Author details

Full Name

Jason Ernst

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37493860	Pan-primate studies of age and sex.	Geroscience	2023
36342196	A framework for group-wise summarization and comparison of chromatin state annotations.		2023
37679846	ChromGene: gene-based modeling of epigenomic data.		2023
37674040	Author Correction: Universal DNA methylation age across mammalian tissues.	Nat Aging	2023
37563227	Universal DNA methylation age across mammalian tissues.	Nat Aging	2023
37561875	DNA methylation networks underlying mammalian traits.	Science	2023
36638270	STAT3 promotes a youthful epigenetic state in articular chondrocytes.	Aging Cell	2023
37370147	Universal chromatin state annotation of the mouse genome.		2023
37503240	Integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types.		2023
34591235	Epigenetic clock and methylation studies in vervet monkeys.	Geroscience	2022
34991667	Universal annotation of the human genome through integration of over a thousand epigenomic datasets.		2022
35145108	A mammalian methylation array for profiling methylation levels at conserved sequences.	Nat Commun	2022
34532708	Correction to 'ConsHMM Atlas: conservation state annotations for major genomes and human genetic variation'.	NAR Genomics and Bioinformatics	2021
33958799	Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.	Nature Medicine	2021
33941776	Learning a genome-wide score of human-mouse conservation at the functional genomics level.	Nature Communications	2021
34083758	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome.	Communications Biology	2021
34988079	Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation.	Front Cell Dev Biol	2021
34568830	Marginal Contribution Feature Importance - an Axiomatic Approach for Explaining Data.		2021
34487267	Epigenetic clock and methylation studies in the rhesus macaque.	Geroscience	2021
33268804	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations.	Nature Communications	2020
31742318	An integrative approach for fine-mapping chromatin interactions.		2020
33543124	ConsHMM Atlas: conservation state annotations for major genomes and human genetic variation.	NAR Genomics and Bioinformatics	2020
32699851	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome.		2020
31286065	Systematic discovery of conservation states for single-nucleotide annotation of the human genome.	Communications Biology	2019
31834882	Leveraging allelic imbalance to refine fine-mapping for eQTL studies.	PLoS Genet	2019
29467410	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.	Nat Commun	2018
29973585	Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.	Nat Commun	2018
30107810	Investigating enhancer evolution with massively parallel reporter assays.		2018
30097049	ChromTime: modeling spatio-temporal dynamics of chromatin marks.		2018
30194383	Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes.	Nat Commun	2018
30140049	Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.	Nat Commun	2018
30140000	Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.	Nat Commun	2018
28111071	Cooperative Binding of Transcription Factors Orchestrates Reprogramming.	Cell	2017
28445736	Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression.	Cell Rep	2017
29058599	Evidence of reduced recombination rate in human regulatory domains.	Genome Biol	2017
29120462	Chromatin-state discovery and genome annotation with ChromHMM.	Nat Protoc	2017
27495157	Circadian variation of the pancreatic islet transcriptome.	Physiological Genomics	2016
27307612	Using genomic annotations increases statistical power to detect eGenes.		2016
27760116	Chromosome conformation elucidates regulatory relationships in developing human brain.	Nature	2016
27701403	Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions.	Nat Biotechnol	2016
26450788	Dual Roles of RNF2 in Melanoma Progression.	Cancer Discov	2015
25693563	Integrative analysis of 111 reference human epigenomes.	Nature	2015
25690853	Large-scale imputation of epigenomic datasets for systematic annotation of diverse human tissues.	Nat Biotechnol	2015
25122670	Distinct and predictive histone lysine acetylation patterns at promoters, enhancers, and gene bodies.	G3 (Bethesda)	2014
25129075	Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.	Nat Neurosci	2014
23512712	Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay.	Genome Res	2013
24170599	Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps.	Genome Res	2013
24035354	Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization.		2013
23595227	Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types.	Genome Res	2013
23526891	RFECS: a random-forest based algorithm for enhancer identification from chromatin state.	PLoS Comput Biol	2013