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Author Details

Michael J Adam
University of Washington School of Medicine
1984
84
38
PMIDPaper TitleJournal TitlePublished Year
37503136The Medical Action Ontology: A Tool for Annotating and Analyzing Treatments and Clinical Management of Human Disease.medRxiv2023
37963467The Medical Action Ontology: A tool for annotating and analyzing treatments and clinical management of human disease.Med2023
29456161The effect of LRRK2 mutations on the cholinergic system in manifest and premanifest stages of Parkinson's disease: a cross-sectional PET study.Lancet Neurol2018
28336296Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies.Lancet Neurol2017
26727049Overexpression of HER-2 in MDA-MB-435/LCC6 Tumours is Associated with Higher Metabolic Activity and Lower Energy Stress.Sci Rep2016
26652124Novel "bi-modal" H<sub>2</sub>dedpa derivatives for radio- and fluorescence imaging.J Inorg Biochem2016
27623550Facile synthesis and <sup>18</sup>F-radiolabeling of α<sub>4</sub>β<sub>1</sub>-specific LLP2A-aryltrifluoroborate peptidomimetic conjugates.Bioorg Med Chem Lett2016
27419360A comparative evaluation of the chelators H4octapa and CHX-A⿳-DTPA with the therapeutic radiometal (90)Y.Nucl Med Biol2016
27161975Evaluation of H2CHXdedpa, H2dedpa- and H2CHXdedpa-N,N'-propyl-2-NI ligands for (64)Cu(ii) radiopharmaceuticals.Dalton Trans2016
25621728H2CHXdedpa and H4CHXoctapa-chiral acyclic chelating ligands for (67/68)Ga and (111)In radiopharmaceuticals.Inorg Chem2015
26264926Production of Y-86 and other radiometals for research purposes using a solution target system.Nucl Med Biol2015
25833342[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.J Cereb Blood Flow Metab2015
25928800Nitroimidazole-Containing H2dedpa and H2CHXdedpa Derivatives as Potential PET Imaging Agents of Hypoxia with (68)Ga.Inorg Chem2015
24104523H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu.Dalton Trans2014
25192223What a difference a carbon makes: Hâ¿¿octapa vs Hâ¿¿C3octapa, ligands for In-111 and Lu-177 radiochemistry.Inorg Chem2014
24676528Modular syntheses of H⿿octapa and H⿿dedpa, and yttrium coordination chemistry relevant to ⁸⁶Y/⁹⁰Y radiopharmaceuticals.Dalton Trans2014
23327489Structural characteristics of chloroquine-bridged ferrocenophane analogues of ferroquine may obviate malaria drug-resistance mechanisms.J Med Chem2013
23901833H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy.J Am Chem Soc2013
23315972Stoichiometric leverage: rapid 18F-aryltrifluoroborate radiosynthesis at high specific activity for click conjugation.Angew Chem Int Ed Engl2013
223780311,2-disubstituted ferrocenyl carbohydrate chloroquine conjugates as potential antimalarial agents.Dalton Trans2012
23106422H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu.Inorg Chem2012
22540281H4octapa: an acyclic chelator for 111In radiopharmaceuticals.J Am Chem Soc2012
22583103Evaluation of the H2)dedpa scaffold and its cRGDyK conjugates for labeling with 64Cu.Inorg Chem2012
22381779RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga.Nucl Med Biol2012
21308135One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co.Dalton Trans2011
21831655New Ga derivatives of the H2dedpa scaffold with improved clearance and persistent heart uptake.Nucl Med Biol2011
21567141Novel use of F-DOPA PET/CT imaging in a child with paraganglioma/pheochromocytoma syndrome.Pediatr Radiol2011
20153207Cationic technetium and rhenium complexes with pendant carbohydrates.Appl Radiat Isot2010
20729277Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.Cancer Res2010
20958034Acyclic chelate with ideal properties for (68)Ga PET imaging agent elaboration.J Am Chem Soc2010
20513859Effect of electroconvulsive therapy on brain 5-HT(2) receptors in major depression.Br J Psychiatry2010
20534487Imaging of enzyme replacement therapy using PET.Proc Natl Acad Sci U S A2010
19341277Design, synthesis, and imaging of small amphiphilic rhenium and (99m)technetium tricarbonyl complexes.Bioconjug Chem2009
