rheumatoid arthritis.Arthritis Res Ther2013
24033722Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model.Cancer Sci2013
23690929mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF.PLoS One2013
23676973Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension.Circ J2013
23618918Met/HGF receptor activation is regulated by juxtamembrane Ser985 phosphorylation in hepatocytes.Cytokine2013
23722408Interruption of the HGF paracrine loop by NK4, an HGF antagonist, reduces VEGF expression of CT26 cells.Oncol Rep2013
23507559α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells.Cancer Lett2013
23233163HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells.Int J Oncol2013
23219794Beneficial effect of a synthetic prostacyclin agonist, ONO-1301, in rat autoimmune myocarditis model.Eur J Pharmacol2013
23319394The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor.Int J Cancer2013
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Collaborators

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Co-authored papers 1
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