Author details

Full Name

Timothy D Howard

Affiliation

ORCID

Career Start Year

1992

Papers

136

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37005464	Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and European ancestry.	Sci Rep	2023
37326643	Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures.	Pain	2023
36533506	Study of an Educational Telenovela to Teach Genomics among Latino Farmworkers and Nonfarmworkers: Lessons Learned.	Prog Community Health Partnersh	2022
36313967	Transcriptional profiles in olfactory pathway-associated brain regions of African green monkeys: Associations with age and Alzheimer's disease neuropathology.	Alzheimer's and Dementia: Translational Research and Clinical Interventions	2022
35768168	Social Factors, Epigenomics and Lupus in African American Women (SELA) Study: protocol for an observational mechanistic study examining the interplay of multiple individual and social factors on lupus outcomes in a health disparity population.	Lupus Sci Med	2022
35704681	Gut dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus.	Gut Microbes	2022
35547202	Multi-Site Observational Study to Assess Biomarkers for Susceptibility or Resilience to Chronic Pain: The Acute to Chronic Pain Signatures (A2CPS) Study Protocol.	Front Med (Lausanne)	2022
35468233	Mental models about heredity among immigrant Latinx adults with limited education from Mexico and Central America.	J Genet Couns	2022
37397545	The modifying influence of HLA class II DQB1â¿¿06:02 on the <i>Streptococcus</i> and clinical phenotype correlation among anti-Ro+ mothers of children with neonatal lupus.	Genes Dis	2022
34946847	Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting.	Genes (Basel)	2021
33469784	Genetic Knowledge and Communication Among Mexican Farmworkers and Non-farmworkers in North Carolina.	J Immigr Minor Health	2021
33876458	Efficiency of whole-exome sequencing in old world and new world primates using human capture reagents.	J Med Primatol	2021
33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Am J Hum Genet	2021
34338633	Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model.	eLife	2021
33233697	"It's Worse to Breathe It Than to Smoke It": Secondhand Smoke Beliefs in a Group of Mexican and Central American Immigrants in the United States.	Int J Environ Res Public Health	2020
31677965	Salivary dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus.	J Autoimmun	2020
32986922	Epigenetic methylation in Eosinophilic Esophagitis: Molecular ageing and novel biomarkers for treatment response.	Clin Exp Allergy	2020
32985521	FADS genetic and metabolomic analyses identify the â¿¿5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids.	Scientific Reports	2020
32928872	Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans.	Diabetes	2020
33084892	Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies.	Nucleic Acids Res	2020
33031749	Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries.	Am J Hum Genet	2020
31161966	Monocyte Polarization is Altered by Total-Body Irradiation in Male Rhesus Macaques: Implications for Delayed Effects of Acute Radiation Exposure.	Radiation Research	2019
31561483	The Need for Multi-Omics Biomarker Signatures in Precision Medicine.	International Journal of Molecular Sciences	2019
30866842	Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review.	BMC Medical Genetics	2019
29590160	Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.	PLoS ONE	2018
28622109	Farmworker and nonfarmworker Latino immigrant men in North Carolina have high levels of specific pesticide urinary metabolites.		2018
29023343	Pesticide Urinary Metabolites Among Latina Farmworkers and Nonfarmworkers in North Carolina.		2018
30076241	CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD<sup>+</sup> Pools.	Mol Cancer Res	2018
29915101	Proteomic Architecture of Human Coronary and Aortic Atherosclerosis.	Circulation	2018
30571375	Estradiol Treatment Initiated Early After Ovariectomy Regulates Myocardial Gene Expression and Inhibits Diastolic Dysfunction in Female Cynomolgus Monkeys: Potential Roles for Calcium Homeostasis and Extracellular Matrix Remodeling.	Journal of the American Heart Association	2018
29636834	Allele-specific methylation in the <i>FADS</i> genomic region in DNA from human saliva, CD4+ cells, and total leukocytes.	Clin Epigenetics	2018
26660317	"He Beat You in the Blood": Knowledge and Beliefs About the Transmission of Traits Among Latinos from Mexico and Central America.	J Immigr Minor Health	2017
28957329	Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster.	PLoS One	2017
28642624	Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.	Sci Rep	2017
28719732	Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.	Arthritis Rheumatol	2017
28583619	The impacts of pesticide and nicotine exposures on functional brain networks in Latino immigrant workers.	NeuroToxicology	2017
28714469	Transancestral mapping and genetic load in systemic lupus erythematosus.	Nat Commun	2017
29367937	Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis.	J Proteom Genom Res	2017
27820757	Organophosphate Pesticide Urinary Metabolites Among Latino Immigrants: North Carolina Farmworkers and Non-farmworkers Compared.		2016
27349971	Changes in DNA methylation over the growing season differ between North Carolina farmworkers and non-farmworkers.	International Archives of Occupational and Environmental Health	2016
27197070	Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer.	Prostate	2016
27006379	Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques.	Cancer Prevention Research	2016
26719535	Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer.	Cancer Research	2016
27158949	Brain Anatomy in Latino Farmworkers Exposed to Pesticides and Nicotine.		2016
26606652	Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.	Arthritis Rheumatol	2016
26377519	Urinary Cotinine Levels Among Latino Tobacco Farmworkers in North Carolina Compared to Latinos Not Employed in Agriculture.	Nicotine and Tobacco Research	2016
26153245	Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.	Diabetes	2015
25738949	Learning Ability as a Function of Practice: Does It Apply to Farmworkers?		2015
25256757	The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome.	Clin Genet	2015
26307030	DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis.	Circ Cardiovasc Genet	2015