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Author Details

Alex K Shalek
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
2005
155
55
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37169965Comparative analysis of cell-cell communication at single-cell resolution.Nat Biotechnol2024
37169965Comparative analysis of cell-cell communication at single-cell resolution.Nat Biotechnol2024
36596894NIAID workshop on T cell technologies.Nat Immunol2023
37843832CD8+ lymphocytes are critical for early control of tuberculosis in macaques.J Exp Med2023
37745424Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infection.medRxiv2023
37732484Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress.Arterioscler Thromb Vasc Biol2023
38077315Identification of drug candidates targeting monocyte reprogramming in people living with HIV.Front Immunol2023
38077056Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival.bioRxiv2023
37961527Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.bioRxiv2023
38055798Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for <i>Mycobacterium tuberculosis</i>.Sci Transl Med2023
38047068Early cellular and molecular signatures correlate with severity of West Nile virus infection.iScience2023
37158243Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients.Hepatology2023
37076617PI3Kβ controls immune evasion in PTEN-deficient breast tumours.Nature2023
36708230An ex vivo ovulation system enables the discovery of novel ovulatory pathways and nonhormonal contraceptive candidatesâ¿ .Biol Reprod2023
36495445Profiling Transcriptional Heterogeneity with Seq-Well S<sup>3</sup>: A Low-Cost, Portable, High-Fidelity Platform for Massively Parallel Single-Cell RNA-Seq.Methods Mol Biol2023
37075115Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation.Sci Adv2023
36747859Compressed phenotypic screens for complex multicellular models and high-content assays.bioRxiv2023
37443254Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.Nat Genet2023
36459568Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.Cancer Res2023
37502895Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.bioRxiv2023
37498173Vitrification preserves follicular transcriptomic dynamics during ex vivo ovulationâ¿ .Biol Reprod2023
36596894NIAID workshop on T cell technologies.Nat Immunol2023
38077315Identification of drug candidates targeting monocyte reprogramming in people living with HIV.Front Immunol2023
38077056Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival.bioRxiv2023
37961527Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.bioRxiv2023
37745424Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infection.medRxiv2023
37843832CD8+ lymphocytes are critical for early control of tuberculosis in macaques.J Exp Med2023
38055798Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for <i>Mycobacterium tuberculosis</i>.Sci Transl Med2023
37502895Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.bioRxiv2023
38047068Early cellular and molecular signatures correlate with severity of West Nile virus infection.iScience2023
37732484Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress.Arterioscler Thromb Vasc Biol2023
37498173Vitrification preserves follicular transcriptomic dynamics during ex vivo ovulationâ¿ .Biol Reprod2023
37158243Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients.Hepatology2023
37443254Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.Nat Genet2023
37076617PI3Kβ controls immune evasion in PTEN-deficient breast tumours.Nature2023
37075115Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation.Sci Adv2023
36747859Compressed phenotypic screens for complex multicellular models and high-content assays.bioRxiv2023
36708230An ex vivo ovulation system enables the discovery of novel ovulatory pathways and nonhormonal contraceptive candidatesâ¿ .Biol Reprod2023
36459568Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.Cancer Res2023
36495445Profiling Transcriptional Heterogeneity with Seq-Well S<sup>3</sup>: A Low-Cost, Portable, High-Fidelity Platform for Massively Parallel Single-Cell RNA-Seq.Methods Mol Biol2023
35169794Comparative analysis of cell-cell communication at single-cell resolution.bioRxiv2022
36044598Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation.Sci Transl Med2022
35590143JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.Med2022
35705813Deciphering the immunopeptidome in vivo reveals new tumour antigens.Nature2022
35899878Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation.Reproduction2022
35443155A single-cell liver atlas of Plasmodium vivax infection.Cell Host Microbe2022
36087201Enriching and Characterizing T Cell Repertoires from 3' Barcoded Single-Cell Whole Transcriptome Amplification Products.Methods Mol Biol2022
35377806Cellular and transcriptional diversity over the course of human lactation.Proc Natl Acad Sci U S A2022
36330531HIV specific CD8<sup>+</sup> T<sub>RM</sub>-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.Front Immunol2022
35483355Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.Immunity2022
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Collaborators

Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 32
Jose Ordovas-Montanes
Co-authored papers 25
Rahul Satija
Center for Genomics and Systems Biology, New York University
Co-authored papers 13
Orit Rozenblatt-Rosen
Co-authored papers 13
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 12
Nir Yosef
Center for Computational Biology, University of California berkeley
Co-authored papers 11
Bonnie Berger
Massachusetts Institute of Technology
Co-authored papers 8
Bruce D Walker
Ragon Institute of Mass General
Co-authored papers 8
Itay Tirosh
Weizmann Institute of Medical Sciences
Co-authored papers 7
Tyler Jacks
Co-authored papers 6
Alexandra-Chloé Villani
Co-authored papers 6
Ramnik J Xavier
Broad Institute of MIT and Harvard
Co-authored papers 5
Bryan D Bryson
Massachusetts Institute of Technology, USA The Ragon Institute of MGH
Co-authored papers 5
Peter S Winter
Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School
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Orr Ashenberg
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Ido Amit
Weizmann Institute of Science
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JoAnne L Flynn
Co-authored papers 4
Mario L Suv??
Broad Institute of MIT and Harvard
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Eric S Lander
Vanderbilt-Ingram Cancer Center, Vanderbilt University
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Bradley E Bernstein
Broad Institute of MIT and Harvard
Co-authored papers 4
Winston Hide
Harvard Medical School
Co-authored papers 3
Ayshwarya Subramanian
Broad Institute of MIT and Harvard
Co-authored papers 3
Ioannis S Vlachos
Harvard Medical School
Co-authored papers 3
Eliezer M Van Allen
Dana-Farber Cancer Institute
Co-authored papers 3
Mehrtash Babadi
Co-authored papers 3
Jesse M Engreitz
Co-authored papers 3
Michal Slyper
Co-authored papers 3
Levi A Garraway
Broad Institute of Harvard and MIT
Co-authored papers 3
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 3
Garry P Nolan
Stanford University School of Medicine
Co-authored papers 3
Release 1.2