Author details

Full Name

William A Catterall

Affiliation

ORCID

Career Start Year

1969

Papers

528

H Index

147

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36846334	Impairment of Î²-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac Ca1.2 calcium channel.		2023
37751687	Cell-cycle arrest at the G1/S boundary enhances transient voltage-gated ion channel expression in human and insect cells.		2023
37903281	Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.	J Gen Physiol	2023
37983307	Voltage gated sodium and calcium channels: Discovery, structure, function, and Pharmacology.		2023
36996107	Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na<sub>V</sub>1.7.	Proc Natl Acad Sci U S A	2023
35477860	Synaptotagmin-7 Enhances Facilitation of Ca2.1 Calcium Channels.	eNeuro	2022
36345826	Spatiotemporal Control of Vascular Ca1.2 by Î±1 S1928 Phosphorylation.	Circulation Research	2022
36215501	Convergent regulation of Ca1.2 channels by direct phosphorylation and by the small GTPase RAD in the cardiac fight-or-flight response.	Proceedings of the National Academy of Sciences of the United States of America	2022
34529831	THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels.	British Journal of Pharmacology	2021
34099183	Expression and purification of the cardiac sodium channel Na<sub>V</sub>1.5 for cryo-EM structure determination.	Methods Enzymol	2021
33769100	Sodium channelopathies of skeletal muscle and brain.	Physiological Reviews	2021
34308420	Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome.		2021
33232657	Structural Basis for High-Affinity Trapping of the Na<sub>V</sub>1.7 Channel in Its Resting State by Tarantula Toxin.	Mol Cell	2021
33397917	Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin.	Nat Commun	2021
33320951	Corrigendum to: Circadian regulation of sleep in a pre-clinical model of Dravet syndrome: dynamics of sleep stage and siesta re-entrainment.	Sleep	2021
34520724	Open-state structure and pore gating mechanism of the cardiac sodium channel.	Cell	2021
34733140	Sharp-Wave Ripple Frequency and Interictal Epileptic Discharges Increase in Tandem During Thermal Induction of Seizures in a Mouse Model of Genetic Epilepsy.	Frontiers in Cellular Neuroscience	2021
34618572	Edmond Fischer (1920-2021).	Science	2021
34728568	Autism-associated mutations in K7 channels induce gating pore current.	Proceedings of the National Academy of Sciences of the United States of America	2021
31537174	Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels.	Annual Review of Pharmacology and Toxicology	2020
31866066	Structure of the Cardiac Sodium Channel.	Cell	2020
33199904	The conformational cycle of a prototypical voltage-gated sodium channel.	Nat Chem Biol	2020
32848250	Computational design of transmembrane pores.	Nature	2020
31391290	Structural Basis for Diltiazem Block of a Voltage-Gated Ca<sup>2+</sup> Channel.	Mol Pharmacol	2019
31826954	IgGs from patients with amyotrophic lateral sclerosis and diabetes target CaÎ±Î´1 subunits impairing islet cell function and survival.	Proceedings of the National Academy of Sciences of the United States of America	2019
30510035	Molecular dissection of multiphase inactivation of the bacterial sodium channel Na<sub>V</sub>Ab.	J Gen Physiol	2019
30811980	The Role of Ca2.1 Channel Facilitation in Synaptic Facilitation.	Cell Reports	2019
31484365	Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels.	Toxins	2019
31265868	A more efficient conditional mouse model of Dravet syndrome: Implications for epigenetic selection and sex-dependent behaviors.	Journal of Neuroscience Methods	2019
31353218	Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.	Cell	2019
31346614	Circadian regulation of sleep in a pre-clinical model of Dravet syndrome: dynamics of sleep stage and siesta re-entrainment.	Sleep	2019
31346088	Hippocampal deletion of Na1.1 channels in mice causes thermal seizures and cognitive deficit characteristic of Dravet Syndrome.	Proceedings of the National Academy of Sciences of the United States of America	2019
31537705	Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome.	J Neurosci	2019
27956748	Association of rare missense variants in the second intracellular loop of Na<sub>V</sub>1.7 sodium channels with familial autism.	Mol Psychiatry	2018
29043505	Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.	Handbook of Experimental Pharmacology	2018
30123852	Dravet Syndrome: A Sodium Channel Interneuronopathy.	Current Opinion in Physiology	2018
30518562	Fenestrations control resting-state block of a voltage-gated sodium channel.	Proc Natl Acad Sci U S A	2018
29723500	Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease.	Neuron	2018
29654190	Control of Excitation/Inhibition Balance in a Hippocampal Circuit by Calcium Sensor Protein Regulation of Presynaptic Calcium Channels.	Journal of Neuroscience	2018
29743299	The AKAP Cypher/Zasp contributes to Î²-adrenergic/PKA stimulation of cardiac Ca1.2 calcium channels.	Journal of General Physiology	2018
29691040	Progress in Understanding and Treating SCN2A-Mediated Disorders.	Trends Neurosci	2018
29769724	Structural basis for gating pore current in periodic paralysis.	Nature	2018
28119465	Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the Î²2-adrenergic receptor in neurons.	Science Signaling	2017
28348242	Structures of closed and open states of a voltage-gated sodium channel.	Proc Natl Acad Sci U S A	2017
28589518	Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy.	Neurochemical Research	2017
28973916	Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome.	Proceedings of the National Academy of Sciences of the United States of America	2017
28406893	The chemical basis for electrical signaling.	Nat Chem Biol	2017
27864509	Loss of Î²-adrenergic-stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failure.	Proceedings of the National Academy of Sciences of the United States of America	2016
27247394	K(ATP) channel gain-of-function leads to increased myocardial L-type Ca(2+) current and contractility in Cantu syndrome.	Proceedings of the National Academy of Sciences of the United States of America	2016
26755594	Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to short-term synaptic plasticity in hippocampal neurons.	Proceedings of the National Academy of Sciences of the United States of America	2016