Author details

Full Name

Choong Yong Ung

Affiliation

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37786979	Vertical Transmission of SARS-CoV-2-Specific Antibodies and Cytokine Profiles in Pregnancy.	J Infect Dis	2024
36866271	Manifold epigenetics: A conceptual model that guides engineering strategies to improve whole-body regenerative health.		2023
37461664	Ethnicity is not biology: retinal pigment score to evaluate biological variability from ophthalmic imaging using machine learning.	medRxiv	2023
37371475	SPIN-AI: A Deep Learning Model That Identifies Spatially Predictive Genes.		2023
34600126	Manifold medicine: A schema that expands treatment dimensionality.	Drug Discov Today	2022
35911770	A Knowledge-Based Discovery Approach Couples Artificial Neural Networks With Weight Engineering to Uncover Immune-Related Processes Underpinning Clinical Traits of Breast Cancer.	Frontiers in Immunology	2022
35832612	Gene utility recapitulates chromosomal aberrancies in advanced stage neuroblastoma.	Computational and Structural Biotechnology Journal	2022
35359437	Uncovering Pharmacological Opportunities for Cancer Stem Cells-A Systems Biology View.	Front Cell Dev Biol	2022
34876496	De novo individualized disease modules reveal the synthetic penetrance of genes and inform personalized treatment regimens.	Genome Research	2022
33842927	Machine Learning and Systems Biology Approaches to Characterize Dosage-Based Gene Dependencies in Cancer Cells.		2021
33602789	GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.	Cancer Res	2021
34356114	The Trifecta of Single-Cell, Systems-Biology, and Machine-Learning Approaches.	Genes (Basel)	2021
34045642	Modular network mechanism of CCN1-associated resistance to HSV-1-derived oncolytic immunovirotherapies for glioblastomas.	Scientific Reports	2021
31875547	Dysregulation of RNA Splicing in Tauopathies.	Cell Reports	2019
31114928	Regulostat Inferelator: a novel network biology platform to uncover molecular devices that predetermine cellular response phenotypes.	Nucleic Acids Research	2019
29273772	Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.	Nature Neuroscience	2018
28329685	Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation.	Cell Rep	2017
28867147	LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.	Cancer Cell	2017
28765560	Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks.	Scientific Reports	2017
26975659	NetDecoder: a network biology platform that decodes context-specific biological networks and gene activities.	Nucleic Acids Research	2016
28035989	Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology.	International Journal of Molecular Sciences	2016
27841317	A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.	Sci Rep	2016
25867597	Mosaic zebrafish transgenesis for functional genomic analysis of candidate cooperative genes in tumor pathogenesis.	Journal of Visualized Experiments	2015
24845512	The evolutionary strata of DARPP-32 tail implicates hierarchical functional expansion in higher vertebrates.		2014
23457601	Inverted expression profiles of sex-biased genes in response to toxicant perturbations and diseases.	PLoS One	2013
23791553	Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses.		2013
22047996	Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: histological, gene set enrichment and expression analyses.		2012
23272195	Toxicogenomic analysis suggests chemical-induced sexual dimorphism in the expression of metabolic genes in zebrafish liver.	PLoS One	2012
22278128	Metabolic network analysis revealed distinct routes of deletion effects between essential and non-essential genes.	Molecular BioSystems	2012
22140468	Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver.	PLoS One	2011
22194820	Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish.	PLoS ONE	2011
19569201	Identification of small molecule aggregators from large compound libraries by support vector machines.	Journal of Computational Chemistry	2010
20384484	Incorporating zebrafish omics into chemical biology and toxicology.		2010
20353558	Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation.	BMC Genomics	2010
19074159	Simulation of crosstalk between small GTPase RhoA and EGFR-ERK signaling pathway via MEKK1.		2009
19916844	Comparative transcriptome analyses revealed conserved biological and transcription factor target modules between the zebrafish and human tumors.		2009
19551902	Pathway sensitivity analysis for detecting pro-proliferation activities of oncogenes and tumor suppressors of epidermal growth factor receptor-extracellular signal-regulated protein kinase pathway at altered protein levels.	Cancer	2009
18505685	Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk.	FEBS Letters	2008
16884871	Usefulness of traditionally defined herbal properties for distinguishing prescriptions of traditional Chinese medicine from non-prescription recipes.	Journal of Ethnopharmacology	2007
16563508	Computer prediction of allergen proteins from sequence-derived protein structural and physicochemical properties.	Molecular Immunology	2007
17786989	Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins.	Journal of Pharmaceutical Sciences	2007
17404245	AAIR: antibody antigen information resource.	Journal of Immunology	2007
17267151	Are herb-pairs of traditional Chinese medicine distinguishable from others? Pattern analysis and artificial intelligence classification study of traditionally defined herbal properties.	Journal of Ethnopharmacology	2007
17266544	Computer prediction of cardiovascular and hematological agents by statistical learning methods.	Cardiovascular and Hematological Agents in Medicinal Chemistry	2007
17003167	In silico prediction of pregnane X receptor activators by machine learning approaches.	Molecular Pharmacology	2007
16918241	Classification of a diverse set of Tetrahymena pyriformis toxicity chemical compounds from molecular descriptors by statistical learning methods.	Chemical Research in Toxicology	2006
16613581	Prediction of compounds with specific pharmacodynamic, pharmacokinetic or toxicological property by statistical learning methods.	Mini-Reviews in Medicinal Chemistry	2006
16497524	Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	Journal of Molecular Graphics and Modelling	2006
17088869	Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation.	British Journal of Pharmacology	2006
15962942	Prediction of genotoxicity of chemical compounds by statistical learning methods.	Chemical Research in Toxicology	2005