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Author Details

Cleber A Trujillo
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
2006
49
23
PMIDPaper TitleJournal TitlePublished Year
36385168Impact of alcohol exposure on neural development and network formation in human cortical organoids.Mol Psychiatry2023
36202289Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids.Neurobiol Dis2022
33077405RNA processing in neurological tissue: development, aging and disease.Semin Cell Dev Biol2021
33574182Reintroduction of the archaic variant of <i>NOVA1</i> in cortical organoids alters neurodevelopment.Science2021
33727673Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.Mol Psychiatry2021
33501759Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.EMBO Mol Med2021
33888873Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy.Mol Psychiatry2021
34648331Response to Comment on "Reintroduction of the archaic variant of <i>NOVA1</i> in cortical organoids alters neurodevelopment".Science2021
34433918Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.Mol Psychiatry2021
34548630Correction: Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.Mol Psychiatry2021
34122014All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors.Front Cell Neurosci2021
34010654MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling.Cell Rep2021
33328864Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids.Front Neurosci2020
31956038Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin α<sub>v</sub>β<sub>5</sub> Axis.Cell Stem Cell2020
33363173Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids.Front Cell Dev Biol2020
31474560Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development.Cell Stem Cell2019
28576415Stem cell contributions to neurological disease modeling and personalized medicine.Prog Neuropsychopharmacol Biol Psychiatry2018
30142987Direct Generation of Human Cortical Organoids from Primary Cells.Stem Cells Dev2018
30377071Brain Organoids and the Study of Neurodevelopment.Trends Mol Med2018
27378147Altered proliferation and networks in neural cells derived from idiopathic autistic individuals.Mol Psychiatry2017
28291261Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons.Transl Psychiatry2017
28803918Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.Cell Stem Cell2017
26944080Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction.Proc Natl Acad Sci U S A2016
26347316Altered neuronal network and rescue in a human MECP2 duplication model.Mol Psychiatry2016
27528403Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation.J Cell Sci2016
27509850A human neurodevelopmental model for Williams syndrome.Nature2016
26755826Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony.Hum Mol Genet2016
25758980Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation.Neurochem Res2015
26554899Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells.Elife2015
26233465Effects of ATP and NGF on Proliferation and Migration of Neural Precursor Cells.Neurochem Res2015
25839228Roles of kinins in the nervous system.Cell Transplant2015
23036599Stem cells and modeling of autism spectrum disorders.Exp Neurol2014
23894286Rescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.PLoS One2013
22415841Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.Curr Protoc Stem Cell Biol2012
23132855Kinin-B2 receptor activity determines the differentiation fate of neural stem cells.J Biol Chem2012
22730318Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells.J Biol Chem2012
20617399Directed differentiation of neural progenitors into neurons is accompanied by altered expression of P2X purinergic receptors.J Mol Neurosci2011
21674001Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation.PLoS One2011
20461497Alpha 7 nicotinic acetylcholine receptor expression and activity during neuronal differentiation of PC12 pheochromocytoma cells.J Mol Neurosci2010
18988295Novel perspectives of neural stem cell differentiation: from neurotransmitters to therapeutics.Cytometry A2009
19614740Interaction with calmodulin is important for the secretion of thimet oligopeptidase following stimulation.FEBS J2009
17868151Mode of cembranoid action on embryonic muscle acetylcholine receptor.J Neurosci Res2008
18598727A novel physiological property of snake bradykinin-potentiating peptides-reversion of MK-801 inhibition of nicotinic acetylcholine receptors.Peptides2008
18302192Kinin-B2 receptor expression and activity during differentiation of embryonic rat neurospheres.Cytometry A2008
17481842Immobilized P2X2 purinergic receptor stationary phase for chromatographic determination of pharmacological properties and drug screening.J Pharm Biomed Anal2007
19668516Development of the anti-VEGF aptamer to a therapeutic agent for clinical ophthalmology.Clin Ophthalmol2007
18404445New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders.Purinergic Signal2007
16388598Inhibition mechanism of the recombinant rat P2X(2) receptor in glial cells by suramin and TNP-ATP.Biochemistry2006
17017882DNA and RNA aptamers: from tools for basic research towards therapeutic applications.Comb Chem High Throughput Screen2006
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Collaborators

Alysson R Muotri
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 28
Priscilla D Negraes
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 24
Gabriel G Haddad
university of california san diego
Co-authored papers 4
Wei Wu
University of California
Co-authored papers 4
John R Yates
TheScripps Research Institute
Co-authored papers 4
Jonathan Sebat
University of California San Diego
Co-authored papers 3
Matthieu Vandenberghe
Oslo University Hospital
Co-authored papers 2
Anna Devor
Boston University
Co-authored papers 2
Gene W Yeo
University of California
Co-authored papers 2
Sebastian Preissl
Center for Epigenomics, University of California San Diego
Co-authored papers 2
Anders M Dale
University of California San Diego
Co-authored papers 2
Justin Buchanan
Center for Epigenomics & Department of Cellular & Molecular Medicine.
Co-authored papers 2
Isaac A Chaim
University of California San Diego
Co-authored papers 2
Allen Wang
Center for Epigenomics, University of California San Diego School of Medicine
Co-authored papers 2
Terry Gaasterland
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 1
Jacob Ellegood
Hospital for Sick Children
Co-authored papers 1
Ole A Andreassen
Oslo University Hospital & Institute of Clinical Medicine, University of Oslo
Co-authored papers 1
Eric Courchesne
University of California
Co-authored papers 1
Xiang-Dong Fu
Co-authored papers 1
Beth Shapiro
Co-authored papers 1
Robert J Wechsler-Reya
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Timothy T Brown
University of California San Diego
Co-authored papers 1
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
Co-authored papers 1
Daniel B McClatchy
Co-authored papers 1
Briana C Prager
Massachusetts General Hospital
Co-authored papers 1
Emily C Wheeler
University of California
Co-authored papers 1
Daniel H Geschwind
University of California los angeles
Co-authored papers 1
Richard E Green
Co-authored papers 1
Cynthia Carter Barnes
University of California San Diego
Co-authored papers 1
Srdjan Djurovic
Oslo University Hospital
Co-authored papers 1
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