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Author Details

Nina Fenouille
Universite Paris Cite, INSERM, CNRS
2008
25
19
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35750691A multiparametric niche-like drug screening platform in acute myeloid leukemia.Blood Cancer J2022
35474100Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.Leukemia2022
35668193P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.Nat Cancer2022
33790022Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.Sci Transl Med2021
32826232The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.Cancer Discov2020
29233875To be or not to be cell autonomous? Autophagy says both.Essays Biochem2017
28191887The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Nat Med2017
27325891Targeting MTHFD2 in acute myeloid leukemia.J Exp Med2016
27455953BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.J Exp Med2016
25737277A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth.Genes Dev2015
25925867Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis.Nat Commun2015
24525236SYK is a critical regulator of FLT3 in acute myeloid leukemia.Cancer Cell2014
25058423A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function.Cell Death Dis2014
22069124Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts.J Pathol2012
22860231When autophagy meets cancer through p62/SQSTM1.Am J Cancer Res2012
22911700The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.PLoS One2012
22467682Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.J Mol Cell Biol2012
21996743Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells.Oncogene2012
20955243The p53/p21Cip1/â¿¿Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.Pigment Cell Melanoma Res2011
22101270Mechanism of action of the multikinase inhibitor Foretinib.Cell Cycle2011
21685937SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.Oncogene2011
20103647Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation.Cancer Res2010
21098700Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.Cancer Res2010
19293188Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.Cancer Res2009
18182997Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells.Br J Cancer2008
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Collaborators

Alexandre Puissant
Universite de Paris, INSERM, CNRS
Co-authored papers 17
Patrick Auberger
Universite Cote d'Azur, INSERM U5
Co-authored papers 10
Arnaud Jacquel
Universite Cote d'Azur, INSERM U5
Co-authored papers 6
Gabriela Alexe
Dana-Farber Cancer Institute
Co-authored papers 6
Christopher F Bassil
Duke University School of Medicine Durham
Co-authored papers 6
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 6
Gaetano Sodaro
Universite Paris Cite, INSERM, CNRS
Co-authored papers 5
Yana Pikman
Dana Farber Cancer Institute
Co-authored papers 5
Lina Benajiba
Universite de Paris, Inserm CIC 1427
Co-authored papers 4
Richard M Stone
Dana Farber Cancer Institute
Co-authored papers 4
Thomas Cluzeau
Universite Nice Cote d'azur, CHU de Nice
Co-authored papers 4
Raphael Itzykson
Universite Paris Cite, INSERM, CNRS
Co-authored papers 4
Daniel J DeAngelo
Dana-Farber Cancer Institute
Co-authored papers 4
Antoine Forget (CM4AI)
University of California San Francisco
Co-authored papers 3
Herv?? Dombret
Institut de Recherche Saint-Louis, Universite de Paris
Co-authored papers 3
Reinaldo Dal Bello
Universite Paris Cite, INSERM, CNRS
Co-authored papers 3
Kris C Wood
Duke University
Co-authored papers 2
Matthieu Duchmann
Assistance Publique-Hopitaux de Paris, Universite de Paris
Co-authored papers 2
Angela Su
The Broad Institute of MIT and Harvard
Co-authored papers 2
Thorsten Braun
Centre Hospitalier Universitaire Hopital Avicenne
Co-authored papers 2
Emmanuel Raffoux
Universite Paris Diderot
Co-authored papers 2
Camille Lobry
INSERM U1170, Universite Paris Saclay
Co-authored papers 2
Kevin H Lin
Duke University
Co-authored papers 2
Emmanuelle Clappier
Saint-Louis Hospital
Co-authored papers 2
Jeannig Berrou
Universite Paris Cite, Institut de Recherche Saint-Louis
Co-authored papers 2
Claude Preudhomme
Lille University Hospital, INSERM UMR-S7, CNRS UMR9020, Lille University.
Co-authored papers 2
Lionel Ad??s
Assistance Publique des Hopitaux de Paris (AP-HP)
Co-authored papers 2
Cl??mentine Chauvel
Universite Paris Cite, INSERM, CNRS
Co-authored papers 2
Frank Ling
INSERM UMR , St Louis Hospital, University of Paris
Co-authored papers 1
Bryann Pardieu
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
Release 1.2