Author details

Full Name

Frank B Furnari

Affiliation

University of California San Diego

ORCID

Career Start Year

1992

Papers

129

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38052106	Epidermal growth factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium.	Redox Biol	2024
36416495	Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma.	Neuro Oncol	2023
38024245	A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating <b>Î³</b>-secretase complex.	Neurooncol Adv	2023
37706203	Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.	Neurooncol Adv	2023
37461511	Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-ÎºB/BRD2 Chromatin Complex.	bioRxiv	2023
37343523	Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas.	Cell Rep Med	2023
37169593	Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network.	Life Sci Alliance	2023
36460775	Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy.	Cell Death Differ	2023
36865329	Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars.	bioRxiv	2023
35325218	TERT promoter C228T mutation in neural progenitors confers growth advantage following telomere shortening in vivo.	Neuro Oncol	2022
35603900	The impact of phosphorylated PTEN at threonine 366 on cortical connectivity and behaviour.	Brain	2022
36125064	EGFR, the Lazarus target for precision oncology in glioblastoma.	Neuro Oncol	2022
35305088	PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with TOP2A inhibitors.	Neuro Oncol	2022
32830856	Epidermal growth factor receptor as a molecular determinant of glioblastoma response to dopamine receptor D2 inhibitors.	Neuro Oncol	2021
33568479	Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer.	Sci Adv	2021
33846242	PI3KÎ³ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.	Proc Natl Acad Sci U S A	2021
34178638	A Key Pathway to Cancer Resilience: The Role of Autophagy in Glioblastomas.	Front Oncol	2021
33428749	PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.	Neuro Oncol	2021
32536682	Genome Engineering Evolves Brain Tumor Modeling.	Neurol Med Chir (Tokyo)	2020
31992716	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells.	Nat Commun	2020
31956073	Integrin Î±vÎ²5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy.	Cell Rep	2020
33243756	EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration.	J Cell Sci	2020
32912900	SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability.	Genes Dev	2020
32312984	Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells.	Nat Commun	2020
32361246	Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas.	EBioMedicine	2020
30659021	Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk.	Cancer Res	2019
31821785	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31303424	Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling.	Cell Metab	2019
31444232	Intron 1-Mediated Regulation of <i>EGFR</i> Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins.	Mol Cancer Res	2019
31040904	When less is more: Gaining power through gene rearrangement of amplified <i>EGFR</i>.	Oncotarget	2019
30827889	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31085179	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31028138	Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.	Proc Natl Acad Sci U S A	2019
31019297	NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling.	Nature	2019
29321665	FHL2 interacts with EGFR to promote glioblastoma growth.	Oncogene	2018
29887596	YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity.	Oncogene	2018
29990498	Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.	Cancer Cell	2018
30118375	Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin.	Autophagy	2018
29757276	Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts.	J Vis Exp	2018
29660021	Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development.	Neuro Oncol	2018
29799523	Publisher Correction: PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.	Nat Commun	2018
29760085	MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells.	Proc Natl Acad Sci U S A	2018
28011764	Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.	Proc Natl Acad Sci U S A	2017
28497778	PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.	Nat Commun	2017
28178237	Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.	Nature	2017
28724615	Glioblastoma cellular cross-talk converges on NF-ÎºB to attenuate EGFR inhibitor sensitivity.	Genes Dev	2017
26755074	Epidermal growth factor receptor targeting and challenges in glioblastoma.	Neuro Oncol	2016
27746144	An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.	Cancer Cell	2016
27825958	Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.	J Control Release	2016
26980765	The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).	Cancer Res	2016

1 - 50 of 129

Briana C Prager

Massachusetts General Hospital

Career Start Year 2015

Number of shared co-authors 11

Jason K Sa

Korea University, College of Medicine

Career Start Year 2015

Number of shared co-authors 9

Veronique Frattini

Institute for Cancer Genetics, Columbia University Medical Center

Career Start Year 2011

Number of shared co-authors 2

Wei Zhang

University of Manchester

Career Start Year 2011

Number of shared co-authors 6

Maxim Sidorov

California Pacific Medical Center Research Institute

Career Start Year 2009

Number of shared co-authors 4

Joanna J Phillips

University of California san francisco

Career Start Year 2006

Number of shared co-authors 22

Chitra Venugopal

McMaster Stem Cell and Cancer Research Institute

Career Start Year 2006

Number of shared co-authors 4

Roel G W Verhaak

Yale School of Medicine

Career Start Year 2004

Number of shared co-authors 30

Anita B Hjelmeland

University of Alabama at Birmingham

Career Start Year 2004

Number of shared co-authors 4

Mario L Suv??

