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Author Details

Jon Clardy
Harvard Medical School, Blavatnik Institute
1973
380
87
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36758518Gut microbiome lipid metabolism and its impact on host physiology.Cell Host Microbe2023
36952265<i>Collinsella aerofaciens</i> Produces a pH-Responsive Lipid Immunogen.J Am Chem Soc2023
37163788Discovering functional small molecules in the gut microbiome.Curr Opin Chem Biol2023
35049898Bacillimidazoles A-F, Imidazolium-Containing Compounds Isolated from a Marine <i>Bacillus</i>.Mar Drugs2022
36452178Identification of a growth factor required for culturing specific fastidious oral bacteria.J Oral Microbiol2022
35896748Akkermansia muciniphila phospholipid induces homeostatic immune responses.Nature2022
35129341Lyme Disease, <i>Borrelia burgdorferi</i>, and Lipid Immunogens.J Am Chem Soc2022
33350306Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in <i>Clostridium perfringens</i>.ACS Chem Biol2021
33655067Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis.ACS Cent Sci2021
33620482Bacterial diketopiperazines stimulate diatom growth and lipid accumulation.Plant Physiol2021
33591189Chemical Exchanges between Multilateral Symbionts.Org Lett2021
34734219Benefiting from big data in natural products: importance of preserving foundational skills and prioritizing data quality.Nat Prod Rep2021
34417172Neuronal control of maternal provisioning in response to social cues.Sci Adv2021
34042443A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters.J Chem Inf Model2021
33962985<i>Burkholderia</i> from Fungus Gardens of Fungus-Growing Ants Produces Antifungals That Inhibit the Specialized Parasite <i>Escovopsis</i>.Appl Environ Microbiol2021
33972416Capsular polysaccharide correlates with immune response to the human gut microbe <i>Ruminococcus gnavus</i>.Proc Natl Acad Sci U S A2021
33352109Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways.Cell Host Microbe2021
32315170Parsing Molecules for Drug Discovery.Biochemistry2020
31896661Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A.Science2020
33101237Cycloheximide-Producing <i>Streptomyces</i> Associated With <i>Xyleborinus saxesenii</i> and <i>Xyleborus affinis</i> Fungus-Farming Ambrosia Beetles.Front Microbiol2020
32738587A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E.Int J Parasitol Drugs Drug Resist2020
32453775A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity.PLoS Pathog2020
30531975GABA-modulating bacteria of the human gut microbiota.Nat Microbiol2019
31839835Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering.Beilstein J Org Chem2019
31831655Molecular messages in human microbiota.Science2019
31182571<i>Ruminococcus gnavus</i>, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide.Proc Natl Acad Sci U S A2019
31232690An elusive electron shuttle from a facultative anaerobe.Elife2019
31600443Pyonitrins A-D: Chimeric Natural Products Produced by <i>Pseudomonas protegens</i>.J Am Chem Soc2019
31344052Microbial community modulates growth of symbiotic fungus required for stingless bee metamorphosis.PLoS One2019
30833338Metabolites Involved in Immune Evasion by <i>Batrachochytrium dendrobatidis</i> Include the Polyamine Spermidine.Infect Immun2019
28745342Defense contracts: molecular protection in insect-microbe symbioses.Chem Soc Rev2018
30190434A plant-responsive bacterial-signaling system senses an ethanolamine derivative.Proc Natl Acad Sci U S A2018
29931794Mammalian Cells Engineered To Produce New Steroids.Chembiochem2018
30228116Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen.Proc Natl Acad Sci U S A2018
29844859Oridonin inhibits aberrant AKT activation in breast cancer.Oncotarget2018
30576339A high-throughput, whole cell assay to identify compounds active against carbapenem-resistant Klebsiella pneumoniae.PLoS One2018
30648156Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.ACS Cent Sci2018
30282739Convergent evolution of complex structures for ant-bacterial defensive symbiosis in fungus-farming ants.Proc Natl Acad Sci U S A2018
30559356Tiny crystals have big potential for determining structures of small molecules.Nature2018
29700993Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.Chembiochem2018
29361220Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism.J Am Chem Soc2018
29416082Pyrazines from bacteria and ants: convergent chemistry within an ecological niche.Sci Rep2018
29678921A Repeating Sulfated Galactan Motif Resuscitates Dormant Micrococcus luteus Bacteria.Appl Environ Microbiol2018
29348592Stingless Bee Larvae Require Fungal Steroid to Pupate.Sci Rep2018
28893599Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata.Bioorg Med Chem2017
28111075Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.Cell2017
28385960Unequivocal determination of complex molecular structures using anisotropic NMR measurements.Science2017
28326787Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides.Org Lett2017
28207275Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39.Org Lett2017
29503481Absolute Configurations of Griseorhodins A and C.Tetrahedron Lett2017
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Collaborators

University of Wisconsin - Madison
Co-authored papers 31
Stanford University
Co-authored papers 14
The Broad Institute
Co-authored papers 13
Co-authored papers 10
Broad Institute
Co-authored papers 7
Broad Institute of MIT and Harvard
Co-authored papers 7
Indiana University
Co-authored papers 5
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Co-authored papers 5
The Joint Center for Structural Genomics, Stanford University
Co-authored papers 4
Co-authored papers 3
Wageningen University
Co-authored papers 3
Smithsonian Tropical Research Institute
Co-authored papers 3
Harvard Medical School
Co-authored papers 3
The Manton Center for Orphan Disease Research, Boston Children's Hospital
Co-authored papers 2
Co-authored papers 2
Verily Life Sciences LLC
Co-authored papers 2
Co-authored papers 2
Department of Energy (DOE) Joint Genome Institute
Co-authored papers 2
Co-authored papers 2
Simon Fraser University
Co-authored papers 2
Scripps Research Institute
Co-authored papers 2
Vertex Pharmaceuticals
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Whitehead Institute for Biomedical Research
Co-authored papers 2
Lerner Research Institute of the Cleveland Clinic
Co-authored papers 2
Harvard T.H. Chan School of Public Health
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 2
Manchester Institute of Biotechnology, University of Manchester
Co-authored papers 2