Author details

Full Name

Nathan D Trinklein

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36016696	A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer.	Oncoimmunology	2022
33818299	TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL.	MAbs	2021
34011961	A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells.	Sci Rep	2021
34088740	Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release.	J Immunother Cancer	2021
32152289	Author Correction: Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains.	Nature Communications	2020
32351885	Perspective: Designing T-Cell Engagers With Better Therapeutic Windows.	Frontiers in Oncology	2020
31941907	Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains.	Nature Communications	2020
30666250	Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies.	Front Immunol	2019
30698484	Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies.	MAbs	2019
29740455	Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.	Front Immunol	2018
29485921	When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.	mAbs	2018
27423190	A Single Human Papillomavirus Vaccine Dose Improves B Cell Memory in Previously Infected Subjects.	EBioMedicine	2016
25275310	Genome-wide discovery of drug-dependent human liver regulatory elements.	PLoS Genet	2014
23050045	Identification of a Functional In Vivo p53 Response Element in the Coding Sequence of the Xeroderma Pigmentosum Group C Gene.	Genes Cancer	2012
22951020	Functional analysis of transcription factor binding sites in human promoters.	Genome Biol	2012
21637794	Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.	PLoS Genet	2011
21402708	Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.	J Biol Chem	2011
21988797	Identifying targets of human micrornas with the LightSwitch Luciferase Assay System using 3'UTR-reporter constructs and a microRNA mimic in adherent cells.	Journal of Visualized Experiments	2011
20501695	Sequence features that drive human promoter function and tissue specificity.	Genome Res	2010
19860899	A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays.	BMC Genomics	2009
18258921	Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets.	Genome Res	2008
18020712	The ets-related transcription factor GABP directs bidirectional transcription.	PLoS Genet	2007
17568000	Transcription factor binding and modified histones in human bidirectional promoters.	Genome Res	2007
17567992	Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome.	Genome Res	2007
17200232	Serum response factor binding sites differ in three human cell types.	Genome Res	2007
17571346	Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.	Nature	2007
16344566	Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome.	Genome Res	2006
15899964	Direct isolation and identification of promoters in the human genome.	Genome Res	2005
15004229	Diverse and specific gene expression responses to stresses in cultured human cells.	Mol Biol Cell	2004
15270074	Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal stress and differentiation.	Cell Stress Chaperones	2004
14707170	An abundance of bidirectional promoters in the human genome.	Genome Res	2004
14668476	The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response.	Mol Biol Cell	2004
12566409	Identification and functional analysis of human transcriptional promoters.	Genome Res	2003