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Author Details

Carl Koschmann
University of Michigan-Ann Arbor
2010
77
20
PMIDPaper TitleJournal TitlePublished Year
37723046Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence.Mol Cancer Ther2024
37723046Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence.Mol Cancer Ther2024
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
35605606Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.Neuro Oncol2023
37584601Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.Cancer Discov2023
37647805Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma.Neoplasia2023
37802053TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.Cancer Cell2023
37552989Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid.Cell Rep Med2023
37149933Applying collaborative brain power to pull us out of the dark ages of pediatric neuro-oncology.Neoplasia2023
37145169ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.Cancer Res2023
37398299H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas.bioRxiv2023
37195023ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.Cancer Res2023
36685825Liquid biopsy in pediatric brain tumors.Front Genet2023
36724689Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma.Neoplasia2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
37802053TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.Cancer Cell2023
37552989Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid.Cell Rep Med2023
37584601Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.Cancer Discov2023
37647805Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma.Neoplasia2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
35605606Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.Neuro Oncol2023
37149933Applying collaborative brain power to pull us out of the dark ages of pediatric neuro-oncology.Neoplasia2023
37145169ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.Cancer Res2023
37398299H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas.bioRxiv2023
37195023ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.Cancer Res2023
36724689Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma.Neoplasia2023
36685825Liquid biopsy in pediatric brain tumors.Front Genet2023
34668975Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.Neuro Oncol2022
35464472Cell-Free Tumor DNA (cf-tDNA) Liquid Biopsy: Current Methods and Use in Brain Tumor Immunotherapy.Front Immunol2022
35840782Ultra-rapid somatic variant detection via real-time targeted amplicon sequencing.Commun Biol2022
35552452Characteristics of children ⿤36 months of age with DIPG: A report from the international DIPG registry.Neuro Oncol2022
35673129Expanding Access to CNS-TAP: Design, Development, and Initial Use of a Complex Precision Health Specialty Web App for Neuro-Oncology.Stud Health Technol Inform2022
36125896H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.J Clin Invest2022
35978801Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine.Front Oncol2022
36382108Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.Neurooncol Adv2022
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
34668975Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.Neuro Oncol2022
35157764Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.Neuro Oncol2022
35137228Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.Neuro Oncol2022
35323961Enhancing GD2 CAR T-cell therapy with IGF-1R blockade: Are DIPG CAR T cells ready for combinatorial therapy?Neuro Oncol2022
35840782Ultra-rapid somatic variant detection via real-time targeted amplicon sequencing.Commun Biol2022
35673129Expanding Access to CNS-TAP: Design, Development, and Initial Use of a Complex Precision Health Specialty Web App for Neuro-Oncology.Stud Health Technol Inform2022
35464472Cell-Free Tumor DNA (cf-tDNA) Liquid Biopsy: Current Methods and Use in Brain Tumor Immunotherapy.Front Immunol2022
35552452Characteristics of children ⿤36 months of age with DIPG: A report from the international DIPG registry.Neuro Oncol2022
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
36382108Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.Neurooncol Adv2022
36125896H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.J Clin Invest2022
35978801Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine.Front Oncol2022
35157764Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.Neuro Oncol2022
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Collaborators

Co-authored papers 23
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Co-authored papers 15
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University Children's Hospital Zurich
Co-authored papers 12
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USA University of Zurich
Co-authored papers 8
Co-authored papers 7
Children's Hospital of Philadelphia
Co-authored papers 6
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Co-authored papers 6
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University of California san francisco
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
Michigan Center for Translational Pathology, University of Michigan ann arbor
Co-authored papers 4
Co-authored papers 4
Perth Children's Hospital
Co-authored papers 4
Co-authored papers 4
Michigan Center for Translational Pathology.
Co-authored papers 4
Hasbro Children's Hospital, Brown University.
Co-authored papers 4
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Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
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