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Author Details

Andrea Hellwig
Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg
1991
49
30
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37154843Distinct domains in Ndc1 mediate its interaction with the Nup84 complex and the nuclear membrane.J Cell Biol2023
34958875N-methyl-d-aspartate Receptor-mediated Preconditioning Mitigates Excitotoxicity in Human Induced Pluripotent Stem Cell-derived Brain Organoids.Neuroscience2022
32394429Structural characterization of an Arf dimer interface: molecular mechanism of Arf-dependent membrane scission.FEBS Lett2020
31670034Shaping the heart: Structural and functional maturation of iPSC-cardiomyocytes in 3D-micro-scaffolds.Biomaterials2020
32337703Epsin but not AP-2 supports reconstitution of endocytic clathrin-coated vesicles.FEBS Lett2020
30692915A Flow Cytometry-Based Approach for the Isolation and Characterization of Neural Stem Cell Primary Cilia.Front Cell Neurosci2019
30605680Proteomic Profiling of Mammalian COPII and COPI Vesicles.Cell Rep2019
28990420Synaptic Activity Protects Neurons Against Calcium-Mediated Oxidation and Contraction of Mitochondria During Excitotoxicity.Antioxid Redox Signal2018
29396028Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG.Mol Genet Metab2018
27590316Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system.J Thromb Haemost2016
26158910Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.Nat Commun2015
24448162Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ.Sci Rep2014
25246532Golgi phosphoprotein 3 triggers signal-mediated incorporation of glycosyltransferases into coatomer-coated (COPI) vesicles.J Biol Chem2014
24515113The nuclear calcium signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic insult.J Biol Chem2014
23691917Scission of COPI and COPII vesicles is independent of GTP hydrolysis.Traffic2013
22174410Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation.J Biol Chem2012
23341863Virus-Like Particles Harboring CCL19, IL-2 and HPV16 E7 Elicit Protective T Cell Responses in HLA-A2 Transgenic Mice.Open Virol J2012
21324056Recombinant heptameric coatomer complexes: novel tools to study isoform-specific functions.Traffic2011
21844198Several ADP-ribosylation factor (Arf) isoforms support COPI vesicle formation.J Biol Chem2011
21558372p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth.Development2011
20149155Distinct roles of myosin Va in membrane remodeling and exocytosis of secretory granules.Traffic2010
21364663Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells.Cell Death Dis2010
20685963Farnesylated nuclear proteins Kugelkern and lamin Dm0 affect nuclear morphology by directly interacting with the nuclear membrane.Mol Biol Cell2010
20124479Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.Cancer Res2010
19053060Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells.Glia2009
19940164Synaptic activity induces dramatic changes in the geometry of the cell nucleus: interplay between nuclear structure, histone H3 phosphorylation, and nuclear calcium signaling.J Neurosci2009
19414606Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores.J Cell Biol2009
17360540Differential localization of coatomer complex isoforms within the Golgi apparatus.Proc Natl Acad Sci U S A2007
16731511Experience-dependent formation and recruitment of large vesicles from reserve pool.Neuron2006
15950215Prospective isolation of late development multipotent precursors whose migration is promoted by EGFR.Dev Biol2005
15316084Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis.J Cell Sci2004
12615975Myosin Va facilitates the distribution of secretory granules in the F-actin rich cortex of PC12 cells.J Cell Sci2003
11927550Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction.EMBO J2002
14501219AN2, the mouse homologue of NG2, is a surface antigen on glial precursor cells implicated in control of cell migration.J Neurocytol2002
11518525Peptide mimics of SNARE transmembrane segments drive membrane fusion depending on their conformational plasticity.J Mol Biol2001
11433378Immunocompetent astrocytes and microglia display major differences in the processing of the invariant chain and in the expression of active cathepsin L and cathepsin S.Eur J Immunol2001
10587575A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration.Hum Mol Genet2000
11052669Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.Biochemistry2000
10681530The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions.J Biol Chem2000
10198284Selective localization of the polytopic membrane protein prominin in microvilli of epithelial cells - a combination of apical sorting and retention in plasma membrane protrusions.J Cell Sci1999
9628865Chromogranin B (secretogranin I), a neuroendocrine-regulated secretory protein, is sorted to exocrine secretory granules in transgenic mice.EMBO J1998
9463388Nup116p and nup100p are interchangeable through a conserved motif which constitutes a docking site for the mRNA transport factor gle2p.EMBO J1998
9486532Neuroepithelial cells downregulate their plasma membrane polarity prior to neural tube closure and neurogenesis.Mech Dev1997
9214641Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.EMBO J1997
9356465Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells.Proc Natl Acad Sci U S A1997
8954735Loss of occludin and functional tight junctions, but not ZO-1, during neural tube closure--remodeling of the neuroepithelium prior to neurogenesis.Dev Biol1996
7638193Neurosecretory vesicles can be hybrids of synaptic vesicles and secretory granules.Proc Natl Acad Sci U S A1995
8490154[The initial clinical experiences with a dynamic FLASH-2D sequence in tumors of the head and neck area].Rofo1993
1908779Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP-ribosyltransferase.Eur J Cell Biol1991
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Collaborators

Universitat Heidelberg
Co-authored papers 3
Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg
Co-authored papers 3
Universitat Heidelberg
Co-authored papers 3
Interdisciplinary Center for Neurosciences (IZN), Heidelberg University
Co-authored papers 2
Institute of Neurophysiology, University of Cologne
Co-authored papers 1
University of Augsburg
Co-authored papers 1
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB
Co-authored papers 1
Medical University of Vienna
Co-authored papers 1
Co-authored papers 1
National Heart Lung and Blood Institute, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Research Centre, Ananda College
Co-authored papers 1
Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg
Co-authored papers 1
Co-authored papers 1
Heidelberg University
Co-authored papers 1
Federal Institute for Drugs and Medical Devices (BfArM)
Co-authored papers 1
Heidelberg University Biochemistry Center, Heidelberg University
Co-authored papers 1
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 1
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University
Co-authored papers 1
Berlin Institute of Health (BIH) and Charite
Co-authored papers 1
Max-Planck Institute of Biochemistry
Co-authored papers 1