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Author Details

Daniel Martinez
Perelman School of Medicine at the University of Pennsylvania
2002
57
30
PMIDPaper TitleJournal TitlePublished Year
37235472Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2023
37611092A MYCN-independent mechanism mediating secretome reprogramming and metastasis in <i>MYCN</i>-amplified neuroblastoma.Sci Adv2023
37235472Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2023
37611092A MYCN-independent mechanism mediating secretome reprogramming and metastasis in <i>MYCN</i>-amplified neuroblastoma.Sci Adv2023
36381237Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.Cancer Res Commun2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
35861867Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma.Clin Cancer Res2022
36396952Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.Commun Biol2022
36381237Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.Cancer Res Commun2022
36460335GPC2 antibody-drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies.J Immunother Cancer2022
35861867Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma.Clin Cancer Res2022
36396952Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.Commun Biol2022
36460335GPC2 antibody-drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies.J Immunother Cancer2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
34337560A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope.Cell Rep Med2021
33789113Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2021
33523558Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.Mol Oncol2021
33619171The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.Clin Cancer Res2021
33615184PARP Targeted Alpha-Particle Therapy Enhances Response to PD-1 Immune-Checkpoint Blockade in a Syngeneic Mouse Model of Glioblastoma.ACS Pharmacol Transl Sci2021
33603169HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.Oncogene2021
34337560A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope.Cell Rep Med2021
34732890Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.Nature2021
34644147Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.Sci Transl Med2021
33603169HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.Oncogene2021
33789113Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2021
33619171The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.Clin Cancer Res2021
33615184PARP Targeted Alpha-Particle Therapy Enhances Response to PD-1 Immune-Checkpoint Blockade in a Syngeneic Mouse Model of Glioblastoma.ACS Pharmacol Transl Sci2021
33523558Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.Mol Oncol2021
34644147Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.Sci Transl Med2021
34732890Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.Nature2021
32558936SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.J Pathol2020
31912158SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors.Neuro Oncol2020
31887631B7-H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors.Transl Oncol2020
32211329CAMKV Is a Candidate Immunotherapeutic Target in <i>MYCN</i> Amplified Neuroblastoma.Front Oncol2020
32206779Increased mTOR activation in idiopathic multicentric Castleman disease.Blood2020
32558936SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.J Pathol2020
31887631B7-H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors.Transl Oncol2020
31912158SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors.Neuro Oncol2020
32211329CAMKV Is a Candidate Immunotherapeutic Target in <i>MYCN</i> Amplified Neuroblastoma.Front Oncol2020
32206779Increased mTOR activation in idiopathic multicentric Castleman disease.Blood2020
30334904Prevalence and Clinical Correlations of Somatostatin Receptor-2 (SSTR2) Expression in Neuroblastoma.J Pediatr Hematol Oncol2019
30334904Prevalence and Clinical Correlations of Somatostatin Receptor-2 (SSTR2) Expression in Neuroblastoma.J Pediatr Hematol Oncol2019
30867324An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.Sci Transl Med2019
31072830Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.Mol Cancer Ther2019
30718512CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.Nat Commun2019
30718506SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.Nat Commun2019
31072830Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.Mol Cancer Ther2019
30867324An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.Sci Transl Med2019
30718512CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.Nat Commun2019
30718506SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.Nat Commun2019
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Collaborators

John M Maris
Children's Hospital of Philadelphia
Co-authored papers 21
Alexander R Judkins
Co-authored papers 12
Sriram Venneti
Co-authored papers 10
Mariarita Santi
Children's Hospital of Philadelphia
Co-authored papers 10
Komal S Rathi
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 9
Pichai Raman
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 7
Kristopher R Bosse
Co-authored papers 7
Yimei Li
Co-authored papers 5
John Q Trojanowski
University of Pennsylvania
Co-authored papers 5
Virginia M-Y Lee
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 5
Yael P Mosse
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 4
Khushbu Patel
Children's Hospital of Philadelphia
Co-authored papers 4
Dimiter S Dimitrov
Co-authored papers 4
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 4
Nathan M Kendsersky
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 4
Jennifer Pogoriler
Children's Hospital Of Philadelphia
Co-authored papers 4
Maria V Lane
Co-authored papers 4
Kateryna Krytska
University of Pennsylvania Perelman School of Medicine
Co-authored papers 3
Lori S Hart
Children's Hospital of Philadelphia, USA. [2] Center for Childhood Cancer Research
Co-authored papers 3
Alvin Farrel
Children's Hospital of Philadelphia
Co-authored papers 3
William D Foulkes
Segal Cancer Centre, Jewish General Hospital
Co-authored papers 3
Tom Curran
Medical University of South Carolina
Co-authored papers 3
Kristina A Cole
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Chung-Yip Chan
Co-authored papers 3
Tracy K McIntosh
University of Pennsylvania
Co-authored papers 2
Md Zahidul Alam
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Krutika S Gaonkar
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 2
Drew Pratt
Co-authored papers 2
Ian W Folkert
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Cynthia Hawkins
The Hospital for Sick Children
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