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Author Details

Tarek Abbas
University of Virginia
2001
39
26
PMIDPaper TitleJournal TitlePublished Year
36538614A Step Toward Personalized Surgical Decision Making: Machine Learning Predicts 1 Versus Numerous Melanoma Lymph Node Metastases Using RNA-sequencing.Ann Surg2023
37077937Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells.Cancer Res Commun2023
32606249The Role of Ubiquitination and SUMOylation in DNA Replication.Curr Issues Mol Biol2021
34707113A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.Nat Commun2021
34718766MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage.Nucleic Acids Res2021
33976187Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly.Nat Commun2021
33068408A robust CRISPR-Cas9-based fluorescent reporter assay for the detection and quantification of DNA double-strand break repair.Nucleic Acids Res2020
32094185Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites.Proc Natl Acad Sci U S A2020
31425296The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis.Ann Surg2019
31358529Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer.Cancer Res2019
28838998The Neddylation Inhibitor Pevonedistat (MLN4924) Suppresses and Radiosensitizes Head and Neck Squamous Carcinoma Cells and Tumors.Mol Cancer Ther2018
29844123Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.Cancer Res2018
28525742Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.Mol Cell2017
28232384The E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.Mol Cancer Res2017
29357069Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System.Adv Exp Med Biol2017
28814434Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms.Clin Cancer Res2017
27333051Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.EBioMedicine2016
26432751Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Semin Cancer Biol2016
25035215Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.Int J Radiat Oncol Biol Phys2014
23335075Genomic instability in cancer.Cold Spring Harb Perspect Biol2013
23892434Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.Cell Cycle2013
24022480Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.J Biol Chem2013
23478445CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.Mol Cell2013
23401855The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.Mol Cell Biol2013
21212733CRL4Cdt2: master coordinator of cell cycle progression and genome stability.Cell Cycle2011
21628527Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.Mol Cell Biol2011
21757720The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein.J Biol Chem2011
20129063CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis.Mol Cell2010
20932471CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.Mol Cell2010
19440234p21 in cancer: intricate networks and multiple activities.Nat Rev Cancer2009
18794347PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.Genes Dev2008
17361108Autocatalytic phosphorylation of CDK2 at the activating Thr160.Cell Cycle2007
16687928CDK2-activating kinase (CAK): more questions than answers.Cell Cycle2006
16985065Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells.Mol Cancer Ther2006
18727504DNA replication and genomic instability.Adv Exp Med Biol2005
14699137Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.J Biol Chem2004
15199126Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.Mol Cell Biol2004
12183457Differential activation of p53 by the various adducts of mitomycin C.J Biol Chem2002
11331247Novel tumor-promoting property of tamoxifen.Cell Growth Differ2001
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Collaborators

Anindya Dutta
Co-authored papers 17
Bryce M Paschal
University of Virginia School of Medicine
Co-authored papers 3
Natalia Dworak
University of Virginia School of Medicine
Co-authored papers 3
Craig L Slingluff
University of Virginia
Co-authored papers 3
Mahmut Parlak
University of Virginia
Co-authored papers 3
Nicholas E Sherman
University of Virginia
Co-authored papers 3
Kasey Jividen
Center for Cell Signaling, University of Virginia
Co-authored papers 2
David L Brautigan
Co-authored papers 2
Luke T Oostdyk
Center for Cell Signaling, University of Virginia
Co-authored papers 2
Agnieszka Bronisz
Mossakowski Medical Research Institute, Polish Academy of Sciences
Co-authored papers 2
Chunsong Yang
Department of Pharmacy, West China Second Hospital, Sichuan University
Co-authored papers 2
Jeongwu Lee
Lerner Research Institute, Cleveland Clinic
Co-authored papers 2
Aakrosh Ratan
Center for Public Health Genomics, University of Virginia
Co-authored papers 1
Mandovi Chatterjee
Center for Cell Signaling, University of Virginia
Co-authored papers 1
Mazhar Adli
Co-authored papers 1
Stefan Bekiranov
University of Virginia
Co-authored papers 1
Philip J Ebert
Lilly Research Laboratories
Co-authored papers 1
Li Ni
Center for Cell Signaling, University of Virginia
Co-authored papers 1
Analisa DiFeo
Co-authored papers 1
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 1
Capucine Van Rechem
Stanford University School of Medicine
Co-authored papers 1
Victor H Engelhard
University of Virginia School of Medicine
Co-authored papers 1
Adam Spencer
University of Virginia
Co-authored papers 1
Vera Gorbunova
University of Rochester
Co-authored papers 1
Peter C Scacheri
Case Western Reserve University School of Medicine
Co-authored papers 1
Guo-Cheng Yuan
Dana-Farber Cancer Institute, Harvard School of Public Health
Co-authored papers 1
John C Schimenti
Co-authored papers 1
Beata Kusmider
Swiss National Centre for Competence in Research Program Chemical Biology
Co-authored papers 1
James A Wohlschlegel
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 1
Brian J Reon
University of Virginia
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Release 1.2