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Author Details

Martijn P Lolkema
Erasmus MC Cancer Institute
1999
150
43
PMIDPaper TitleJournal TitlePublished Year
35976415A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer.Cancer Immunol Immunother2023
38061007Liquid Biopsies for Early Response Evaluation of Radium-223 in Metastatic Prostate Cancer.JCO Precis Oncol2023
37686693Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling.Cancers (Basel)2023
37119523Phase II study (KAMELEON) of single-agent T-DM1 in patients with HER2-positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma.Cancer Med2023
36983083A Compendium of AR Splice Variants in Metastatic Castration-Resistant Prostate Cancer.Int J Mol Sci2023
37178439mFast-SeqS-based aneuploidy score in circulating cell-free DNA is a prognostic biomarker in prostate cancer.Mol Oncol2023
37400554The genomic and transcriptomic landscape of advanced renal cell cancer for individualized treatment strategies.Sci Rep2023
37031196Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning.Nat Commun2023
37260332A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer.Oncologist2023
36209982Streamlining clinical research: an ESMO awareness call to improve sponsoring and monitoring of clinical trials.Ann Oncol2023
34615718Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors.Clin Cancer Res2022
35775194Correction: A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation.Clin Cancer Res2022
35710239Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phase I, open-label, single-arm, dose-escalation study (REACtiVe-2 trial).BMJ Open2022
35606463Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing.Br J Cancer2022
35669415Liquid Biopsy Based Circulating Biomarkers in Metastatic Prostate Cancer.Front Oncol2022
35717359Reply to Yuxuan Song, Caipeng Qin, and Tao Xu's Letter to the Editor re: J. Alberto Nakauma-González, Maud Rijnders, Job van Riet, et al. Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma. Eur Urol 2022;81:331-6.Eur Urol2022
36481665Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.Nat Commun2022
36147916Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study.Front Oncol2022
36139564Characterizing Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles in Metastatic Castration-Naive and Castration-Resistant Prostate Cancer Patients.Cancers (Basel)2022
35895277Influence of Darolutamide on Cabazitaxel Systemic Exposure.Clin Pharmacokinet2022
36323051CABA-V7: a prospective biomarker selected trial of cabazitaxel treatment in AR-V7 positive prostate cancer patients.Eur J Cancer2022
35046062Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.Clin Cancer Res2022
35181986Genome-wide aneuploidy detected by mFast-SeqS in circulating cell-free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer.Mol Oncol2022
35086719Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.Eur Urol2022
35326653Decisional Conflict after Deciding on Potential Participation in Early Phase Clinical Cancer Trials: Dependent on Global Health Status, Satisfaction with Communication, and Timing.Cancers (Basel)2022
34615720Anti-PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8<sup>+</sup> T cells.Clin Cancer Res2022
33119892Effects of Protein and Calorie Restriction on the Metabolism and Toxicity Profile of Irinotecan in Cancer Patients.Clin Pharmacol Ther2021
33571468SARS-CoV-2 vaccination and phase 1 cancer clinical trials.Lancet Oncol2021
33761899Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer.BMC Cancer2021
33556368Validation of circulating steroid hormone measurements across different matrices by liquid chromatography-tandem mass spectrometry.Steroids2021
33495476Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.Nat Commun2021
34409743Evaluation of the Khorana, PROTECHT, and 5-SNP scores for prediction of venous thromboembolism in patients with cancer.J Thromb Haemost2021
34670587High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments.Clin Epigenetics2021
34518310A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation.Clin Cancer Res2021
34749299Continued androgen signalling inhibition improves cabazitaxel efficacy in prostate cancer.EBioMedicine2021
34422118Circulating <i>TP53</i> mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX.Ther Adv Med Oncol2021
34132450A Phase I, First-in-Human Study of GSK2849330, an Anti-HER3 Monoclonal Antibody, in HER3-Expressing Solid Tumors.Oncologist2021
34045764Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer.Nat Genet2021
34326338The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets.Nat Commun2021
33965892Identifying patient values impacting the decision whether to participate in early phase clinical cancer trials: A systematic review.Cancer Treat Rev2021
34039979Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.Nat Commun2021
33932725Generating human prostate cancer organoids from leukapheresis enriched circulating tumour cells.Eur J Cancer2021
34006333Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients.Genome Med2021
34359641Docetaxel Skin Exposure and Micronucleation Contributes to Skin Toxicity Caused by CPC634.Cancers (Basel)2021
34337548Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine.Eur Urol Open Sci2021
34373653Limited evolution of the actionable metastatic cancer genome under therapeutic pressure.Nat Med2021
3397456011-Ketotestosterone is the predominant active androgen in prostate cancer patients after castration.JCI Insight2021
31395751Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations.Oncologist2020
31667659Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).Invest New Drugs2020
32024849A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.Nat Commun2020
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Collaborators

The Netherlands Cancer Institute
Co-authored papers 40
Erasmus MC Cancer Institute, University Medical Center Rotterdam
Co-authored papers 32
Erasmus MC Cancer Institute
Co-authored papers 29
Netherlands Cancer Institute-Antoni Van Leeuwenhoek
Co-authored papers 23
Erasmus Medical Center (MC) Cancer Institute
Co-authored papers 23
Hartwig Medical Foundation
Co-authored papers 21
Department of Pharmaceutical Sciences, Utrecht University
Co-authored papers 20
Franciscus Gasthuis & Vlietland Hospital Rotterdam and Schiedam
Co-authored papers 20
Erasmus MC Cancer Institute
Co-authored papers 14
University Medical Center Utrecht
Co-authored papers 9
Erasmus MC Cancer Institute
Co-authored papers 9
Department of Immunology Erasmus University Medical Center
Co-authored papers 9
Radboud university medical center
Co-authored papers 7
The Institute for Cancer Research
Co-authored papers 7
Radboud University Medical Center
Co-authored papers 4
Erasmus University Medical Center
Co-authored papers 4
Erasmus MC Cancer Institute, University Medical Center
Co-authored papers 3
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 3
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 3
University Medical Centre Mannheim, University of Heidelberg
Co-authored papers 3
the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital
Co-authored papers 3
Cancer Research UK Manchester Institute, University of Manchester
Co-authored papers 3
Princess Margaret Cancer Centre, University Ave
Co-authored papers 3
University Medical Center Utrecht
Co-authored papers 3
University of Zagreb
Co-authored papers 2
Sloan Kettering Institute
Co-authored papers 2
Brody School of Medicine, East Carolina University
Co-authored papers 2
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 2
Ohio State University
Co-authored papers 2
GZA Ziekenhuizen Campus Sint-Augustinus, University of Antwerp
Co-authored papers 2