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Author Details

Chao-Ling Yang
Oregon Health & Science University
1991
51
32
PMIDPaper TitleJournal TitlePublished Year
37909221Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na<sup>+</sup> Channel (ENaC).Hypertension2024
35064051Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.J Am Soc Nephrol2022
35532068COP9 signalosome deletion promotes renal injury and distal convoluted tubule remodeling.Am J Physiol Renal Physiol2022
33719576Roles of WNK4 and SPAK in K<sup>+</sup>-mediated dephosphorylation of the NaCl cotransporter.Am J Physiol Renal Physiol2021
32789612Kidney Is Essential for Blood Pressure Modulation by Dietary Potassium.Curr Cardiol Rep2020
31908154Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin.Physiol Rep2020
31813255Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding.Am J Physiol Renal Physiol2020
31736353WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.Am J Physiol Renal Physiol2020
32715757Distal convoluted tubule Cl<sup>-</sup> concentration is modulated via K<sup>+</sup> channels and transporters.Am J Physiol Renal Physiol2020
30875275Salt-sensitive transcriptome of isolated kidney distal tubule cells.Physiol Genomics2019
31496133WNK4 limits distal calcium losses following acute furosemide treatment.Physiol Rep2019
29310825Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel.Kidney Int2018
29897280Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.Am J Physiol Renal Physiol2018
29921588C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity.J Biol Chem2018
30301860Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.J Am Soc Nephrol2018
29412704With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo.Am J Physiol Renal Physiol2018
28052988Potassium Sensing by Renal Distal Tubules Requires Kir4.1.J Am Soc Nephrol2017
26712527Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport.J Am Soc Nephrol2016
26432904Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension.J Am Soc Nephrol2016
26422504Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.Kidney Int2016
26607111Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.Biochem Biophys Res Commun2016
25565204Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride.Cell Metab2015
26552218[Protective effect of Danxuetong injection against testicular injury after testis torsion/detorsion in rats].Zhonghua Nan Ke Xue2015
26099046Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.Nat Med2015
24231659Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension.J Am Soc Nephrol2014
25250572Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.J Clin Invest2014
25113964WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.Hypertension2014
24799612Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension.Hypertension2014
22651238Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin.Clin Sci (Lond)2012
21896937Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension.Hypertension2011
21963515The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.Nat Med2011
21907141A SPAK isoform switch modulates renal salt transport and blood pressure.Cell Metab2011
19690383Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.J Clin Invest2009
18212265WNK kinases and renal sodium transport in health and disease: an integrated view.Hypertension2008
17194447WNK1 and WNK4 modulate CFTR activity.Biochem Biophys Res Commun2007
17975670The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.J Clin Invest2007
16204408Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform.Am J Physiol Renal Physiol2006
16709664WNK1 kinase isoform switch regulates renal potassium excretion.Proc Natl Acad Sci U S A2006
16820787WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron.Kidney Int2006
15841204Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport.J Clin Invest2005
15081430Comparison of WNK4 and WNK1 kinase and inhibiting activities.Biochem Biophys Res Commun2004
12671053WNK kinases regulate thiazide-sensitive Na-Cl cotransport.J Clin Invest2003
11457720Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule.Am J Physiol Renal Physiol2001
11208547Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes.Am J Physiol Gastrointest Liver Physiol2001
11459928Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells.Proc Natl Acad Sci U S A2001
10444585Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice.Am J Physiol1999
9335342Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice.Cell1997
7770640Renal cortical mitochondria are the source of oxygen free radicals enhanced by gentamicin.Ren Fail1995
7800247Mechanism of gentamicin nephrotoxicity in rats and the protective effect of zinc-induced metallothionein synthesis.Nephrol Dial Transplant1994
8184147Zinc-induced metallothionein synthesis could protect from gentamicin nephrotoxicity in suspended proximal tubules of rats.Ren Fail1994
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Collaborators

David H Ellison
Oregon Health and Science University
Co-authored papers 40
Kayla J Erspamer
Oregon Health & Science University
Co-authored papers 5
Jonathan W Nelson
Oregon Health and Science University
Co-authored papers 3
Elizabeth A Swanson
College of Nursing, The University of Iowa
Co-authored papers 2
Peter Libby
Co-authored papers 1
Cathleen Lutz
JAX Center for Precision Genetics
Co-authored papers 1
Yi Fu
Biofuels Institute, Jiangsu University
Co-authored papers 1
Larry L David
Oregon Health and Science University
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Richard P Lifton
The Rockefeller University
Co-authored papers 1
David M Cohen
Oregon Health and Science University
Co-authored papers 1
Xavier Jeunemaitre
Co-authored papers 1
Sophia Jeng
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Release 1.2