Author details

Full Name

Leor S Weinberger

Affiliation

Gladstone/UCSF Center for Cell Circuitry, Gladstone Institutes

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37300530	Expression of thioredoxin-1 in the ASJ neuron corresponds with and enhances intrinsic regenerative capacity under lesion conditioning in C.â¿¿elegans.	FEBS Lett	2023
37116472	Disrupting autorepression circuitry generates ''open-loop lethality'' to yield escape-resistant antiviral agents.	Cell	2023
35082446	Brahma safeguards canalization of cardiac mesoderm differentiation.	Nature	2022
35561685	Disrupting autorepression circuitry generates "open-loop lethality" to yield escape-resistant antiviral agents.	Cell	2022
36074824	A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.	Proc Natl Acad Sci U S A	2022
35982679	A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.	bioRxiv	2022
33468683	RanDeL-Seq: a High-Throughput Method to Map Viral <i>cis</i>- and <i>trans</i>-Acting Elements.	mBio	2021
33735616	Evaluation of Singer etÂ al.: Technical points on analyzing viral replication kinetics in single cells.	Cell Syst	2021
34838159	Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance.	Cell	2021
34301855	A DNA repair pathway can regulate transcriptional noise to promote cell fate transitions.	Science	2021
32358201	Noise-driven cellular heterogeneity in circadian periodicity.	Proc Natl Acad Sci U S A	2020
32632017	A molecular mechanism for probabilistic bet hedging and its role in viral latency.	Proc Natl Acad Sci U S A	2020
32670890	The HSV-1 ICP4 Transcriptional Auto-Repression Circuit Functions as a Transcriptional "Accelerator" Circuit.	Front Cell Infect Microbiol	2020
31222776	Post-Transcriptional Noise Control.	Bioessays	2019
31668804	Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform.	Cell	2019
31951580	HIV Latency: Stochastic across Multiple Scales.	Cell Host Microbe	2019
29754821	A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization.	Cell	2018
30243562	Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability.	Cell Syst	2018
30150412	Feedback-mediated signal conversion promotes viral fitness.	Proc Natl Acad Sci U S A	2018
28800289	Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.	Annu Rev Virol	2017
29226181	A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus.	Bio Protoc	2017
29045398	Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.	PLoS Biol	2017
28591615	Transient Thresholding: A Mechanism Enabling Noncooperative Transcriptional Circuitry to Form a Switch.	Biophys J	2017
27152856	Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals.	PLoS Comput Biol	2016
27149616	Exploiting Genetic Interference for Antiviral Therapy.	PLoS Genet	2016
27235396	The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7.	J Biol Chem	2016
27467384	Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels.	PLoS One	2016
25563937	Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting.	Lab Chip	2015
26488303	The Low Noise Limit in Gene Expression.	PLoS One	2015
26611210	A minimal fate-selection switch.	Curr Opin Cell Biol	2015
25723173	An evolutionary role for HIV latency in enhancing viral transmission.	Cell	2015
25723172	A hardwired HIV latency program.	Cell	2015
24448925	Acoustic focusing with engineered node locations for high-performance microfluidic particle separation.	Analyst	2014
25201951	Stochastic variability in HIV affects viral eradication.	Proc Natl Acad Sci U S A	2014
25017994	The case for transmissible antivirals to control population-wide infectious disease.	Trends Biotechnol	2014
24903562	Screening for noise in gene expression identifies drug synergies.	Science	2014
24586204	Fifteen years later: hard and soft selection sweeps confirm a large population number for HIV in vivo.	PLoS Genet	2014
23221552	Design requirements for interfering particles to maintain coadaptive stability with HIV-1.	J Virol	2013
24243007	Stochastic fate selection in HIV-infected patients.	Cell	2013
23943740	Reply to "Coadaptive stability of interfering particles with HIV-1 when there is an evolutionary conflict".	J Virol	2013
23389931	Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies.	Clin Vaccine Immunol	2013
23255218	BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.	Cell Cycle	2013
22929617	Dynamics of protein noise can distinguish between alternate sources of gene-expression variability.	Mol Syst Biol	2012
23260143	An endogenous accelerator for viral gene expression confers a fitness advantage.	Cell	2012
22976503	Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes.	Lab Chip	2012
23064634	Transcriptional burst frequency and burst size are equally modulated across the human genome.	Proc Natl Acad Sci U S A	2012
21167940	Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise.	Methods	2011
21601105	Lentiviral vectors to study stochastic noise in gene expression.	Methods Enzymol	2011
21483468	Autonomous targeting of infectious superspreaders using engineered transmissible therapies.	PLoS Comput Biol	2011
20409455	Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression.	Biophys J	2010

