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Author Details
Full Name
Roderic G Eckenhoff
Affiliation
University of Pennsylvania, Perelman School of Medicine
ORCID
Career Start Year
1984
Papers
225
H Index
47
Expertise
CM4AI Collaborator
Sarah J Ratcliffe (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36799408
Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network.
Alzheimers Dement
2023
37436580
A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients.
Neurotherapeutics
2023
36849414
<i>In Vivo</i> Photoadduction of Anesthetic Ligands in Mouse Brain Markedly Extends Sedation and Hypnosis.
J Neurosci
2023
33214467
Alzheimer's Dementia After Exposure to Anesthesia and Surgery in the Elderly: A Matched Natural Experiment Using Appendicitis.
Ann Surg
2022
35899460
Propofol directly binds to and inhibits TLR7.
FASEB J
2022
35101245
Risk of Parkinson's disease after anaesthesia and surgery.
Br J Anaesth
2022
33413977
Improving perioperative brain health: an expert consensus review of key actions for the perioperative care team.
Br J Anaesth
2021
33905229
Ketamine Metabolite (2<i>R</i>,6<i>R</i>)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors.
ACS Chem Neurosci
2021
34673725
Anesthetic Effects on the Progression of Parkinson Disease in the Rat DJ-1 Model.
Anesth Analg
2021
34607428
Binding Sites and the Mechanism of Action of Propofol and a Photoreactive Analogue in Prokaryotic Voltage-Gated Sodium Channels.
ACS Chem Neurosci
2021
34260401
Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4-S5 linker in activation and slow inactivation.
Proc Natl Acad Sci U S A
2021
33025584
Association Between Exposure to General Versus Regional Anesthesia and Risk of Dementia in Older Adults.
J Am Geriatr Soc
2021
33355437
Synthesis and Characterization of a Diazirine-Based Photolabel of the Nonanesthetic Fropofol.
ACS Chem Neurosci
2021
31424496
Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy.
Cardiovasc Res
2020
31834869
Perioperative Neurocognitive Disorder: State of the Preclinical Science.
Anesthesiology
2020
33345771
Mechanistic insights into volatile anesthetic modulation of K2P channels.
Elife
2020
33090695
Using Medicare claims in identifying Alzheimer's disease and related dementias.
Alzheimers Dement
2020
32804873
The future of research in anesthesiology.
Int Anesthesiol Clin
2020
32690248
Untangling anaesthesia and amyloid.
Br J Anaesth
2020
32901993
The effect of anesthetics on toll like receptor 9.
FASEB J
2020
32978423
A vertebrate model to reveal neural substrates underlying the transitions between conscious and unconscious states.
Sci Rep
2020
32212231
International drive to illuminate delirium: A developing public health blueprint for action.
Alzheimers Dement
2020
32171526
The role of propofol hydroxyl group in 5-lipoxygenase recognition.
Biochem Biophys Res Commun
2020
32536445
Human plasma biomarker responses to inhalational general anaesthesia without surgery.
Br J Anaesth
2020
32452866
Perioperative Neurocognitive Disorder: Reply.
Anesthesiology
2020
31147199
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
Trends Pharmacol Sci
2019
31675483
Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.
FASEB J
2019
31638765
Azi-medetomidine: Synthesis and Characterization of a Novel α2 Adrenergic Photoaffinity Ligand.
ACS Chem Neurosci
2019
31210651
Prevalence and Multivariable Factors Associated With Preoperative Cognitive Impairment in Outpatient Surgery in the United States.
Anesth Analg
2019
31313736
Nomenclature for Perioperative Cognitive Disorders: Reply.
Anesthesiology
2019
31425253
In Response.
Anesth Analg
2019
31422800
Recommendations for a new perioperative cognitive impairment nomenclature.
Alzheimers Dement
2019
30898682
Sex effects on behavioral markers of emergence from propofol and isoflurane anesthesia in rats.
Behav Brain Res
2019
31071106
Volatile anesthetics affect macrophage phagocytosis.
PLoS One
2019
30768926
Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency.
Biochem Pharmacol
2019
29452796
One to rule them all?
Br J Anaesth
2018
29965816
Gone Fishing⿦.
Anesthesiology
2018
30018039
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.
J Gen Physiol
2018
30018038
Propofol inhibits prokaryotic voltage-gated Na<sup>+</sup> channels by promoting activation-coupled inactivation.
J Gen Physiol
2018
29844014
An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules.
J Biol Chem
2018
30325016
Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.
Acta Anaesthesiol Scand
2018
30324338
Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.
Can J Anaesth
2018
30347621
Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-20181.
J Alzheimers Dis
2018
30336844
Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.
Br J Anaesth
2018
30303868
Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group.
Anesth Analg
2018
30325806
Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-2018.
Anesthesiology
2018
30325748
Recommendations for the Nomenclature of Cognitive Change Associated With Anaesthesia and Surgery-2018.
Anesth Analg
2018
28204960
Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels.
Mol Neurobiol
2018
29588044
Preface.
Methods Enzymol
2018
29588031
Identification of General Anesthetic Target Protein-Binding Sites by Photoaffinity Labeling and Mass Spectrometry.
Methods Enzymol
2018
1 - 50 of 225
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row(s) 1 - 30 of 30
Collaborators
Maryellen F Eckenhoff
University of Pennsylvania, Perelman School of Medicine.
Co-authored papers
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Duke University Medical Center
Co-authored papers
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Pei Tang
Sichuan University
Co-authored papers
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Benjamin A Garcia
University of Pennsylvania
Co-authored papers
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Nanjing Drum Tower Hospital
Co-authored papers
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Mayo Clinic Rochester
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Duke University Medical Center
Co-authored papers
5
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University of Pennsylvania
Co-authored papers
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Co-authored papers
3
Sarah J Ratcliffe (CM4AI)
University of Virginia
Co-authored papers
2
Anton Simeonov
Co-authored papers
2
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University of Pennsylvania
Co-authored papers
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Catherine C Price
University of Florida College of Medicine.
Co-authored papers
2
John A Detre
Center for Functional Neuroimaging, University of Pennsylvania
Co-authored papers
2
James M Clark
Institute for Environmental Medicine, University of Pennsylvania School of Medicine
Co-authored papers
2
Jeffery G Saven
University of Pennsylvania
Co-authored papers
2
Joseph P Mathew
Duke University School of Medicine
Co-authored papers
2
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Co-authored papers
2
Robert Gelfand
Institute for Environmental Medicine, University of Pennsylvania School of Medicine
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2
Thomas F Floyd
The University of Texas Southwestern
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2
John W Devlin
Brigham and Women's Hospital
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