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Author Details

Pedro Aza-Blanc
Sanford-Burnham-Prebys Medical Discovery Institute
1993
43
29
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35840561The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer.Cell Death Dis2022
33210294Targeting USP13-mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in non-small cell lung cancer.Int J Cancer2021
34874009Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology.Elife2021
34556638TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells.Cell Death Dis2021
34462276Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance.Cancer Res2021
30807999Withdrawal: <i>Dm1</i>-MMP, a matrix metalloproteinase from <i>Drosophila</i> with a potential role in extracellular matrix remodeling during neural development.J Biol Chem2019
26971564Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation.Elife2016
27698189miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3.Cancer Res2016
27829216ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer.Oncotarget2016
27453043A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.Mol Cell2016
27033521Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.Biochim Biophys Acta2016
25749035Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma.Oncotarget2015
26279575Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade.Cell Rep2015
26091350Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass.Oncotarget2015
26026149Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome.Elife2015
25660024Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ.Cell Rep2015
25790448PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines.PLoS One2015
24448648Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.Sci Signal2014
25277522An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability.Nat Commun2014
23035722Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.Pigment Cell Melanoma Res2013
23608534Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.Mol Cell Biol2013
22578813Translational homeostasis via the mRNA cap-binding protein, eIF4E.Mol Cell2012
23024808Functional specialization in proline biosynthesis of melanoma.PLoS One2012
21592316Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways.Pigment Cell Melanoma Res2011
20071576Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen.J Virol2010
20639500Identification of MicroRNAs that control lipid droplet formation and growth in hepatocytes via high-content screening.J Biomol Screen2010
20393563Functional genomic screen for modulators of ciliogenesis and cilium length.Nature2010
17532518PTPome-wide functional RNA interference screening methods.Methods2007
16141075A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.Science2005
15517021RNAi and HTS: exploring cancer by systematic loss-of-function.Oncogene2004
15356269Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.Mol Biol Cell2004
14527409Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening.Mol Cell2003
14563124Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi.Semin Cancer Biol2003
10964925Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development.J Biol Chem2000
10983993Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc.Mol Cell2000
10976059Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.Development2000
10529809Ci: a complex transducer of the hedgehog signal.Trends Genet1999
10329730The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription.J Biol Chem1999
9215627Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor.Cell1997
7635972Congenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1.J Clin Invest1995
8589688A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?Hum Mol Genet1995
7748495Characterization of placental transcriptional activation of the human gene for P450scc.DNA Cell Biol1995
8264661Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity.Mol Endocrinol1993
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Collaborators

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University of California
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Co-authored papers 3
Chugai Pharmaceutical Co.
Co-authored papers 3
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 3
Soonchunhyang University College of Medicine, Bucheon Hospital
Co-authored papers 3
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Co-authored papers 3
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 2
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Cellstan-Immunoquant Inc.
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Rady Children's Institute for Genomic Medicine, University of California
Co-authored papers 2
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Radboud University Medical Center
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Fondazione IRCCS Istituto Neurologico Carlo Besta
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Leiden University Medical Center
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The Wistar Institute
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Amgen Inc.
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American University of Beirut Medical Center
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