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Author Details

Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
1992
197
47
PMIDPaper TitleJournal TitlePublished Year
36939350Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control.J Virol2023
37095531High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.J Exp Clin Cancer Res2023
34729560A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.bioRxiv2022
35511749A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors.Mol Cancer Ther2022
35696646Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.J Med Chem2022
35754433Teaching principles of translational science to a broad scientific audience using a case study approach: A pilot course from the National Center for Advancing Translational Sciences.J Clin Transl Sci2022
36333465Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.Commun Biol2022
36065186Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.iScience2022
36253497Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells.Sci Rep2022
35041689A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.PLoS One2022
35092840A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.SLAS Discov2022
35239443Discovery of a functionally selective ghrelin receptor (GHSR<sub>1a</sub>) ligand for modulating brain dopamine.Proc Natl Acad Sci U S A2022
35166694Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform.Biofabrication2022
34189531Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection.bioRxiv2021
33742123Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer.Oncogene2021
33731741A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.Sci Rep2021
33860201Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening.ACS Pharmacol Transl Sci2021
34911940Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.Nat Commun2021
34439084The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis.Cancers (Basel)2021
34378323Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.EMBO Mol Med2021
34184537Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.J Med Chem2021
34075120Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells.Sci Rep2021
34013274Modeling SARS-CoV-2 and Influenza Infections and Antiviral Treatments in Human Lung Epithelial Tissue Equivalents.bioRxiv2021
34269079Operationalizing the Use of Biofabricated Tissue Models as Preclinical Screening Platforms for Drug Discovery and Development.SLAS Discov2021
34010142Pharmacological activation of STING blocks SARS-CoV-2 infection.Sci Immunol2021
34264955Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.PLoS One2021
31562255Quantitative High-Throughput Screening Using an Organotypic Model Identifies Compounds that Inhibit Ovarian Cancer Metastasis.Mol Cancer Ther2020
32059197A biofabricated vascularized skin model of atopic dermatitis for preclinical studies.Biofabrication2020
32051227Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.Sci Transl Med2020
31658853A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells.SLAS Discov2020
33334024Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer.Cancers (Basel)2020
32575908Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model.Cancers (Basel)2020
32908007Therapeutic responses to <i>Roseomonas mucosa</i> in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair.Sci Transl Med2020
32676161A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue.Oncotarget2020
32642733KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors.Neurooncol Adv2020
32154236Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.Front Bioeng Biotechnol2020
32111885Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells.Sci Rep2020
32231230Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.Sci Rep2020
32128386Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.Sci Adv2020
32511420An OpenData portal to share COVID-19 drug repurposing data in real time.bioRxiv2020
32342685Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D<sub>3</sub> Dopamine Receptor Agonist.J Med Chem2020
32191456Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.J Med Chem2020
30289729Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.SLAS Technol2019
31748226Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening.Sci Transl Med2019
31825310Agonist-specific voltage-dependent gating of lysosomal two-pore Na<sup>+</sup> channels.Elife2019
316543903D Engineering of Ocular Tissues for Disease Modeling and Drug Testing.Adv Exp Med Biol2019
30075192In vitro and in vivo translational models for rare liver diseases.Biochim Biophys Acta Mol Basis Dis2019
30071313Translational in vitro research: integrating 3D drug discovery and development processes into the drug development pipeline.Drug Discov Today2019
31395684Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.Mol Cancer Ther2019
31632920Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.Front Oncol2019
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Collaborators

Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 57
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Co-authored papers 36
Rajarshi Guha
Vertex Pharmaceuticals
Co-authored papers 35
Xiaohu Zhang
National Center for Advancing Translational Sciences
Co-authored papers 19
Sam Michael
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 14
Ajit Jadhav
Co-authored papers 10
Anton Simeonov
Co-authored papers 10
Amy S Espeseth
Merck & Co., Inc.
Co-authored papers 8
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 7
Udo Rudloff
Center for Cancer Research, National Cancer Institute
Co-authored papers 7
Louis M Staudt
National Cancer Institute, National Institutes of Health
Co-authored papers 5
Ernst Lengyel
University of Chicago
Co-authored papers 5
Michele Ceribelli
National Center for Advancing Translational Sciences
Co-authored papers 5
Yansong Bian
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 4
Javed Khan
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Jack F Shern
Co-authored papers 4
Matthew B Boxer
Co-authored papers 4
Christopher P Austin
St. George's University Medical School
Co-authored papers 4
Zhuyin Li
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 3
Young K Song
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Daria J Hazuda
Merck & Co. Inc.
Co-authored papers 3
Jun S Wei
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Arnulfo Mendoza
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Wenming Xiao
Human Phenome Institute and Shanghai Cancer Center, Fudan University
Co-authored papers 3
Jaishri O Blakeley
Johns Hopkins University
Co-authored papers 3
Michael B Major
Washington University in St. Louis
Co-authored papers 3
Sara Cherry
University of Pennsylvania
Co-authored papers 3
Yaroslav Teper
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
Abisola Abisoye-Ogunniyan
Lawrence Livermore National Laboratory
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Release 1.2