Author details

Full Name

John Danesh

Affiliation

ORCID

Career Start Year

1988

Papers

325

H Index

131

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37804448	Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries.	Eur J Nutr	2024
36720882	Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants.	Sci Data	2023
37679551	Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
37596262	A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.	Nat Commun	2023
37647652	A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.	Blood	2023
37725834	Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease.	Diabetes Care	2023
37563721	Evaluation of interventions to prevent vasovagal reactions among whole blood donors: rationale and design of a large cluster randomised trial.	Trials	2023
37563310	Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37367415	Risk Factors of Secondary Cardiovascular Events in a Multi-Ethnic Asian Population with Acute Myocardial Infarction: A Retrospective Cohort Study from Malaysia.	J Cardiovasc Dev Dis	2023
37104291	A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes: Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study.	PLoS Med	2023
36991119	An atlas of genetic scores to predict multi-omic traits.	Nature	2023
37494011	Association of Longer Leukocyte Telomere Length With Cardiac Size, Function, and Heart Failure.		2023
37291107	South Asian medical cohorts reveal strong founder effects and high rates of homozygosity.	Nat Commun	2023
35072137	Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease.	Cell Genom	2022
36314129	Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses.	Circulation	2022
36048760	Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.	PLoS Genet	2022
36240095	Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.	Neurology	2022
35388009	Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
36357675	Rare and common genetic determinants of metabolic individuality and their effects on human health.	Nat Med	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
35381005	Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank.	PLoS One	2022
35381001	Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.	PLoS Genetics	2022
35880304	Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank.	J Bone Miner Res	2022
35568032	Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites.	Am J Hum Genet	2022
35685390	Modifiable traits, healthy behaviours, and leukocyte telomere length: a population-based study in UK Biobank.	Lancet Healthy Longev	2022
35403197	Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study.	Eur J Prev Cardiol	2022
36446790	Genetically personalised organ-specific metabolic models in health and disease.	Nat Commun	2022
36253349	Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.	Nat Commun	2022
37117760	Measurement and initial characterization of leukocyte telomere length in 474,074 participants in UK Biobank.	Nat Aging	2022
35064169	Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.	Sci Rep	2022
35297226	Association of shorter leucocyte telomere length with risk of frailty.	J Cachexia Sarcopenia Muscle	2022
34670632	Milk intake and incident stroke and CHD in populations of European descent: a Mendelian randomisation study.	Br J Nutr	2022
35264566	Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
35142634	Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study.	JMIR Res Protoc	2022
34753797	An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.	Diabetes	2022
34528757	Risk factors and prediction models for incident heart failure with reduced and preserved ejection fraction.	ESC Heart Fail	2021
33692568	The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation.	Nat Genet	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
34226637	Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates.	Int J Obes (Lond)	2021
33837377	Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.	Nat Med	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
34098341	Accuracy of four lateral flow immunoassays for anti SARS-CoV-2 antibodies: a head-to-head comparative study.	eBioMedicine	2021
33444330	Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses.	PLoS Med	2021
33822779	Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.	PLoS Genet	2021
34135082	Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study.	J Am Soc Nephrol	2021
34304048	Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank.	EBioMedicine	2021
33351885	Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis.	Eur Heart J	2021
33341984	Comparison of four methods to measure haemoglobin concentrations in whole blood donors (COMPARE): A diagnostic accuracy study.	Transfus Med	2021
33414548	A cross-platform approach identifies genetic regulators of human metabolism and health.	Nat Genet	2021