Author details

Full Name

Vlado Dan????k

Affiliation

Broad Institute

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36125173	Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science.	Clin Transl Sci	2022
35611543	Progress toward a universal biomedical data translator.	Clin Transl Sci	2022
35439415	Phenotypic Screening for Small Molecules that Protect Î²-Cells from Glucolipotoxicity.	ACS Chem Biol	2022
36396978	A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.	Nat Cell Biol	2022
34130532	The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes.	SLAS Discov	2021
33755673	Knowledge Beacons: Web services for data harvesting of distributed biomedical knowledge.	PLoS One	2021
32939090	Plasticity of ether lipids promotes ferroptosis susceptibility and evasion.	Nature	2020
30962421	A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.	Nat Commun	2019
31266947	Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases.	Nat Commun	2019
31028261	High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases.	Nat Commun	2019
31051099	A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9.	Cell	2019
29073062	Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.	Proc Natl Acad Sci U S A	2017
28327978	A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.	Gigascience	2017
29220450	CTD2 Dashboard: a searchable web interface to connect validated results from the Cancer Target Discovery and Development Network.	Database (Oxford)	2017
26953159	Inhibition of DYRK1A Stimulates Human Î²-Cell Proliferation.	Diabetes	2016
26656090	Correlating chemical sensitivity and basal gene expression reveals mechanism of action.	Nat Chem Biol	2016
27751627	A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.	Trends Microbiol	2016
27012813	DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.	Clin Cancer Res	2016
25565210	High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function.	Cell Metab	2015
26482930	Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.	Cancer Discov	2015
26042473	Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.	J Am Chem Soc	2015
26195741	Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.	Proc Natl Acad Sci U S A	2015
25660025	Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.	Cell Rep	2015
24464433	Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses.	J Biomol Screen	2014
25024206	Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.	Proc Natl Acad Sci U S A	2014
25114223	Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.	Proc Natl Acad Sci U S A	2014
24759943	Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming.	PLoS One	2014
24710340	Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles.	J Biomol Screen	2014
23508189	Target identification and mechanism of action in chemical biology and drug discovery.	Nat Chem Biol	2013
24161946	Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.	Nat Chem Biol	2013
23993102	An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.	Cell	2013
23696745	Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.	PLoS Genet	2013
22863010	Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.	Cell	2012
21482810	Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections.	Proc Natl Acad Sci U S A	2011
20565092	Distinct biological network properties between the targets of natural products and disease genes.	J Am Chem Soc	2010
20696901	Small-molecule inducers of insulin expression in pancreatic alpha-cells.	Proc Natl Acad Sci U S A	2010
16372355	Edge-count probabilities for the identification of local protein communities and their organization.	Proteins	2006
15767772	Analyzing protein lists with large networks: edge-count probabilities in random graphs with given expected degrees.	J Comput Biol	2005
15468760	Detection of activity centers in cellular pathways using transcript profiling.	J Biopharm Stat	2004
11157792	Efficiency of database search for identification of mutated and modified proteins via mass spectrometry.	Genome Res	2001
11382361	Mutation-tolerant protein identification by mass spectrometry.	J Comput Biol	2000
10582570	De novo peptide sequencing via tandem mass spectrometry.	J Comput Biol	1999
9773346	Estimation for restriction sites observed by optical mapping using reversible-jump Markov Chain Monte Carlo.	J Comput Biol	1998
9228611	Hardness of flip-cut problems from optical mapping.	J Comput Biol	1997
9278060	Local rules for protein folding on a triangular lattice and generalized hydrophobicity in the HP model.	J Comput Biol	1997

1 - 45 of 45

Wail Ba-Alawi

Princess Margaret Cancer Centre, University Health Network, University Ave.

Career Start Year 2013

Number of shared co-authors 0

Peter Cimermancic

Verily Life Sciences LLC

Career Start Year 2011

Number of shared co-authors 0

Woochang Hwang

College of Medicine, Hanyang University

Career Start Year 2006

Number of shared co-authors 0

Avi Ma'ayan

Icahn School of Medicine at Mount Sinai

Career Start Year 2005

Number of shared co-authors 6

Michael Hsing

University of British Columbia

Career Start Year 2004

Number of shared co-authors 0

Tanusya M Murali

Yong Loo Lin School of Medicine, National University of Singapore

Career Start Year 2003

Number of shared co-authors 1

Jake Y. Chen (CM4AI)

