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Author Details

Nehad M Alajez
College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
2004
108
32
PMIDPaper TitleJournal TitlePublished Year
36749553iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes.Stem Cell Rev Rep2023
37670346Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells.Cell Commun Signal2023
37908488High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder.Front Mol Neurosci2023
37511368Targeted MicroRNA Profiling Reveals That Exendin-4 Modulates the Expression of Several MicroRNAs to Reduce Steatosis in HepG2 Cells.Int J Mol Sci2023
37770979Therapeutic targeting of the TPX2/TTK network in colorectal cancer.Cell Commun Signal2023
37727755Long non-coding RNA AC099850.4 correlates with advanced disease state and predicts worse prognosis in triple-negative breast cancer.Front Med (Lausanne)2023
37190091Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes.Cells2023
37175824Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia.Int J Mol Sci2023
37108604Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study.Int J Mol Sci2023
37438342Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks.Cell Death Dis2023
37400525Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation.Sci Rep2023
35328807Identification of Novel Circulating miRNAs in Patients with Acute Ischemic Stroke.Int J Mol Sci2022
35643221Long non-coding RNA and RNA-binding protein interactions in cancer: Experimental and machine learning approaches.Semin Cancer Biol2022
36613546Circulating MicroRNA Profiling Identifies Distinct MicroRNA Signatures in Acute Ischemic Stroke and Transient Ischemic Attack Patients.Int J Mol Sci2022
36277770Identification of distinct circulating microRNAs in acute ischemic stroke patients with type 2 diabetes mellitus.Front Cardiovasc Med2022
36142814Identification of a Gene Panel Predictive of Triple-Negative Breast Cancer Response to Neoadjuvant Chemotherapy Employing Transcriptomic and Functional Validation.Int J Mol Sci2022
35893227LncRNA-Based Classification of Triple Negative Breast Cancer Revealed Inherent Tumor Heterogeneity and Vulnerabilities.Noncoding RNA2022
36354097Reciprocal interplays between MicroRNAs and pluripotency transcription factors in dictating stemness features in human cancers.Semin Cancer Biol2022
32727251Transcriptomic Profiling of Circulating HLA-DR<sup>-</sup> Myeloid Cells, Compared with HLA-DR<sup>+</sup> Myeloid Antigen-presenting Cells.Immunol Invest2021
33898797Identification of PBMC-based molecular signature associational with COVID-19 disease severity.Heliyon2021
33863870COVID-19: complexity of disease severity revealed by systemic and localized single cell immune atlas.Signal Transduct Target Ther2021
33665229Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel.Mol Ther Methods Clin Dev2021
33495450Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy.Cell Death Discov2021
34959629Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression.Pharmaceuticals (Basel)2021
34703883Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq.Mol Ther Oncolytics2021
34565361Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition.Cancer Cell Int2021
34771513Molecular Classification of Breast Cancer Utilizing Long Non-Coding RNA (lncRNA) Transcriptomes Identifies Novel Diagnostic lncRNA Panel for Triple-Negative Breast Cancer.Cancers (Basel)2021
34326372Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling.Sci Rep2021
34262080Integrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer.Sci Rep2021
31271889SOX4: Epigenetic regulation and role in tumorigenesis.Semin Cancer Biol2020
31801817Pembrolizumab Interferes with the Differentiation of Human FOXP3<sup>+</sup>-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR.J Immunol2020
31978617Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells.Bone2020
31941522Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer.Clin Epigenetics2020
31733291Noncoding RNAs as potential mediators of resistance to cancer immunotherapy.Semin Cancer Biol2020
33312958RNA-Seq Analysis of Colorectal Tumor-Infiltrating Myeloid-Derived Suppressor Cell Subsets Revealed Gene Signatures of Poor Prognosis.Front Oncol2020
33138195Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19.Cells2020
32882823Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2.Biology (Basel)2020
32646047Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response.Genes (Basel)2020
32984004Transcriptomic Analyses of Myeloid-Derived Suppressor Cell Subsets in the Circulation of Colorectal Cancer Patients.Front Oncol2020
32922961MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway.Cell Death Discov2020
32393769Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner.Cell Death Dis2020
32509578MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM.Front Oncol2020
30993013CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors.Cell Death Discov2019
31871467Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells.Stem Cells Int2019
31835892Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients.Cancers (Basel)2019
31767956Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation.Sci Rep2019
31349612PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer.Cancers (Basel)2019
31263577Long non-coding RNA (lncRNA) transcriptional landscape in breast cancer identifies LINC01614 as non-favorable prognostic biomarker regulated by TGFβ and focal adhesion kinase (FAK) signaling.Cell Death Discov2019
31548560Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo.Sci Rep2019
31620367Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer.Front Oncol2019
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Collaborators

Fei-Fei Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 22
Wei Shi
Research Institute, Princess Margaret Cancer Centre
Co-authored papers 16
Angela B Y Hui
Stanford University
Co-authored papers 11
Brian O'Sullivan
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 9
Carlo Bastianutto
University of Toronto
Co-authored papers 6
John Waldron
University of Toronto, Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Jeff P Bruce
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Michael Milosevic
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Anthony Fyles
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Jian-Hua Li
th Hospital
Co-authored papers 2
Nico van Rooijen
Co-authored papers 2
John C Bell
Ottawa Hospital Research Institute
Co-authored papers 2
Robert G Bristow
University of Toronto
Co-authored papers 2
Wei Xu
Princess Margaret Cancer Centre
Co-authored papers 2
Bayardo Perez-Ordonez
University Health Network
Co-authored papers 1
David R McCready
University of Toronto, University Health Network
Co-authored papers 1
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 1
Christine How
Ontario Cancer Institute, University Health Network (UHN)
Co-authored papers 1
Peter P Liu
Co-authored papers 1
Kate Gerster
Ontario Cancer Institute
Co-authored papers 1
Rui Yan
University of Groningen, University Medical Center Groningen
Co-authored papers 1
Levi Waldron
City University of New York School of Public Health
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Daniel Durocher
The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 1
Tanvir Alam
College of Science and Engineering, Hamad Bin Khalifa University
Co-authored papers 1
Blaise A Clarke
University of Toronto.
Co-authored papers 1
Jeffrey A Medin
Medical College of Wisconsin
Co-authored papers 1
Shao Hui Huang
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 1
Andrew J Evans
Princess Margaret Cancer Center, University Health Network.
Co-authored papers 1
Release 1.2