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Author Details
Full Name
Michael K Rosen
Affiliation
UT Southwestern Medical Center
ORCID
Career Start Year
1990
Papers
130
H Index
68
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36972455
Quantitative reconstitution of yeast RNA processing bodies.
Proc Natl Acad Sci U S A
2023
37488172
Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct.
Sci Rep
2023
37126554
Coupling of protein condensates to ordered lipid domains determines functional membrane organization.
Sci Adv
2023
37214845
Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct.
bioRxiv
2023
34772789
Using quantitative reconstitution to investigate multicomponent condensates.
RNA
2022
35922507
A mitotic chromatin phase transition prevents perforation by microtubules.
Nature
2022
35332323
Bound nucleotide can control the dynamic architecture of monomeric actin.
Nat Struct Mol Biol
2022
35049497
Synergistic phase separation of two pathways promotes integrin clustering and nascent adhesion formation.
Elife
2022
34986150
Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity.
PLoS One
2022
33395293
Structure-Function Properties in Disordered Condensates.
J Phys Chem B
2021
33692102
Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin.
Sci Adv
2021
34035521
Mechanistic dissection of increased enzymatic rate in a phase-separated compartment.
Nat Chem Biol
2021
33973848
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.
Elife
2021
33169001
A framework for understanding the functions of biomolecular condensates across scales.
Nat Rev Mol Cell Biol
2021
32451441
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein.
Nat Cell Biol
2020
32474299
Karyopherins and condensates.
Curr Opin Cell Biol
2020
32553117
A quantitative inventory of yeast P body proteins reveals principles of composition and specificity.
Elife
2020
30846599
Stoichiometry controls activity of phase-separated clusters of actin signaling proteins.
Science
2019
31268421
A composition-dependent molecular clutch between T cell signaling condensates and actin.
Elife
2019
31599693
Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction.
Mol Biol Cell
2019
31543265
Organization of Chromatin by Intrinsic and Regulated Phase Separation.
Cell
2019
31541396
Improved strategy for isoleucine <sup>1</sup>H/<sup>13</sup>C methyl labeling in Pichia pastoris.
J Biomol NMR
2019
30951647
Regulation of Transmembrane Signaling by Phase Separation.
Annu Rev Biophys
2019
29425497
Intrinsically Disordered Regions Can Contribute Promiscuous Interactions to RNP Granule Assembly.
Cell Rep
2018
30099028
Who's In and Who's Out-Compositional Control of Biomolecular Condensates.
J Mol Biol
2018
29677513
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell
2018
28522495
ATP controls the crowd.
Science
2017
28255696
Reconstitution of TCR Signaling Using Supported Lipid Bilayers.
Methods Mol Biol
2017
28225081
Biomolecular condensates: organizers of cellular biochemistry.
Nat Rev Mol Cell Biol
2017
29182244
Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation.
J Am Chem Soc
2017
28949297
Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites.
Elife
2017
29091028
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins.
Elife
2017
28924037
Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs.
J Biol Chem
2017
26894386
Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris.
J Biomol NMR
2016
27871362
Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster.
Elife
2016
27827364
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.
Nat Commun
2016
27392146
Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.
Mol Cell
2016
27374333
Compositional Control of Phase-Separated Cellular Bodies.
Cell
2016
27459345
Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives.
J Am Chem Soc
2016
26903538
Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation.
J Cell Biol
2016
27056844
Phase separation of signaling molecules promotes T cell receptor signal transduction.
Science
2016
27002172
Correction: Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation.
J Cell Biol
2016
26947396
Data publication with the structural biology data grid supports live analysis.
Nat Commun
2016
26025061
Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris.
J Biomol NMR
2015
26412307
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins.
Mol Cell
2015
26553976
Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck.
Proc Natl Acad Sci U S A
2015
24439376
The WAVE regulatory complex links diverse receptors to the actin cytoskeleton.
Cell
2014
28903028
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation.
Curr Biol
2014
25203209
Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton.
Dev Cell
2014
25321392
Phase transitions of multivalent proteins can promote clustering of membrane receptors.
Elife
2014
1 - 50 of 130
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