Author details

Full Name

Eduardo D Sontag

Affiliation

ORCID

Career Start Year

1992

Papers

105

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37734322	What cannot be seen correctly in 2D visualizations of single-cell 'omics data?	Cell Syst	2023
34531364	Comment on "In vivo flow cytometry reveals a circadian rhythm of circulating tumor cells".	Light: Science and Applications	2021
33935582	Universal features of epidemic models under social distancing guidelines.	Annual Reviews in Control	2021
34031517	Derivation of stationary distributions of biochemical reaction networks via structure transformation.	Communications Biology	2021
33242489	A novel COVID-19 epidemiological model with explicit susceptible and asymptomatic isolation compartments reveals unexpected consequences of timing social distancing.	Journal of Theoretical Biology	2021
32842865	A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks.	Epigenetics	2021
34917900	A synthetic distributed genetic multi-bit counter.	iScience	2021
34567591	Maximizing average throughput in oscillatory biochemical synthesis systems: an optimal control approach.	Royal Society Open Science	2021
33215611	Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer.	Physical Biology	2020
32017536	Mathematical Models of Protease-Based Enzymatic Biosensors.	ACS Synth Biol	2020
32092050	A computational framework for a Lyapunov-enabled analysis of biochemical reaction networks.	PLoS Computational Biology	2020
32656186	Mathematical Details on a Cancer Resistance Model.	Frontiers in Bioengineering and Biotechnology	2020
32589837	Distributed Implementation of Boolean Functions by Transcriptional Synthetic Circuits.	ACS Synthetic Biology	2020
32695118	Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance.	Frontiers in Immunology	2020
33240820	Short-Term Circulating Tumor Cell Dynamics in Mouse Xenograft Models and Implications for Liquid Biopsy.	Frontiers in Oncology	2020
30779734	Multi-modality in gene regulatory networks with slow promoter kinetics.	PLoS Computational Biology	2019
31848346	In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller.	Nature Communications	2019
32103851	Stochastic analysis of genetic feedback controllers to reprogram a pluripotency gene regulatory network.	Proceedings of the American Control Conference	2019
31809500	Inferring reaction network structure from single-cell, multiplex data, using toric systems theory.	PLoS Computational Biology	2019
30745900	Immunobiochemical Reconstruction of Influenza Lung Infection-Melanoma Skin Cancer Interactions.	Frontiers in Immunology	2019
30969799	Mathematical Approach to Differentiate Spontaneous and Induced Evolution to Drug Resistance During Cancer Treatment.	JCO clinical cancer informatics	2019
29539408	Subharmonics and Chaos in Simple Periodically Forced Biomolecular Models.	Biophysical Journal	2018
32153314	Stochastic multistationarity in a model of the hematopoietic stem cell differentiation network.	Proceedings of the IEEE Conference on Decision and Control	2018
28541906	Controllability Analysis and Control Synthesis for the Ribosome Flow Model.	IEEE/ACM Transactions on Computational Biology and Bioinformatics	2018
29553576	Engineered promoters enable constant gene expression at any copy number in bacteria.	Nature Biotechnology	2018
28131824	A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Regions of Tumor or Pathogen Elimination.	Cell Systems	2017
32995506	Translation inhibition and resource balance in the TX-TL cell-free gene expression system.	Synth Biol (Oxf)	2017
28725484	Logarithmic sensing in aerotaxis.	npj Systems Biology and Applications	2017
28384175	Dynamic compensation, parameter identifiability, and equivariances.	PLoS Computational Biology	2017
28846089	Oscillatory stimuli differentiate adapting circuit topologies.	Nature Methods	2017
28716945	Evaluating optimal therapy robustness by virtual expansion of a sample population, with a case study in cancer immunotherapy.	Proc Natl Acad Sci U S A	2017
28799209	Computation-Guided Design of a Stimulus-Responsive Multienzyme Supramolecular Assembly.	Chembiochem	2017
28582397	Reduction of multiscale stochastic biochemical reaction networks using exact moment derivation.	PLoS Computational Biology	2017
28400475	An Platform for the Prediction of Clinical Response in Multiple Myeloma.	Cancer Research	2017
29291072	Multiple steady states and the form of response functions to antigen in a model for the initiation of T-cell activation.	Royal Society Open Science	2017
27986392	Solving Immunology?	Trends Immunol	2017
26900694	Non-monotonic Response to Monotonic Stimulus: Regulation of Glyoxylate Shunt Gene-Expression Dynamics in Mycobacterium tuberculosis.	PLoS Comput Biol	2016
26962028	A model for competition for ribosomes in the cell.	Journal of the Royal Society Interface	2016
27128344	Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory.	PLoS Computational Biology	2016
26420864	Discriminating direct and indirect connectivities in biological networks.	Proceedings of the National Academy of Sciences of the United States of America	2015
25569859	Fundamental limitation of the instantaneous approximation in fold-change detection models.	IET Systems Biology	2015
25850052	Silence on the relevant literature and errors in implementation.	Nat Biotechnol	2015
25080493	A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase.	Molecular Systems Biology	2014
25478700	A technique for determining the signs of sensitivities of steady states in chemical reaction networks.	IET Systems Biology	2014
24940789	Paradoxical results in perturbation-based signaling network reconstruction.	Biophys J	2014
24800863	Entrainment to periodic initiation and transition rates in a computational model for gene translation.	PLoS ONE	2014
23736683	Synthetic mammalian transgene negative autoregulation.	Molecular Systems Biology	2013
23319630	Minimization of thermodynamic costs in cancer cell invasion.	Proceedings of the National Academy of Sciences of the United States of America	2013
23528097	The energy costs of insulators in biochemical networks.	Biophys J	2013
23293140	Transient dynamic phenotypes as criteria for model discrimination: fold-change detection in Rhodobacter sphaeroides chemotaxis.	Journal of the Royal Society Interface	2013