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Author Details

Patrick C O'Leary
University of California San Francisco
2010
12
7
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37131711A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis <i>in vivo</i>.bioRxiv2023
37651466A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.PLoS Pathog2023
36273492Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2.Cancer Res2022
35439318A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor.Mol Cancer Ther2022
36002574RASA2 ablation in T cells boosts antigen sensitivity and long-term function.Nature2022
30305055Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL.BMC Cancer2018
30287919Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents.Br J Cancer2018
25746038High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.Melanoma Res2015
25011585Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.Breast Cancer Res2014
23547718Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer.BMC Cancer2013
22646761Generation of a new bioluminescent model for visualisation of mammary tumour development in transgenic mice.BMC Cancer2012
20465595Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.Pigment Cell Melanoma Res2010
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Collaborators

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Uppsala University
Co-authored papers 3
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
Gladstone Institutes
Co-authored papers 2
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Co-authored papers 2
University of California san francisco
Co-authored papers 2
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Co-authored papers 2
University of California san francisco
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UCD Conway Institute, University College Dublin
Co-authored papers 1
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Gladstone Institutes
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Gladstone-UCSF Institute of Genomic Immunology
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Quantitative Biosciences Institute (QBI), University of California San Francisco
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Gladstone Institute of Virology, Gladstone Institutes
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