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Author Details

Zechen Chong
Heersink School of Medicine, University of Alabama at Birmingham
2011
38
21
Jake Y. Chen (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36650186Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak.Nat Commun2023
36650186Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak.Nat Commun2023
36152748Protein arginine methyltransferase 1 in the generation of immune megakaryocytes: A perspective review.J Biol Chem2022
36152748Protein arginine methyltransferase 1 in the generation of immune megakaryocytes: A perspective review.J Biol Chem2022
36008408Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling.Nat Commun2022
35994499Reduced sister chromatid cohesion acts as a tumor penetrance modifier.PLoS Genet2022
35546658B-assembler: a circular bacterial genome assembler.BMC Genomics2022
35546658B-assembler: a circular bacterial genome assembler.BMC Genomics2022
35994499Reduced sister chromatid cohesion acts as a tumor penetrance modifier.PLoS Genet2022
36008408Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling.Nat Commun2022
31180898Scalable De Novo Genome Assembly Using a Pregel-Like Graph-Parallel System.IEEE/ACM Trans Comput Biol Bioinform2021
33632895Haplotype-resolved diverse human genomes and integrated analysis of structural variation.Science2021
33554118ClipSV: improving structural variation detection by read extension, spliced alignment and tree-based decision rules.NAR Genom Bioinform2021
34775997Accurate long-read de novo assembly evaluation with Inspector.Genome Biol2021
35121884RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4<sup>+</sup> T-cell-dependent antitumor immunity.Nat Cancer2021
31180898Scalable De Novo Genome Assembly Using a Pregel-Like Graph-Parallel System.IEEE/ACM Trans Comput Biol Bioinform2021
33554118ClipSV: improving structural variation detection by read extension, spliced alignment and tree-based decision rules.NAR Genom Bioinform2021
33632895Haplotype-resolved diverse human genomes and integrated analysis of structural variation.Science2021
35121884RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4<sup>+</sup> T-cell-dependent antitumor immunity.Nat Cancer2021
34775997Accurate long-read de novo assembly evaluation with Inspector.Genome Biol2021
32568209Ozone and Particulate Matter Exposure and Alzheimer's Disease: A Review of Human and Animal Studies.J Alzheimers Dis2020
32568209Ozone and Particulate Matter Exposure and Alzheimer's Disease: A Review of Human and Animal Studies.J Alzheimers Dis2020
30827684Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2.Cell2019
30827684Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2.Cell2019
29696747Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.Hum Mutat2018
30030418Regenerative Potential of Neonatal Porcine Hearts.Circulation2018
30400818Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.Genome Biol2018
30013058In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.Nat Commun2018
30039369Structural Variant Breakpoint Detection with novoBreak.Methods Mol Biol2018
29696747Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.Hum Mutat2018
30013058In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.Nat Commun2018
30039369Structural Variant Breakpoint Detection with novoBreak.Methods Mol Biol2018
30030418Regenerative Potential of Neonatal Porcine Hearts.Circulation2018
30400818Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.Genome Biol2018
27892959novoBreak: local assembly for breakpoint detection in cancer genomes.Nat Methods2017
28439535A murine preclinical syngeneic transplantation model for breast cancer precision medicine.Sci Adv2017
27892959novoBreak: local assembly for breakpoint detection in cancer genomes.Nat Methods2017
28235197An Organismal CNV Mutator Phenotype Restricted to Early Human Development.Cell2017
28439535A murine preclinical syngeneic transplantation model for breast cancer precision medicine.Sci Adv2017
28235197An Organismal CNV Mutator Phenotype Restricted to Early Human Development.Cell2017
26806015Functional annotation of rare gene aberration drivers of pancreatic cancer.Nat Commun2016
26806015Functional annotation of rare gene aberration drivers of pancreatic cancer.Nat Commun2016
27356755Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.BMC Genomics2016
27841430Single-cell isolation by a modular single-cell pipette for RNA-sequencing.Lab Chip2016
27841430Single-cell isolation by a modular single-cell pipette for RNA-sequencing.Lab Chip2016
27356755Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.BMC Genomics2016
25762640Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia.Oncotarget2015
25918555ClinSeK: a targeted variant characterization framework for clinical sequencing.Genome Med2015
25626406Clinical actionability enhanced through deep targeted sequencing of solid tumors.Clin Chem2015
25762640Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia.Oncotarget2015
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Collaborators

Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 14
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 7
Wanding Zhou
University of Pennsylvania
Co-authored papers 7
Jue Ruan
Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences
Co-authored papers 5
Tenghui Chen
MD Anderson Cancer Center
Co-authored papers 5
Funda Meric-Bernstam
University of Texas MD Anderson Cancer Center
Co-authored papers 4
Xian Fan
Rice University
Co-authored papers 3
Chad J Creighton
Co-authored papers 3
James R Lupski
Baylor College of Medicine
Co-authored papers 3
Donna M Muzny
Baylor College of Medicine
Co-authored papers 3
Mark Gerstein
Yale University
Co-authored papers 2
Benjamin Raeder
Co-authored papers 2
Marjorie Withers
Baylor College of Medicine
Co-authored papers 2
Paul C Boutros
University of California los angeles
Co-authored papers 2
Jake Y. Chen (CM4AI)
University of Alabama at Birmingham
Co-authored papers 2
Mark J Routbort
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Jake Y Chen
Co-authored papers 2
Jan O Korbel
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Tobias Rausch
University of Heidelberg
Co-authored papers 2
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 2
Zeynep Coban Akdemir
Baylor College of Medicine
Co-authored papers 2
Anna Y Lee
Ontario Institute for Cancer Research
Co-authored papers 2
Shane McCarthy
Wellcome Sanger Institute
Co-authored papers 2
Jonathan Sebat
University of California San Diego
Co-authored papers 2
Pengfei Liu
Co-authored papers 2
Kai Ye
Co-authored papers 2
Shalini N Jhangiani
Baylor College of Medicine
Co-authored papers 2
Evan E Eichler
University of Washington
Co-authored papers 2
Ryan E Mills
University of Michigan Medical School ann arbor
Co-authored papers 2
Oliver Stegle
Wellcome Sanger Institute
Co-authored papers 2
Release 1.2