University of Alabama at Birmingham

Career Start Year 2003

Number of shared co-authors 0

Andrey Sivachenko

Cystic Fibrosis Foundation

Career Start Year 2003

Number of shared co-authors 9

Gerald H Lushington

Inc. 16 Dekalb Pike

Career Start Year 2002

Number of shared co-authors 0

Gary D Bader

University of Toronto

Career Start Year 2000

Number of shared co-authors 8

Tero Aittokallio

Institute for Molecular Medicine Finland (FIMM), University of Helsinki

Career Start Year 1999

Number of shared co-authors 6

Frederick P Roth

University of Toronto

Career Start Year 1998

Number of shared co-authors 6

Igor Jurisica

Schroeder Arthritis Institute

Career Start Year 1998

Number of shared co-authors 1

Stephan C Sch??rer

Institute for Data Science and Computing, University of Miami

Career Start Year 1998

Number of shared co-authors 9

Lars Juhl Jensen

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Career Start Year 1998

Number of shared co-authors 1

Benno Schwikowski

Center for Bioinformatics, Institut Pasteur CNRS

Career Start Year 1997

Number of shared co-authors 3

Patrick Aloy

Institucio Catalana de Recerca i Estudis Avancats (ICREA)

Career Start Year 1997

Number of shared co-authors 1

Yingyao Zhou

Genomics Institute of the Novartis Research Foundation

Career Start Year 1997

Number of shared co-authors 5

Bissan Al-Lazikani

The University of Texas MD Anderson Cancer Center

Career Start Year 1997

Number of shared co-authors 2

Trey Ideker (CM4AI)

University of California San Diego

Career Start Year 1996

Number of shared co-authors 9

Niklas Blomberg

Universitat Tubingen, Institut fur Arbeitsmedizin

Career Start Year 1996

Number of shared co-authors 3

Ioannis Xenarios

University of Lausanne

Career Start Year 1994

Number of shared co-authors 4

Hiroshi Mamitsuka

Institute for Chemical Research, Kyoto University

Career Start Year 1994

Number of shared co-authors 2

Bonnie Berger

Massachusetts Institute of Technology

Career Start Year 1994

Number of shared co-authors 4

Edward M Marcotte

University of Texas

Career Start Year 1993

Number of shared co-authors 1

Jason E McDermott

Pacific Northwest National Laboratory

Career Start Year 1993

Number of shared co-authors 1

Joel S Bader

Johns Hopkins University

Career Start Year 1993

Number of shared co-authors 3

Ram Samudrala

Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Career Start Year 1990

Number of shared co-authors 0

David Feny??

Institute for Systems Genetics, NYU Grossman School of Medicine

Career Start Year 1989

Number of shared co-authors 1

Russ B Altman

Stanford University

Career Start Year 1982

Number of shared co-authors 6

row(s) 1 - 30 of 30

Paul A Clemons

Broad Institute

Co-authored papers 31

Stuart L Schreiber

Broad Institute

Co-authored papers 22

Bridget K Wagner

Co-authored papers 15

Alykhan F Shamji

Center for the Science of Therapeutics, Broad Institute

Co-authored papers 14

Joshua A Bittker

Co-authored papers 9

Amit Choudhary

Broad Institute of MIT and Harvard

Co-authored papers 5

Todd R Golub

Broad Institute of MIT and Harvard

Co-authored papers 4

Anne E Carpenter

Broad Institute of MIT and Harvard

Co-authored papers 4

Mark-Anthony Bray

Co-authored papers 3

Matthew G Rees

Co-authored papers 3

Joel Pradines

Momenta Pharmaceuticals Inc

Co-authored papers 3

Jaime H Cheah

Johns Hopkins University School of Medicine

Co-authored papers 3

Ted Liefeld

Moores Cancer Center, University of California San Diego

Co-authored papers 3

Stefan Kubicek

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

Co-authored papers 3

Clary B Clish

Broad Institute of MIT and Harvard

Co-authored papers 3

David R Liu

Co-authored papers 3

Ramnik J Xavier

Broad Institute of MIT and Harvard

Co-authored papers 3

Steven A Carr

Broad Institute of MIT and Harvard

Co-authored papers 3

Pavel A Pevzner

University of California

Co-authored papers 3

Richard Bruskiewich

Delphinai Corporation

Co-authored papers 2

Chris Bizon

Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill

Co-authored papers 2

Michel Dumontier

Institute of Data Science, Maastricht University

Co-authored papers 2

James E Bradner

Co-authored papers 2

Maria Kost-Alimova

Co-authored papers 2

Benjamin Alexander

Co-authored papers 2

Nomi L Harris

Lawrence Berkely National Laboratory, Massachusetts Institute of Technology, Princeton University

Co-authored papers 2

Subbaratnam Muthukrishnan

Kansas State University

Co-authored papers 2

Karamarie Fecho

Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill

Co-authored papers 2

Chris Sander

Broad Institute of MIT and Harvard

Co-authored papers 2

Gustavo Glusman

Institute for Systems Biology

Co-authored papers 2

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators