Author details

Full Name

Xiaodong Zhang

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36237332	Histone lysine methylation patterns in prostate cancer microenvironment infiltration: Integrated bioinformatic analysis and histological validation.	Frontiers in Oncology	2022
34758320	Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle.	Cell Reports	2021
33906046	A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.	European Journal of Medicinal Chemistry	2021
34007045	Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance.	Leukemia	2021
34219457	Discovery of a Fluorogenic Probe for In Situ Pyruvate Kinase M2 Isoform (PKM2) Labeling through Chemoselective SAr with a Binding Site Lysine Residue.	Analytical Chemistry	2021
32881291	A "Three-in-One" Multifunctional Probe for Bcl-2/Mcl-1 Profiling and Visualizing in Situ.	ChemBioChem	2021
32651234	The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients.	Journal of Biological Chemistry	2020
32175625	Structure-based design, synthesis, and evaluation of Bcl-2/Mcl-1 dual inhibitors.	Archiv der Pharmazie	2020
31669390	Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1.	European Journal of Pharmaceutical Sciences	2020
31389699	Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands.	Journal of Medicinal Chemistry	2019
31612571	Synthesis, characterization, and evaluation of novel cell-penetrating peptides based on TD-34.	J Pept Sci	2019
30982838	A novel turn-on fluorescent probe for selective sensing and imaging of glutathione in live cells and organisms.	Analyst, The	2019
30133085	Proteome-Wide Identification of On- and Off-Targets of Bcl-2 Inhibitors in Native Biological Systems by Using Affinity-Based Probes (AfBPs).	ChemBioChem	2018
25556658	Dynamic phosphorylation of CENP-A at Ser68 orchestrates its cell-cycle-dependent deposition at centromeres.	Developmental Cell	2015
24196441	CtIP is required for DNA damage-dependent induction of P21.	Cell Cycle	2014
24064232	Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction.	Journal of Ethnopharmacology	2013
21960006	Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.	EMBO Reports	2011
21840932	Cross-talk between phospho-STAT3 and PLCÎ³1 plays a critical role in colorectal tumorigenesis.	Mol Cancer Res	2011
20133777	Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.	Proc Natl Acad Sci U S A	2010
21098664	Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes.	Proc Natl Acad Sci U S A	2010
19826040	microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.	Cancer Research	2009
19251738	Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.	Genome Res	2009
18176569	Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies.	Nat Methods	2008
18644975	Tumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesion.	Molecular Cancer Research	2008
18676834	Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase.	Cancer Research	2008
17360477	Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T.	Proc Natl Acad Sci U S A	2007
16753007	High-throughput mutational analysis of the human cancer genome.	Pharmacogenomics	2006