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Author Details

Robert Siddaway
Hospital for Sick Children
2011
24
15
PMIDPaper TitleJournal TitlePublished Year
37771132The Incidence of Multiple Fusions in a Series of Pediatric Soft Tissue and Bone Tumors.Pediatr Dev Pathol2024
35605606Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.Neuro Oncol2023
37748705Clinical Implementation of MetaFusion for Accurate Cancer-Driving Fusion Detection from RNA Sequencing.J Mol Diagn2023
35102191Splicing is an alternate oncogenic pathway activation mechanism in glioma.Nat Commun2022
36070144Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma.Acta Neuropathol2022
36089195The in vivo Interaction Landscape of Histones H3.1 and H3.3.Mol Cell Proteomics2022
33355208DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.Cancer Discov2021
33563663Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition.Cancer Discov2021
33944895MetaFusion: a high-confidence metacaller for filtering and prioritizing RNA-seq gene fusion candidates.Bioinformatics2021
31398252Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas.Neuro Oncol2020
31907541Modeling DIPG in the mouse brainstem.Neuro Oncol2020
33277484Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.Nat Commun2020
32938641Cancers from Novel <i>Pole</i>-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade.Cancer Res2020
32142668Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.Cancer Cell2020
32289278Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas.Cancer Cell2020
32531202Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.Mol Cell2020
31207090MITF controls the TCA cycle to modulate the melanoma hypoxia response.Pigment Cell Melanoma Res2019
28096186Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.Genes Dev2017
27577993Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma.Acta Neuropathol Commun2016
25803486Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.Elife2015
26351319Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma.Mol Cancer Ther2015
26530832MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Nat Commun2015
26092939Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.J Cell Sci2015
21807880PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks.J Cell Biol2011
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Collaborators

Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 14
Sanja Pajovic
Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Co-authored papers 6
Uri Tabori
Co-authored papers 5
Eric Bouffet
The Hospital for Sick Children
Co-authored papers 5
Colin R Goding
Ludwig Institute for Cancer Research, University of Oxford
Co-authored papers 5
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 4
Annie Huang
Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
Co-authored papers 3
Michael Brudno
University of Toronto
Co-authored papers 3
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 2
Francesca M Buffa
University of Oxford
Co-authored papers 2
David Malkin
Hospital for Sick Children
Co-authored papers 2
David S Ziegler
Co-authored papers 2
Eir??kur Steingr??msson
BioMedical Center, University of Iceland
Co-authored papers 2
Lea F Surrey
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Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
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Sameer Agnihotri
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Thomas Strub
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James T Rutka
Hospital for Sick Children
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Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Arnar Palsson
Institute of Life and Environmental Sciences, University of Iceland
Co-authored papers 1
Margret H Ogmundsdottir
Biomedical Center, University of Iceland
Co-authored papers 1
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 1
Daniel C Bowers
University of Texas Southwestern Medical School
Co-authored papers 1
Xuhong Cao
Michigan Center for Translational Pathology.
Co-authored papers 1
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 1
Kristina A Cole
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Eric Van Otterloo
College of Dentistry & Dental Clinics, University of Iowa
Co-authored papers 1
Matthew D Dun
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Robert A Cornell
University of Iowa
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Maura Massimino
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