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Author Details

David J McConkey
Johns Hopkins School of Medicine
1986
340
95
PMIDPaper TitleJournal TitlePublished Year
37380560Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer.Eur Urol2024
37966367Association of Molecular Subtypes with Pathologic Response, PFS, and OS in a Phase II Study of COXEN with Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer.Clin Cancer Res2024
37775361Reply to Kentaro Inamura's Letter to the Editor re: Mingxiao Feng, Andres Matoso, Gabriel Epstein, et al. Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.05.023.Eur Urol2024
36754853Comparison of clinicopathological characteristics, gene expression profiles, mutational analysis, and clinical outcomes of pure and mixed small-cell carcinoma of the bladder.Histopathology2023
37596191Phase 2 Trial of Atezolizumab in Bacillus Calmette-Guérin-unresponsive High-risk Non-muscle-invasive Bladder Cancer: SWOG S1605.Eur Urol2023
37662238Combined Mek inhibition and <i>Pparg</i> activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis.bioRxiv2023
37087309Cell-free DNA Methylation as a Predictive Biomarker of Response to Neoadjuvant Chemotherapy for Patients with Muscle-invasive Bladder Cancer in SWOG S1314.Eur Urol Oncol2023
37414705Long-term Outcomes from a Phase 2 Study of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer (SWOG S1314; NCT02177695).Eur Urol2023
36820243Enfortumab Vedotin-related Cutaneous Toxicity and Radiographic Response in Patients with Urothelial Cancer: A Single-center Experience and Review of the Literature.Eur Urol Open Sci2023
36517188The Many Faces of Muscle-Invasive Bladder Cancer: Histopathological and Molecular Characterization.Semin Radiat Oncol2023
36717286A Phase 1 Trial of Durvalumab in Combination with Bacillus Calmette-Guerin (BCG) or External Beam Radiation Therapy in Patients with BCG-unresponsive Non-muscle-Invasive Bladder Cancer: The Hoosier Cancer Research Network GU16-243 ADAPT-BLADDER Study.Eur Urol2023
34801336Corrigendum to "Identification of Differential Tumor Subtypes of T1 Bladder Cancer" [Eur. Urol. 78 (2020) 533-537].Eur Urol2022
35847448Lentiviral interferon: A novel method for gene therapy in bladder cancer.Mol Ther Oncolytics2022
35699798Race reporting and disparities regarding clinical trials in bladder cancer: a systematic review.Cancer Causes Control2022
35811851Erratum: The origin of bladder cancer from mucosal field effects.iScience2022
35618577Characterizing molecular subtypes of high-risk non-muscle-invasive bladder cancer in African American patients.Urol Oncol2022
34933753Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non-muscle-invasive Bladder Cancer: Secondary Analysis of a Phase 3 Clinical Trial.Eur Urol2022
35169141Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer.Nat Commun2022
34736796A Molecular Inquiry into the Role of Antibody-Drug Conjugates in Bacillus Calmette-Guérin-exposed Non-muscle-invasive Bladder Cancer.Eur Urol2022
34731491BCG invokes superior STING-mediated innate immune response over radiotherapy in a carcinogen murine model of urothelial cancer.J Pathol2022
34426176Gender-specific Stratification of Survival Following Immune Checkpoint Inhibitor Therapy Based on Intratumoral Expression of a B cell Gene Signature.Eur Urol Oncol2022
31563523Circulating Tumor Cell and Circulating Tumor DNA Assays Reveal Complementary Information for Patients with Metastatic Urothelial Cancer.Eur Urol Oncol2021
33881933Expression Analysis of Same-Patient Metachronous and Synchronous Upper Tract and Bladder Urothelial Carcinoma.J Urol2021
33653802Rapamycin enhances BCG-specific γδ T cells during intravesical BCG therapy for non-muscle invasive bladder cancer: a randomized, double-blind study.J Immunother Cancer2021
33487562"Advancing bladder preservation: Biomarkers, decision-making, and therapy".Urol Oncol2021
33568346A Randomized Phase II Study of Coexpression Extrapolation (COXEN) with Neoadjuvant Chemotherapy for Bladder Cancer (SWOG S1314; NCT02177695).Clin Cancer Res2021
