Author details

Full Name

Oleg Ursu

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35149761	Machine learning prediction and tau-based screening identifies potential Alzheimer's disease genes relevant to immunity.	Commun Biol	2022
35192366	PepSeA: Peptide Sequence Alignment and Visualization Tools to Enable Lead Optimization.	Journal of Chemical Information and Modeling	2022
33151287	DrugCentral 2021 supports drug discovery and repositioning.	Nucleic Acids Res	2021
34215797	Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems.	Sci Rep	2021
32792589	Publisher Correction: A mass spectrometry-based proteome map of drug action in lung cancer cell lines.	Nature Chemical Biology	2020
32690943	A mass spectrometry-based proteome map of drug action in lung cancer cell lines.	Nature Chemical Biology	2020
31048796	Novel drug targets in 2018.	Nat Rev Drug Discov	2019
30371892	DrugCentral 2018: an update.	Nucleic Acids Res	2019
30848459	How to Prepare a Compound Collection Prior to Virtual Screening.	Methods Mol Biol	2019
27856785	Chronic obstructive pulmonary disease phenotypes using cluster analysis of electronic medical records.	Health Informatics J	2018
29567993	Unexplored therapeutic opportunities in the human genome.	Nat Rev Drug Discov	2018
29177837	High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.	Methods Mol Biol	2018
29472638	Unexplored therapeutic opportunities in the human genome.	Nat Rev Drug Discov	2018
29746086	Activation of Rho Family GTPases by Small Molecules.	ACS Chem Biol	2018
29232168	High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining.	SLAS Discovery	2018
28131723	Protein biomarker druggability profiling.	J Biomed Inform	2017
29016968	Formalizing drug indications on the road to therapeutic intent.	J Am Med Inform Assoc	2017
28398460	TIN-X: target importance and novelty explorer.	Bioinformatics	2017
29122012	Drug target ontology to classify and integrate drug discovery data.	J Biomed Semantics	2017
27789690	DrugCentral: online drug compendium.	Nucleic Acids Res	2017
27910877	A comprehensive map of molecular drug targets.	Nat Rev Drug Discov	2017
27903890	Pharos: Collating protein information to shed light on the druggable genome.	Nucleic Acids Res	2017
27736015	Estimation of Maximum Recommended Therapeutic Dose Using Predicted Promiscuity and Potency.	Clin Transl Sci	2016
27239230	Badapple: promiscuity patterns from noisy evidence.	J Cheminform	2016
27182629	BDDCS, the Rule of 5 and drugability.	Adv Drug Deliv Rev	2016
27213018	Erratum to: Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes.	J Cheminform	2016
27074918	Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation.	Sci Rep	2016
26442911	Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.	J Biomol Screen	2016
26247207	A Pan-GTPase Inhibitor as a Molecular Probe.	PLoS ONE	2015
25378583	FRET detection of lymphocyte function-associated antigen-1 conformational extension.	Mol Biol Cell	2015
25813550	Development and validation of a clinical prediction rule for candidemia in hospitalized patients with severe sepsis and septic shock.	Journal of Critical Care	2015
25760340	Therapeutic options and emerging alternatives for multidrug resistant staphylococcal infections.	Curr Pharm Des	2015
25381253	A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants.	Journal of Biomolecular Screening	2015
26558612	Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.	PLoS One	2015
26346852	CHEMICAL AND BIOLOGICAL DESCRIPTOR INTEGRATION IMPROVES COMPUTATIONAL MODELING OF <i>IN VIVO</i> RAT TOXICITY.	Rev Roum Chim	2015
25027381	A high throughput flow cytometric assay platform targeting transporter inhibition.	Drug Discov Today Technol	2014
23382385	Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.	J Biol Chem	2013
22923785	A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry.	J Biomol Screen	2013
23890825	Emerging trends in the discovery of natural product antibacterials.	Curr Opin Pharmacol	2013
23794735	The CARLSBAD database: a confederated database of chemical bioactivities.	Database (Oxford)	2013
23470221	Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.	Anal Biochem	2013
23303535	A chemogenomic analysis of ionization constants--implications for drug discovery.	ChemMedChem	2013
22260433	Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.	ACS Chem Biol	2012
22486388	A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.	ACS Chem Biol	2012
22368688	Drug Repurposing from an Academic Perspective.	Drug Discov Today Ther Strateg	2011
22287994	Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.	Mol Inform	2011
20156991	iPHACE: integrative navigation in pharmacological space.	Bioinformatics	2010
20726597	Model-free drug-likeness from fragments.	J Chem Inf Model	2010
19754304	Conformational mAb as a tool for integrin ligand discovery.	Assay Drug Dev Technol	2009
19536101	A crowdsourcing evaluation of the NIH chemical probes.	Nat Chem Biol	2009