Broad Institute of MIT and Harvard

Career Start Year 2004

Number of shared co-authors 12

Massimo Squatrito

Seve Ballesteros Foundation Brain Tumor group

Career Start Year 2002

Number of shared co-authors 3

Jeongwu Lee

Lerner Research Institute, Cleveland Clinic

Career Start Year 2001

Number of shared co-authors 3

Agnieszka Bronisz

Mossakowski Medical Research Institute, Polish Academy of Sciences

Career Start Year 1999

Number of shared co-authors 3

Krishna P Bhat

Department of Neurosurgery at the University of Texas MD Anderson Cancer Center

Career Start Year 1998

Number of shared co-authors 11

Shwetal Mehta

Barrow Neurological Institute, St. Joseph's Hospital and Medical Center

Career Start Year 1998

Number of shared co-authors 2

Dimpy Koul

The University of Texas MD Anderson Cancer Center

Career Start Year 1996

Number of shared co-authors 7

Pim J French

Erasmus MC Cancer Institute

Career Start Year 1995

Number of shared co-authors 17

Gurpreet S Kapoor

Collegeville

Career Start Year 1995

Number of shared co-authors 2

Timothy A Chan

Cleveland Clinic.

Career Start Year 1994

Number of shared co-authors 18

Richard J Gilbertson

Cancer Research UK Cambridge Institute, University of Cambridge

Career Start Year 1992

Number of shared co-authors 17

John Easton

St Jude Children's Research Hospital

Career Start Year 1991

Number of shared co-authors 6

Candelaria Gomez-Manzano

The University of Texas M.D. Anderson Cancer Center

Career Start Year 1990

Number of shared co-authors 13

Howard Colman

Huntsman Cancer Institute, University of Utah

Career Start Year 1990

Number of shared co-authors 24

Howard A Fine

Meyer Cancer Center

Career Start Year 1990

Number of shared co-authors 9

Antonio Iavarone

Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami

Career Start Year 1989

Number of shared co-authors 18

E Alejandro Sweet-Cordero

University of California San Francisco

Career Start Year 1989

Number of shared co-authors 3

Wei Zhang

The University of Texas MD Anderson Cancer Center

Career Start Year 1988

Number of shared co-authors 16

Erwin G Van Meir

Heersink School of Medicine, University of Alabama at Birmingham

Career Start Year 1984

Number of shared co-authors 28

Joshua B Rubin

Washington University in St. Louis

Career Start Year 1983

Number of shared co-authors 11

Wai-Kwan Alfred Yung

University of Texas M.D. Anderson Cancer Center

Career Start Year 1974

Number of shared co-authors 25

row(s) 1 - 30 of 30

Webster K Cavenee

Ludwig Institute for Cancer Research, University of California San Diego

Co-authored papers 86

Paul S Mischel

Stanford University

Co-authored papers 18

Clark C Chen

University of Minnesota

Co-authored papers 16

H-J Su Huang

Regeneron Pharmaceuticals Inc.

Co-authored papers 11

Timothy F Cloughesy

David Geffen School of Medicine, University of California Los Angeles

Co-authored papers 10

Scott R VandenBerg

University of California san francisco

Co-authored papers 8

Oliver B??gler

American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University

Co-authored papers 7

Andrew K Shiau

Co-authored papers 6

Lynda Chin

Co-authored papers 6

Ryo Nishikawa

Saitama Medical University International Medical Center

Co-authored papers 6

Terrance G Johns

Telethon Kids Institute

Co-authored papers 6

Cameron Brennan