Author details

Full Name

Robert J Klein

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37544983	Examination of fully automated mammographic density measures using LIBRA and breast cancer risk in a cohort of 21,000 non-Hispanic white women.	Breast Cancer Res	2023
37205487	Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer.	medRxiv	2023
36707626	Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics.	NPJ Precis Oncol	2023
37264206	Genetically adjusted PSA levels for prostate cancer screening.	Nat Med	2023
36877497	Bringing Prostate Cancer Polygenic Risk Scores to the Clinic.		2023
36690614	MiXcan: a framework for cell-type-aware transcriptome-wide association studies with an application to breast cancer.	Nat Commun	2023
36608299	Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response.		2023
35297162	Polygenic risk scores and prostate cancer screening: a recipe for more overdiagnosis?	BJU International	2022
35396534	Prostate cancer polygenic risk score and prediction of lethal prostate cancer.	npj Precision Oncology	2022
35511739	SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death.	Cancer Epidemiology Biomarkers and Prevention	2022
35693291	Are polygenic risk scores ready for the cancer clinic?-a perspective.	Translational Lung Cancer Research	2022
35477182	Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer.	Cancer Epidemiol Biomarkers Prev	2022
35474001	Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2022
33419763	Functional Common and Rare <i>ERBB2</i> Germline Variants Cooperate in Familial and Sporadic Cancer Susceptibility.	Cancer Prev Res (Phila)	2021
33751038	Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes.	Hum Mol Genet	2021
33122083	Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing.	Gene	2021
33219367	Genome-wide association study identifies a role for the progesterone receptor in benign prostatic hyperplasia risk.	Prostate Cancer and Prostatic Diseases	2021
32728046	An integrative ENCODE resource for cancer genomics.	Nat Commun	2020
32065238	Prostate cancer risk SNP rs10993994 is a trans-eQTL for SNHG11 mediated through MSMB.	Human Molecular Genetics	2020
33037222	Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk.	Nat Commun	2020
32532924	Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted Î±-particle therapy.	Proc Natl Acad Sci U S A	2020
32866655	Inherited Rare, Deleterious Variants in ATM Increase Lung Adenocarcinoma Risk.	J Thorac Oncol	2020
32914890	Genome-wide association study identifies novel single nucleotide polymorphisms having age-specific effect on prostate-specific antigen levels.	Prostate	2020
32728249	Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2020
30718883	Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.	Eur J Hum Genet	2019
30538125	Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function.	Clinical Chemistry	2019
30425093	Rare, Pathogenic Germline Variants in Genes Increase Risk for Squamous Lung Cancer.	Clinical Cancer Research	2019
30967618	Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.	Leukemia	2019
29559475	Germline Lysine-Specific Demethylase 1 (<i>LSD1/KDM1A</i>) Mutations Confer Susceptibility to Multiple Myeloma.	Cancer Res	2018
30289108	Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival.		2018
29389935	Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk.	PLoS Genet	2018
29705978	High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.	Hum Genet	2018
28139693	Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.	Nat Commun	2017
28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
28832619	Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
29214033	Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.	Lupus Sci Med	2017
28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Am J Hum Genet	2017
24982446	Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.	J Clin Oncol	2016
27291797	Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.	Nat Commun	2016
27008888	Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes.	Hum Mol Genet	2016
26833098	Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.	Nat Commun	2016
26732429	Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.	Hum Mol Genet	2016
26723226	Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes.	Urol Oncol	2016
26358132	Collaborative science in the next-generation sequencing era: a viewpoint on how to combine exome sequencing data across sites to identify novel disease susceptibility genes.	Brief Bioinform	2016
26395054	WGSA: an annotation pipeline for human genome sequencing studies.	J Med Genet	2016
26505625	Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma.	Cancer	2016
27745836	Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing.	Am J Hum Genet	2016
27499155	Genetic markers of pigmentation are novel risk loci for uveal melanoma.	Scientific Reports	2016
27492892	Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies.	EBioMedicine	2016
27713484	A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer.	Sci Rep	2016