20449200Long-chain rhenium and technetium glucosamine conjugates.Dalton Trans2009
20449199Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)3]+ core (M = Re, Tc).Dalton Trans2009
20183579Labeling of an antisense oligonucleotide with [(18)F]FPy5yne.Nucleosides Nucleotides Nucleic Acids2009
18189350Pyridine-tert-nitrogen-phenol ligands: N,N,O-Type tripodal chelates for the [M(CO)3]+ core (M = Re, Tc).Inorg Chem2008
19010842Irinophore C, a novel nanoformulation of irinotecan, alters tumor vascular function and enhances the distribution of 5-fluorouracil and doxorubicin.Clin Cancer Res2008
18489162Substituent effects on aryltrifluoroborate solvolysis in water: implications for Suzuki-Miyaura coupling and the design of stable (18)F-labeled aryltrifluoroborates for use in PET imaging.J Org Chem2008
18700764Toward [18F]-labeled aryltrifluoroborate radiotracers: in vivo positron emission tomography imaging of stable aryltrifluoroborate clearance in mice.J Am Chem Soc2008
1766619055Cobalt complexes with pendant carbohydrates as potential PET imaging agents.Appl Radiat Isot2007
16984143Carbohydrate-appended 3-hydroxy-4-pyridinone complexes of the [M(CO)3]+ core (M = Re, 99mTc, 186Re).Bioconjug Chem2006
16999442Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates.Inorg Chem2006
16903757Glucosamine conjugates of tricarbonylcyclopentadienyl rhenium(I) and technetium(I) cores.Inorg Chem2006
15702173A glucosamine-dipicolylamine conjugate of 99mTc(I) and 186Re(I) for use in imaging and therapy.Dalton Trans2005
16225561A positron emission tomography study of the effects of treatment with valproate on brain 5-HT2A receptors in acute mania.Bipolar Disord2005
16173707Arylfluoroborates and alkylfluorosilicates as potential PET imaging agents: high-yielding aqueous biomolecular 18F-labeling.J Am Chem Soc2005
16287260Carbohydrate-bearing 3-hydroxy-4-pyridinonato complexes of gallium(III) and indium(III).Bioconjug Chem2005
15819555Carbohydrate-appended 2,2'-dipicolylamine metal complexes as potential imaging agents.Inorg Chem2005
15672179Radiohalogens for imaging and therapy.Chem Soc Rev2005
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Collaborators

University of British Columbia
Co-authored papers 5
University of California san francisco
Co-authored papers 2
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 2
Center for the Science of Therapeutics, Broad Institute of MIT and Harvard
Co-authored papers 2
University of Cambridge, Heart and Lung Research Institute
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 2
International Society for Biocuration, Lawrence Berkeley National Laboratory, University of Edinburgh, University of Edinburgh School of Biological Sciences
Co-authored papers 2
Biosanitary Research Institute of Granada (ibs.GRANADA)
Co-authored papers 2
Co-authored papers 2
Critical Path Institute
Co-authored papers 2
Vall d'Hebron University Hospital and VHIR (Euro-NMD
Co-authored papers 2
Universitatsklinikum des Saarlandes UKS
Co-authored papers 2
Co-authored papers 2
Children's Hospital of Eastern Ontario Research Institute
Co-authored papers 2
University of British Columbia
Co-authored papers 2
Technical University of Denmark
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Children's Hospital of Eastern Ontario Research Institute
Co-authored papers 2
American Medical Informatics Association, Oregon Health and Science University, Oregon State University, University of Colorado Anschutz Medical Campus, University of North Carolina at Chapel Hill, University of Wisconsin-Madison
Co-authored papers 2
Co-authored papers 2
Institute of Epidemiology, Research Unit Molecular Epidemiology
Co-authored papers 2
Co-authored papers 1
Oregon State University,Corvallis,OR,United States.
Co-authored papers 1
Oregon State University
Co-authored papers 1
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Blavatnik Institute, Harvard Medical School
Co-authored papers 1
Co-authored papers 1