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Author Details

Harmen J G van de Werken
Department of Immunology Erasmus University Medical Center
2006
78
31
PMIDPaper TitleJournal TitlePublished Year
38063488TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model.J Immunol2024
36932139Evaluation of pre-processing methods for tear fluid proteomics using proximity extension assays.Sci Rep2023
38083327Classification of Inflammation of Unknown Origin patients based on RNA-seq and SomaScan data.Annu Int Conf IEEE Eng Med Biol Soc2023
37735204Overcoming immune checkpoint blockade resistance in solid tumors with intermittent ITK inhibition.Sci Rep2023
37771591Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK.Front Immunol2023
37158243Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients.Hepatology2023
37400554The genomic and transcriptomic landscape of advanced renal cell cancer for individualized treatment strategies.Sci Rep2023
36621142Identifying somatic changes in drug transporters using whole genome and transcriptome sequencing data of advanced tumors.Biomed Pharmacother2023
34608482The EGFRvIII transcriptome in glioblastoma: A meta-omics analysis.Neuro Oncol2022
37848617Katdetectr: an R/bioconductor package utilizing unsupervised changepoint analysis for robust kataegis detection.Gigascience2022
35442716Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors.J Clin Oncol2022
35662281Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.Oncogene2022
35860283Trained Immunity in Primary Sjögren's Syndrome: Linking Type I Interferons to a Pro-Atherogenic Phenotype.Front Immunol2022
35717359Reply to Yuxuan Song, Caipeng Qin, and Tao Xu's Letter to the Editor re: J. Alberto Nakauma-González, Maud Rijnders, Job van Riet, et al. Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma. Eur Urol 2022;81:331-6.Eur Urol2022
36429059Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling.Cells2022
33596640The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.Haematologica2022
35159112Identification of Early-Onset Metastasis in SF3B1 Mutated Uveal Melanoma.Cancers (Basel)2022
35177626Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning.Nat Commun2022
35086719Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.Eur Urol2022
35022662Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren's syndrome.Rheumatology (Oxford)2022
34864882ProteoDisco: a flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies.Bioinformatics2022
33006377The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder.Int J Cancer2021
33811251Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.Sci Rep2021
34891161Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data.Gigascience2021
35047820Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.Neurooncol Adv2021
34724897FASTAFS: file system virtualisation of random access compressed FASTA files.BMC Bioinformatics2021
34749299Continued androgen signalling inhibition improves cabazitaxel efficacy in prostate cancer.EBioMedicine2021
34326338The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets.Nat Commun2021
34036938Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.Elife2021
33932725Generating human prostate cancer organoids from leukapheresis enriched circulating tumour cells.Eur J Cancer2021
32163234Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients.Stem Cells Transl Med2020
32057596Synchronous and metachronous urothelial carcinoma of the upper urinary tract and the bladder: Are they clonally related? A systematic review.Urol Oncol2020
33427690Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer.J Immunother Cancer2020
30672466PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells.Elife2019
35100672Unique Case of a Rare Mesenchymal Tumor Harboring a Somatic c.119delC <i>VHL</i> Mutation.JCO Precis Oncol2019
31748536The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact.Nat Commun2019
30257989Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling.Mol Cancer Res2019
31570896The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.Nat Genet2019
31425584Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients.Invest Ophthalmol Vis Sci2019
31043383Correction: Functional <i>Ex Vivo</i> Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.Clin Cancer Res2019
29305224SNPitty: An Intuitive Web Application for Interactive B-Allele Frequency and Copy Number Visualization of Next-Generation Sequencing Data.J Mol Diagn2018
29914715Fractionated Radiation of Primary Prostate Basal Cells Results in Downplay of Interferon Stem Cell and Cell Cycle Checkpoint Signatures.Eur Urol2018
30157426Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling.Cell Rep2018
29929481Gene length corrected trimmed mean of M-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons.BMC Bioinformatics2018
30139880Functional <i>Ex Vivo</i> Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.Clin Cancer Res2018
29419817Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C.Nat Protoc2018
27916271Correlation of Gene Mutation Status with Copy Number Profile in Uveal Melanoma.Ophthalmology2017
28319171A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable.PLoS One2017
28341771Small chromosomal regions position themselves autonomously according to their chromatin class.Genome Res2017
28683324DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells.Cell Rep2017
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Collaborators

Job van Riet
Erasmus MC Cancer Institute
Co-authored papers 22
John W M Martens
Erasmus Medical Center (MC) Cancer Institute
Co-authored papers 10
Martijn P Lolkema
Erasmus MC Cancer Institute
Co-authored papers 9
Edwin Cuppen
Hartwig Medical Foundation
Co-authored papers 8
Geert J L H van Leenders
Erasmus MC Cancer Institute, University Medical Center
Co-authored papers 6
Stefan Sleijfer
Erasmus MC Cancer Institute, University Medical Center Rotterdam
Co-authored papers 6
Guido Jenster
Erasmus University Medical Center
Co-authored papers 6
Youri Hoogstrate
Erasmus MC Cancer Institute
Co-authored papers 5
Pim J French
Erasmus MC Cancer Institute
Co-authored papers 4
Ronald de Wit
Erasmus MC Cancer Institute
Co-authored papers 4
Emile E Voest
The Netherlands Cancer Institute
Co-authored papers 3
Carolien H M van Deurzen
Erasmus MC Cancer Institute
Co-authored papers 3
Paul Hamberg
Franciscus Gasthuis & Vlietland Hospital Rotterdam and Schiedam
Co-authored papers 3
Neeltje Steeghs
Netherlands Cancer Institute-Antoni Van Leeuwenhoek
Co-authored papers 3
Jeroen A A Demmers
Erasmus Medical Center
Co-authored papers 3
Hans Clevers
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
Lisanne F van Dessel
Erasmus MC Cancer Institute
Co-authored papers 2
Kristian Helin
The Institute of Cancer Research
Co-authored papers 2
Michiel S van der Heijden
the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital
Co-authored papers 2
Niven Mehra
Radboud university medical center
Co-authored papers 2
Serena Nik-Zainal
Early Cancer Institute, University of Cambridge
Co-authored papers 2
Jochen D Muehlschlegel
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Zhen Ye
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 1
Paul J van Diest
University Medical Center Utrecht
Co-authored papers 1
Katja K H Aben
Co-authored papers 1
Reiner Siebert
Co-authored papers 1
Elias Campo
Institute for Biomedical Research August Pi I Sunyer
Co-authored papers 1
Albin Sandelin
University of Copenhagen
Co-authored papers 1
Marc van de Wetering
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
Johan M Kros
Erasmus MC Cancer Institute, University Medical Center Rotterdam
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