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Author Details
Full Name
Pedro Aza-Blanc
Affiliation
Sanford-Burnham-Prebys Medical Discovery Institute
ORCID
Career Start Year
1993
Papers
43
H Index
29
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35840561
The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer.
Cell Death Dis
2022
33210294
Targeting USP13-mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in non-small cell lung cancer.
Int J Cancer
2021
34874009
Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology.
Elife
2021
34556638
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells.
Cell Death Dis
2021
34462276
Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance.
Cancer Res
2021
30807999
Withdrawal: <i>Dm1</i>-MMP, a matrix metalloproteinase from <i>Drosophila</i> with a potential role in extracellular matrix remodeling during neural development.
J Biol Chem
2019
26971564
Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Elife
2016
27698189
miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3.
Cancer Res
2016
27829216
ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer.
Oncotarget
2016
27453043
A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.
Mol Cell
2016
27033521
Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.
Biochim Biophys Acta
2016
25749035
Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma.
Oncotarget
2015
26279575
Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade.
Cell Rep
2015
26091350
Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass.
Oncotarget
2015
26026149
Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome.
Elife
2015
25660024
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ.
Cell Rep
2015
25790448
PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines.
PLoS One
2015
24448648
Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.
Sci Signal
2014
25277522
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability.
Nat Commun
2014
23035722
Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.
Pigment Cell Melanoma Res
2013
23608534
Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.
Mol Cell Biol
2013
22578813
Translational homeostasis via the mRNA cap-binding protein, eIF4E.
Mol Cell
2012
23024808
Functional specialization in proline biosynthesis of melanoma.
PLoS One
2012
21592316
Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways.
Pigment Cell Melanoma Res
2011
20071576
Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen.
J Virol
2010
20639500
Identification of MicroRNAs that control lipid droplet formation and growth in hepatocytes via high-content screening.
J Biomol Screen
2010
20393563
Functional genomic screen for modulators of ciliogenesis and cilium length.
Nature
2010
17532518
PTPome-wide functional RNA interference screening methods.
Methods
2007
16141075
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.
Science
2005
15517021
RNAi and HTS: exploring cancer by systematic loss-of-function.
Oncogene
2004
15356269
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
Mol Biol Cell
2004
14527409
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening.
Mol Cell
2003
14563124
Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi.
Semin Cancer Biol
2003
10964925
Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development.
J Biol Chem
2000
10983993
Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc.
Mol Cell
2000
10976059
Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.
Development
2000
10529809
Ci: a complex transducer of the hedgehog signal.
Trends Genet
1999
10329730
The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription.
J Biol Chem
1999
9215627
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor.
Cell
1997
7635972
Congenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1.
J Clin Invest
1995
8589688
A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?
Hum Mol Genet
1995
7748495
Characterization of placental transcriptional activation of the human gene for P450scc.
DNA Cell Biol
1995
8264661
Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity.
Mol Endocrinol
1993
1 - 43 of 43
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