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Author Details

Silvia Coma
Boston Children's Hospital and Dana-Farber Cancer Institute
2002
21
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36882482Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib.Sci Rep2023
37858338High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.Cell Rep Med2023
35084470PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.Blood2022
35666806Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression.Mol Cancer Ther2022
36465553Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.Nat Catal2022
34389658Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for <i>GNAQ</i>-Driven Uveal Melanoma.Clin Cancer Res2021
33568347Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for <i>GNAQ</i>-Driven Uveal Melanoma.Clin Cancer Res2021
33786583Synergistic efficacy of the dual PI3K-δ/γ inhibitor duvelisib with the Bcl-2 inhibitor venetoclax in Richter syndrome PDX models.Blood2021
30010674Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.Nat Biotechnol2018
27401346Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.J Exp Med2016
25424831AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation.Angiogenesis2015
26156437Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo.Sci Rep2015
23195957Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein.J Biol Chem2013
23892628GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2.Angiogenesis2013
24023743Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody.PLoS One2013
21610314Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2.Cell Adh Migr2011
20388805Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F.Cancer Res2010
19261618Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes.J Biol Chem2009
16396621Strand displacement of double-stranded DNA by triplex-forming antiparallel purine-hairpins.Oligonucleotides2005
15294074Use of siRNAs and antisense oligonucleotides against survivin RNA to inhibit steps leading to tumor angiogenesis.Oligonucleotides2004
12477281Development and effects of immunoliposomes carrying an antisense oligonucleotide against DHFR RNA and directed toward human breast cancer cells overexpressing HER2.Antisense Nucleic Acid Drug Dev2002
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Collaborators

Jonathan A Pachter
Laufer Center for Physical and Quantitative Biology, Stony Brook University
Co-authored papers 6
Kyle Ford
University of California San Diego
Co-authored papers 4
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Co-authored papers 3
Robert Saddawi-Konefka
Moores Cancer Center, University of California San Diego
Co-authored papers 3
Simone Lubrano
Moores Cancer Center, University of California
Co-authored papers 3
Nadia Arang
Moores Cancer Center, University of California San Diego
Co-authored papers 3
Andrew E Aplin
Thomas Jefferson University
Co-authored papers 2
Ayush Kishore
Moores Cancer Center, University of California San Diego
Co-authored papers 2
Chi-Ping Day
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Manoela Tiago
Thomas Jefferson University
Co-authored papers 2
Takami Sato
Sidney Kimmel Cancer Center, Thomas Jefferson University
Co-authored papers 2
Glenn Merlino
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 2
Justine S Paradis
Moores Cancer Center, University of California San Diego
Co-authored papers 2
Xingyu Wu
Moores Cancer Center, University of California San Diego
Co-authored papers 2
David M Briscoe
Boston Children's Hospital
Co-authored papers 1
Damiano Cosimo Rigiracciolo
European Institute of Oncology IRCCS
Co-authored papers 1
Jing Yang
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Monica Acosta
Co-authored papers 1
Amy J Wagers
Joslin Diabetes Center
Co-authored papers 1
Antonio Iavarone
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 1
Farhoud Faraji
University of California San Diego Health
Co-authored papers 1
Monica Acosta
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Yuan Zhou
Co-authored papers 1
Anna Lasorella
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 1
Sydney I Ramirez
Moores Cancer Center, University of California San Diego
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Frances A Tosto
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George Q Daley
Boston Children's Hospital, Harvard Medical School
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Release 1.2