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Author Details

Wendy Dubois
Center for Cancer Research, National Cancer Institute
2000
47
23
PMIDPaper TitleJournal TitlePublished Year
36799863Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer.Cancer Res2023
37491298SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma.Cell Biosci2023
37356470Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma.Cancer Lett2023
34964999Conditional deletion of mTOR discloses its essential role in early B-cell development.Mol Carcinog2022
35727842Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence.PLoS Genet2022
33945523CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer.PLoS Genet2021
34876184WDR26 and MTF2 are therapeutic targets in multiple myeloma.J Hematol Oncol2021
33950553Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress.EMBO Rep2021
32923678Mouse tumor susceptibility genes identify drug combinations for multiple myeloma.J Cancer Metastasis Treat2020
32747423Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis.Mol Cancer Ther2020
33005010FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells.Commun Biol2020
32858886Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression.Int J Mol Sci2020
31548308The transcription factor MZF1 differentially regulates murine <i>Mtor</i> promoter variants linked to tumor susceptibility.J Biol Chem2019
303496473'<i>Igh</i> enhancers hs3b/hs4 are dispensable for <i>Myc</i> deregulation in mouse plasmacytomas with T(12;15) translocations.Oncotarget2018
28522584Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.Mol Cancer Ther2017
29133782mTOR intersects antibody-inducing signals from TACI in marginal zone B cells.Nat Commun2017
29259245ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells.Sci Rep2017
28803781Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.Mol Cell2017
28552607cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma.Stem Cell Reports2017
27330189MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.Sci Signal2016
25524638p53 loss increases the osteogenic differentiation of bone marrow stromal cells.Stem Cells2015
25936916An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells.Cell Stem Cell2015
25193464Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.Cancer Lett2014
25483777B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.Cell2014
23535297Rap2b, a novel p53 target, regulates p53-mediated pro-survival function.Cell Cycle2013
23858034B cell-specific deficiencies in mTOR limit humoral immune responses.J Immunol2013
23994476Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.Cell Rep2013
23707059A genome-wide map of CTCF multivalency redefines the CTCF code.Cell Rep2013
22147894Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia.Blood2012
22711821Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.Proc Natl Acad Sci U S A2012
22869734Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus.Proc Natl Acad Sci U S A2012
22387025Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells.Mol Cell2012
21079150Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.Blood2011
22053105mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.Blood2011
20018915IL-6 and MYC collaborate in plasma cell tumor formation in mice.Blood2010
20605486Regulation of microRNA expression and abundance during lymphopoiesis.Immunity2010
19654412Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility.Blood2009
18678733AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development.J Exp Med2008
18025197Transgenic expression of Bcl-xL or Bcl-2 by murine B cells enhances the in vivo antipolysaccharide, but not antiprotein, response to intact Streptococcus pneumoniae.J Immunol2007
17998390AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements.J Exp Med2007
16759389CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms.Mol Cancer2006
16140930Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice.Cancer Res2005
14578173Susceptibility to anthrax lethal toxin is controlled by three linked quantitative trait loci.Am J Pathol2003
14634209Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.Proc Natl Acad Sci U S A2003
11113205Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility.Mol Cell Biol2001
11125484Myeloma proteins that bind Hsp65 (GroEL) are polyreactive and are found in high incidence in pristine induced plasmacytomas.Curr Top Microbiol Immunol2000
11275262Double producers of kappa and lambda define a subset of B cells in mouse plasmacytomas.Mol Immunol2000
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Collaborators

Center for Cancer Research, National Cancer Institute
Co-authored papers 19
School of Public Health, Guizhou Medical University
Co-authored papers 15
National Cancer Institute, National Institutes of Health
Co-authored papers 7
Center for Cancer Research, National Cancer Institute
Co-authored papers 5
Center for Cancer Research, National Cancer Institute
Co-authored papers 5
Centers for Disease Control and Prevention
Co-authored papers 4
College of Life Science, Zhejiang University
Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 3
National Heart Lung and Blood Institute Division of Intramural Research
Co-authored papers 2
Leidos Biomedical Research Inc.
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
and Blood Institute, National Institutes of Health
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
National Cancer Institute, 9609 Medical Center Drive
Co-authored papers 2
Science Applications International Corporation/Frederick
Co-authored papers 2
Co-authored papers 1
National Center for Advancing Translational Sciences
Co-authored papers 1
Co-authored papers 1
Industrial Technology Research Institute
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Louisiana State University
Co-authored papers 1
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
National Institute of Arthritis, National Institutes of Health
Co-authored papers 1
Genentech Inc.
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