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Author Details

Christopher W Akey
Boston University, Chobanian and Avedisian School of Medicine
1977
54
37
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37738963Implications of a multiscale structure of the yeast nuclear pore complex.Mol Cell2023
34982960Comprehensive structure and functional adaptations of the yeast nuclear pore complex.Cell2022
29539637Integrative structure and functional anatomy of a nuclear pore complex.Nature2018
29765111New insights into apoptosome structure and function.Cell Death Differ2018
27916517A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation.Structure2017
28510448Oxidized or Reduced Cytochrome c and Axial Ligand Variants All Form the Apoptosome in Vitro.Biochemistry2017
27697150A near atomic structure of the active human apoptosome.Elife2016
24153188Structure of the SecY channel during initiation of protein translocation.Nature2014
23561633Apoptosome structure, assembly, and procaspase activation.Structure2013
23913920Tango7 directs cellular remodeling by the Drosophila apoptosome.Genes Dev2013
23850453IcmQ in the Type 4b secretion system contains an NAD+ binding domain.Structure2013
23521171Changes in Apaf-1 conformation that drive apoptosome assembly.Biochemistry2013
21220123Structure of the Drosophila apoptosome at 6.9 å resolution.Structure2011
21863821Crystal structure and function of human nucleoplasmin (npm2): a histone chaperone in oocytes and embryos.Biochemistry2011
21827945The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3.Structure2011
20462491Structure of an apoptosome-procaspase-9 CARD complex.Structure2010
20947011The NPC-transporter, a ghost in the machine.Structure2010
19368892Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila.Structure2009
18400176Structure of the mammalian 80S ribosome at 8.7 A resolution.Structure2008
18611385Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome.Structure2008
18158904Ribosome binding of a single copy of the SecY complex: implications for protein translocation.Mol Cell2007
16310803Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer.J Mol Biol2006
15811380Architecture of the ribosome-channel complex derived from native membranes.J Mol Biol2005
16271896A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform.Structure2005
15313231Structural insight into the protein translocation channel.Curr Opin Struct Biol2004
15583381Purification, crystallization and preliminary X-ray analysis of the N-terminal domain of NO38, a nucleolar protein from Xenopus laevis.Acta Crystallogr D Biol Crystallogr2004
15576029The structure and function of Xenopus NO38-core, a histone chaperone in the nucleolus.Structure2004
12575937The crystal structure of Drosophila NLP-core provides insight into pentamer formation and histone binding.Structure2003
12581654Histone chaperones and nucleosome assembly.Curr Opin Struct Biol2003
11864614Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.Mol Cell2002
12460584Structure of the mammalian ribosome-channel complex at 17A resolution.J Mol Biol2002
11684019The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.Mol Cell2001
11106759The structure of ribosome-channel complexes engaged in protein translocation.Mol Cell2000
10926511A comparison of the yeast and rabbit 80 S ribosome reveals the topology of the nascent chain exit tunnel, inter-subunit bridges and mammalian rRNA expansion segments.J Mol Biol2000
9917412The bacterial SecY/E translocation complex forms channel-like structures similar to those of the eukaryotic Sec61p complex.J Mol Biol1999
9659919Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications.Mol Cell1998
9405308Active nuclear pore complexes in Chironomus: visualization of transporter configurations related to mRNP export.J Cell Sci1998
9215630The yeast spindle pole body is assembled around a central crystal of Spc42p.Cell1997
8929540Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.Cell1996
7739040Structural plasticity of the nuclear pore complex.J Mol Biol1995
8314837Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy.J Cell Biol1993
1720335Probing the structure and function of the nuclear pore complex.Semin Cell Biol1991
2207242Visualization of transport-related configurations of the nuclear pore transporter.Biophys J1990
2475512Protein import through the nuclear pore complex is a multistep process.J Cell Biol1989
2768344Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy.J Cell Biol1989
3112411The innermost chorionic layer of Drosophila. II. Three-dimensional structure determination of the 90 degrees crystal form by electron microscopy.J Mol Biol1987
3112410The innermost chorionic layer of Drosophila. I. The role of chorin octamers in the formation of a family of interdigitating crystalline plates.J Mol Biol1987
2908457Electron microscopy of single molecules and crystals of F1-ATPases.Methods Enzymol1986
6474594Trigonal catalase crystals: a new molecular packing assignment obtained from sections preserved with tannic acid.Ultramicroscopy1984
6219110Electron microscopy of beef heart F1-ATPase crystals.J Biol Chem1983
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Collaborators

Jean-Fran??ois M??n??tret
IGBMC (Institute of Genetics and of Molecular and Cellular Biology)
Co-authored papers 12
Steven J Ludtke
Baylor College of Medicine
Co-authored papers 10
Michael P Rout
The Rockefeller University
Co-authored papers 5
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 4
Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 4
Javier Fernandez-Martinez
The Rockefeller University
Co-authored papers 3
Ilona Nudelman
The Rockefeller University
Co-authored papers 3
James C Gumbart
Georgia Institute of Technology
Co-authored papers 3
Brian T Chait
The Rockefeller University
Co-authored papers 3
Ignacia Echeverria
University of California san francisco
Co-authored papers 3
Junjie Wang
The Rockefeller University
Co-authored papers 3
Christna Ouch
Boston University School of Medicine, University of Massachusetts Medical School
Co-authored papers 2
Zhiheng Yu
Howard Hughes Medical Institute
Co-authored papers 2
Preethi Chandramouli
Harvard University
Co-authored papers 2
Steven P Gygi
Harvard Medical School
Co-authored papers 2
Shuchismita Dutta
The State University of New Jersey
Co-authored papers 2
John E Heuser
Washington University School of Medicine
Co-authored papers 2
Jay R Unruh
Stowers Institute for Medical Research
Co-authored papers 2
Kangkang Song
University of Massachusetts Chan Medical School
Co-authored papers 1
Roxana Mironska
The Rockefeller University
Co-authored papers 1
Michael Jason de la Cruz
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Thurston Herricks
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 1
Erica Y Jacobs
The Rockefeller University, St John's University
Co-authored papers 1
Joanna A Hogan
Indiana University
Co-authored papers 1
Azraa S Chaudhury
Geisinger Medical Center
Co-authored papers 1
Narayanan Eswar
University of California at San Francisco
Co-authored papers 1
Digvijay Singh
University of California San Diego
Co-authored papers 1
Daniel Salzberg
University of California san francisco
Co-authored papers 1
Joseph M Varberg
Stowers Institute for Medical Research
Co-authored papers 1
John V Kilmartin
Medical Research Council Laboratory of Molecular Biology
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Release 1.2