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Author Details

Robertus A M de Bruin
University College London, UK UCL Cancer Institute
1998
40
20
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37977116Genome homeostasis defects drive enlarged cells into senescence.Mol Cell2023
37977119Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition.Mol Cell2023
34508254Cell cycle control in cancer.Nat Rev Mol Cell Biol2022
35689667A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells.Metallomics2022
35216024Vaccinia Virus Arrests and Shifts the Cell Cycle.Viruses2022
33713703Tos4 mediates gene expression homeostasis through interaction with HDAC complexes independently of H3K56 acetylation.J Biol Chem2021
33855165Control of S phase duration: a replication capacity model with E2F transcription at its heart.Mol Cell Oncol2021
32349972<i>EZH2</i>-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.Cancer Discov2020
32665547E2F-dependent transcription determines replication capacity and S phase length.Nat Commun2020
32764038The proteasome controls ESCRT-III-mediated cell division in an archaeon.Science2020
28744706The evolution of a G1/S transcriptional network in yeasts.Curr Genet2018
28903048Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription.Cell Rep2017
28257104The Role of the Transcriptional Response to DNA Replication Stress.Genes (Basel)2017
28122869A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages.EMBO J2017
28754774Correction for Travesa et al., "Repression of G<sub>1</sub>/S Transcription Is Mediated via Interaction of the GTB Motifs of Nrm1 and Whi5 with Swi6".Mol Cell Biol2017
28505153Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness.PLoS Genet2017
27160911Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage.Cell Rep2016
27684184Bringing Functional Genomics into Focus.Cell Syst2016
24906330Analyzing G1-S transcriptional control.Methods Mol Biol2014
25533348Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability.Cell Rep2014
24986860Turning cell cycle entry on its head.Elife2014
23382076Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6.Mol Cell Biol2013
23877564Control of cell cycle transcription during G1 and S phases.Nat Rev Mol Cell Biol2013
23954429Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription.Curr Biol2013
23593391Binding specificity of the G1/S transcriptional regulators in budding yeast.PLoS One2013
22333912Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes.EMBO J2012
22895177The checkpoint transcriptional response: make sure to turn it off once you are satisfied.Cell Cycle2012
22333915DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1.EMBO J2012
21359180Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active.PLoS One2011
19158488All eukaryotes: before turning off G1-S transcription, please check your DNA.Cell Cycle2009
19714215The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback.PLoS Genet2009
19172996Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae.PLoS One2009
18160399The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae.J Biol Chem2008
18794370Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit.Mol Cell Biol2008
18682565DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1.Proc Natl Acad Sci U S A2008
17936710Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.Mol Cell2007
16916637Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback.Mol Cell2006
15210110Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5.Cell2004
11710836Identification of gene clusters differentially expressed during the cellular injury responses (CIR) to cisplatin.Br J Cancer2001
9619444Prediction-based threading of the hMSH2 DNA mismatch repair protein.FASEB J1998
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Release 1.2