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Author Details

Lie Li
Sino-French Hoffmann Institute, Guangzhou Medical University
2003
40
25
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36572190A new intracellular targeting motif in the cytoplasmic tail of the spike protein may act as a target to inhibit SARS-CoV-2 assembly.Antiviral Res2023
37076694Preclinical pharmacokinetic and pharmacodynamic evaluation of dasatinib and ponatinib for the treatment of T-cell acute lymphoblastic leukemia.Leukemia2023
34866312Dasatinib does not exacerbate dexamethasone-induced osteonecrosis in murine models of acute lymphoblastic leukemia therapy.Pediatr Blood Cancer2022
35344039Preclinical and Pilot Study of Type I FLT3 Tyrosine Kinase Inhibitor, Crenolanib, with Sorafenib in Acute Myeloid Leukemia and FLT3-Internal Tandem Duplication.Clin Cancer Res2022
35370795Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus.Front Physiol2022
36278187Safety and efficacy of remimazolam besylate in patients undergoing colonoscopy: A multicentre, single-blind, randomized, controlled, phase â¿¢ trial.Front Pharmacol2022
32675219Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice.Haematologica2021
33742760Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.Clin Transl Sci2021
32094176Massively parallel variant characterization identifies <i>NUDT15</i> alleles associated with thiopurine toxicity.Proc Natl Acad Sci U S A2020
30714450L-carnitine does not ameliorate asparaginase-associated hepatotoxicity in a C57BL6 mouse model.Leuk Lymphoma2019
31455680Sorafenib Population Pharmacokinetics and Skin Toxicities in Children and Adolescents with Refractory/Relapsed Leukemia or Solid Tumor Malignancies.Clin Cancer Res2019
29227282Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia.J Clin Invest2018
29572377Preclinical evaluation of <i>NUDT15</i>-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.Blood2018
28689374Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.Clin Transl Sci2017
28409853A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study (POE 10-03).Pediatr Blood Cancer2017
28371445Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide.Clin Transl Sci2017
28209616OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.Cancer Res2017
26842729ABCC4 Is a Determinant of Cytarabine-Induced Cytotoxicity and Myelosuppression.Clin Transl Sci2016
26663398Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia.Clin Pharmacol Ther2016
27125973Evaluation of artemisinins for the treatment of acute myeloid leukemia.Cancer Chemother Pharmacol2016
26878724NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.Nat Genet2016
26979622A phosphotyrosine switch regulates organic cation transporters.Nat Commun2016
25952649Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.Cancer Res2015
26321221Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.Cancer Cell2015
25848011Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions.Proc Natl Acad Sci U S A2015
24916697Cisplatin-induced renal injury is independently mediated by OCT2 and p53.Clin Cancer Res2014
23340295Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.Clin Cancer Res2013
23863876Conjunctive therapy of cisplatin with the OCT2 inhibitor cimetidine: influence on antitumor efficacy and systemic clearance.Clin Pharmacol Ther2013
23794731Contribution of ABCC4-mediated gastric transport to the absorption and efficacy of dasatinib.Clin Cancer Res2013
23788485Alternative formulations of sorafenib for use in children.Pediatr Blood Cancer2013
22117778Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice.J Neurochem2012
22927483Ontogeny and sorafenib metabolism.Clin Cancer Res2012
22835831A structural and functional analysis of Nna1 in Purkinje cell degeneration (pcd) mice.FASEB J2012
21768474Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.J Clin Oncol2011
20870468Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry.J Chromatogr B Analyt Technol Biomed Life Sci2010
19344768Characterization of trans-neuronal trafficking of Cbln1.Mol Cell Neurosci2009
16952463The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype.Mol Cell Neurosci2006
17030622Cbln1 is essential for interaction-dependent secretion of Cbln3.Mol Cell Biol2006
16234806Cbln1 is essential for synaptic integrity and plasticity in the cerebellum.Nat Neurosci2005
12782575Mouse embryos cloned from brain tumors.Cancer Res2003
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Collaborators

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Ohio State University
Co-authored papers 19
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The Ohio State University
Co-authored papers 13
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Ohio State University
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The Ohio State University
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The Ohio State University
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Co-authored papers 6
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Departments of Pharmaceutical Sciences.
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School of Pharmacy and Pharmaceutical Sciences, University at Buffalo
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Second Affiliated Hospital of Harbin Medical University
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University Hospital Munster
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Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 3
Su Sien Ong
St. Jude Children's Research Hospital
Co-authored papers 2
Wenwei Lin
St. Jude Children's Research Hospital
Co-authored papers 2
Anne T Nies
and University of Tuebingen, University of Tuebingen
Co-authored papers 2
Kristine R Crews
St. Jude Children's Research Hospital
Co-authored papers 2
Jan H M Schellens
Department of Pharmaceutical Sciences, Utrecht University
Co-authored papers 2
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Rachel A Ness
4Department of Pharmacy, Memphis Veterans Affairs Medical Center
Co-authored papers 1
Sasan Zandi
University of Toronto
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Smita Bhatia
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Release 1.2