33901032Expression of Nectin-4 in Bladder Urothelial Carcinoma, in Morphologic Variants, and Nonurothelial Histotypes.Appl Immunohistochem Mol Morphol2021
33846523A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer.Br J Cancer2021
33500355Baseline Circulating Tumor Cell Count as a Prognostic Marker of PSA Response and Disease Progression in Metastatic Castrate-Sensitive Prostate Cancer (SWOG S1216).Clin Cancer Res2021
34607803γδ T Cells Support Antigen-Specific αβ T cell-Mediated Antitumor Responses during BCG Treatment for Bladder Cancer.Cancer Immunol Res2021
34514028Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer.Mol Ther Methods Clin Dev2021
34021032Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes.J Immunother Cancer2021
34131332100 years of Bacillus Calmette-Guérin immunotherapy: from cattle to COVID-19.Nat Rev Urol2021
34129819Molecular subtypes of upper tract urothelial cancer: Setting the stage for precision therapy.Cancer Cell2021
34148797New and topics: enfortumab vedotin mechanisms of response and resistance in urothelial cancer - What do we understand so far?Urol Oncol2021
33958145Molecular Biology of Bladder Cancer: Potential Implications for Therapy.Hematol Oncol Clin North Am2021
32061548Urothelial Cancers with Small Cell Variant Histology Have Confirmed High Tumor Mutational Burden, Frequent TP53 and RB Mutations, and a Unique Gene Expression Profile.Eur Urol Oncol2021
33358150Small Cell Bladder Cancer Response to Second-line and Beyond Checkpoint Inhibitor Therapy: Retrospective Experience.Clin Genitourin Cancer2021
32858539Urothelial Carcinoma In Situ of the Bladder: Correlation of CK20 Expression With Adaptive Immune Resistance, Response to BCG Therapy, and Clinical Outcome.Appl Immunohistochem Mol Morphol2021
32814637Clinical Restaging and Tumor Sequencing are Inaccurate Indicators of Response to Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer.Eur Urol2021
31411999Combined Next-generation Sequencing and Flow Cytometry Analysis for an Anti-PD-L1 Partial Responder over Time: An Exploration of Mechanisms of PD-L1 Activity and Resistance in Bladder Cancer.Eur Urol Oncol2021
31383572Does it matter whether a T1 high-grade tumor is molecularly classified?Eur Urol Oncol2021
31395481Does Variant Histology Change Management of Non-muscle-invasive Bladder Cancer?Eur Urol Oncol2021
32235944Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes.Nat Rev Urol2020
31712383Adaptive Immune Resistance to Intravesical BCG in Non-Muscle Invasive Bladder Cancer: Implications for Prospective BCG-Unresponsive Trials.Clin Cancer Res2020
32037144Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer: A Step in the Right Direction but Still a Long Way To Go. Eur Urol 2020;77:434-5.Eur Urol2020
33457262Update on bladder cancer molecular subtypes.Transl Androl Urol2020
32684305Identification of Differential Tumor Subtypes of T1 Bladder Cancer.Eur Urol2020
32842545Mutational Landscape and Environmental Effects in Bladder Cancer.Int J Mol Sci2020
32122956TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer.Mol Cancer Res2020
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Collaborators

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Yale School of Medicine
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CHRISTUS Santa Rosa Hospital-Medical Center
Co-authored papers 5
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 5
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Co-authored papers 5
Virginia Commonwealth University
Co-authored papers 5
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University of Colorado School of Medicine
Co-authored papers 4
Co-authored papers 4
France French Academy of Pharmacy
Co-authored papers 4
Federal University of Parana
Co-authored papers 4
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Baylor College of Medicine
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The University of Texas MD Anderson Cancer Center
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