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Author Details

Dipanjan Chowdhury
Dana-Farber Cancer Institute
1999
99
51
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36202931Targeting replication stress in cancer therapy.Nat Rev Drug Discov2023
36202931Targeting replication stress in cancer therapy.Nat Rev Drug Discov2023
37696958Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.Nat Struct Mol Biol2023
37773750Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction.Cell Rep2023
37773238An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.Nat Commun2023
37034578Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs.bioRxiv2023
37131705An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.bioRxiv2023
37301262Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study.Radiother Oncol2023
37291133Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles.Nat Commun2023
37696958Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.Nat Struct Mol Biol2023
37773750Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction.Cell Rep2023
37773238An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.Nat Commun2023
37291133Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles.Nat Commun2023
37301262Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study.Radiother Oncol2023
37131705An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.bioRxiv2023
37034578Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs.bioRxiv2023
34887522Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours.Br J Cancer2022
35530324A Translational Model to Improve Early Detection of Epithelial Ovarian Cancers.Front Oncol2022
35868254TOPBPing up DSBs with PARylation.Mol Cell2022
35484586Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.Genome Biol2022
36442094CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining.Proc Natl Acad Sci U S A2022
34887522Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours.Br J Cancer2022
35530324A Translational Model to Improve Early Detection of Epithelial Ovarian Cancers.Front Oncol2022
35484586Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.Genome Biol2022
36442094CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining.Proc Natl Acad Sci U S A2022
35868254TOPBPing up DSBs with PARylation.Mol Cell2022
34354234ASTE1 cutting to block DNA end resection.Nat Cell Biol2021
33961797TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.Mol Cell2021
33952190Correction to: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.BMC Genomics2021
34354234ASTE1 cutting to block DNA end resection.Nat Cell Biol2021
34552099A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer.Nat Commun2021
34607711MicroRNA profiling in a case-control study of African American women with uterine serous carcinoma.Gynecol Oncol2021
34552099A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer.Nat Commun2021
34607711MicroRNA profiling in a case-control study of African American women with uterine serous carcinoma.Gynecol Oncol2021
33961797TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.Mol Cell2021
33952190Correction to: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.BMC Genomics2021
32424117Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.Nat Commun2020
32424117Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.Nat Commun2020
32193378Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.Nat Commun2020
32005151A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs.BMC Genomics2020
32404420Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome.Proc Natl Acad Sci U S A2020
31655196Circulating microRNAs as Biomarkers of Radiation Exposure: A Systematic Review and Meta-Analysis.Int J Radiat Oncol Biol Phys2020
31915374TRIP13 regulates DNA repair pathway choice through REV7 conformational change.Nat Cell Biol2020
33108758CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress.Mol Cell2020
32556091Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer.Carcinogenesis2020
32553118Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial.Lancet Oncol2020
31915374TRIP13 regulates DNA repair pathway choice through REV7 conformational change.Nat Cell Biol2020
31655196Circulating microRNAs as Biomarkers of Radiation Exposure: A Systematic Review and Meta-Analysis.Int J Radiat Oncol Biol Phys2020
32005151A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs.BMC Genomics2020
33108758CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress.Mol Cell2020
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Collaborators

Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 17
Wojciech Fendler
Co-authored papers 17
Judy Lieberman
Boston Children's Hospital
Co-authored papers 14
Huy Nguyen
The University of Danang-University of Science and Technology
Co-authored papers 5
David Kozono
Co-authored papers 4
David M Weinstock
Merck & Co.
Co-authored papers 3
Myriam Gorospe
National Institute on Aging (NIA), National Institutes of Health (NIH)
Co-authored papers 3
Norbert H??bner
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 2
Claudia Lukas
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 2
Michael-Christopher Keogh
EpiCypher Inc.
Co-authored papers 2
Elena Ivanova
Dana-Farber Cancer Institute
Co-authored papers 2
Stephen Buratowski
Harvard Medical School
Co-authored papers 2
Peter K Sorger
Co-authored papers 2
Lorelei A Mucci
Co-authored papers 2
Clark C Chen
University of Minnesota
Co-authored papers 2
Subhajyoti De
Co-authored papers 2
Sandro Santagata
Co-authored papers 2
Jie Bian
Co-authored papers 2
Massimo Loda
Weill Medical College of Cornell University
Co-authored papers 2
Meir J Stampfer
Brigham and Women's Hospital
Co-authored papers 2
Peter J Park
Harvard Medical School
Co-authored papers 2
Judy E Garber
Dana-Farber Cancer Institute
Co-authored papers 2
Kotb Abdelmohsen
National Institute on Aging, National Institutes of Health
Co-authored papers 2
John A Tainer
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Daphne A Haas-Kogan
Co-authored papers 2
Clarence Yapp
Co-authored papers 2
Cyril H Benes
Co-authored papers 2
Deborah Palliser
Albert Einstein College of Medicine
Co-authored papers 2
Nikhil Kumar
Co-authored papers 2
Sven Bilke
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Release 1.2