1 - 50 of 60

Parinaz Fozouni

Gladstone Institute of Virology, Gladstone Institutes

Career Start Year 2017

Number of shared co-authors 5

David Sachs

Icahn School of Medicine at Mount Sinai

Career Start Year 2013

Number of shared co-authors 3

Jessica Sook Yuin Ho

Icahn School of Medicine at Mount Sinai, Duke-NUS Medical School

Career Start Year 2012

Number of shared co-authors 2

Daniel I S Rosenbloom

Merck & Co. Inc.

Career Start Year 2011

Number of shared co-authors 3

Jo??o I Mamede

Rush University Medical Center

Career Start Year 2011

Number of shared co-authors 1

David van Dijk

Yale School of Medicine, Yale University

Career Start Year 2010

Number of shared co-authors 0

Chi N Chan

Vaccine & Gene Therapy Institute, Oregon Health & Science University

Career Start Year 2010

Number of shared co-authors 0

Judd F Hultquist

Northwestern University Feinberg School of Medicine

Career Start Year 2008

Number of shared co-authors 9

Suzannah J Rihn

MRC-University of Glasgow Centre for Virus Research, University of Glasgow

Career Start Year 2008

Number of shared co-authors 4

Will Dampier

Drexel University College of Medicine

Career Start Year 2007

Number of shared co-authors 0

Fabio Zanini

Stanford University

Career Start Year 2006

Number of shared co-authors 3

Lara Manganaro

National Institute of Molecular Genetics, "Fondazione Romeo ed Enrica Invernizzi"

Career Start Year 2005

Number of shared co-authors 4

Ivan Marazzi

Center for Epigenetics and Metabolism, University of California irvine

Career Start Year 2004

Number of shared co-authors 4

Pavitra Roychoudhury

Fred Hutchinson Cancer Center

Career Start Year 2004

Number of shared co-authors 4

Nolwenn Jouvenet

CNRS UMR9, Institut Pasteur, Universite de Paris Cite

Career Start Year 2003

Number of shared co-authors 4

Benjamin D Greenbaum

Memorial Sloan Kettering Cancer Center

Career Start Year 2003

Number of shared co-authors 3

Priya S Shah

University of California davis

Career Start Year 2002

Number of shared co-authors 8

Benjamin R tenOever

NYU Grossman School of Medicine

Career Start Year 2001

Number of shared co-authors 6

Marco Vignuzzi

Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)

Career Start Year 2001

Number of shared co-authors 6

Edward P Browne

University of North Carolina at Chapel Hill

Career Start Year 2000

Number of shared co-authors 0

Renate K??nig

Paul-Ehrlich-Institut

Career Start Year 1998

Number of shared co-authors 2

Viviana Simon

Icahn School of Medicine at Mount Sinai

Career Start Year 1997

Number of shared co-authors 7

Greg J Towers

University College London

Career Start Year 1995

Number of shared co-authors 3

Paul D Bieniasz

The Rockefeller University

Career Start Year 1993

Number of shared co-authors 1

Olivier Schwartz

Institut Pasteur, Universite Paris Cite, CNRS UMR9

Career Start Year 1987

Number of shared co-authors 7

Mohan Somasundaran

University of Massachusetts Chan Medical School

Career Start Year 1985

Number of shared co-authors 1

Frederic D Bushman

Perelman School of Medicine, University of Pennsylvania

Career Start Year 1983

Number of shared co-authors 6

Michael Emerman

Fred Hutchinson Cancer Center

Career Start Year 1982

Number of shared co-authors 8

Raul Andino

University of California san francisco

Career Start Year 1981

Number of shared co-authors 6

Ronald Swanstrom

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill

Career Start Year 1972

Number of shared co-authors 2

row(s) 1 - 30 of 30

Ravi V Desai

Gladstone Institutes

Co-authored papers 4

Melanie Ott

Gladstone Institute of Virology

Co-authored papers 3

Adam P Arkin

Lawrence Berkeley National Laboratory

Co-authored papers 2

Matt Thomson

California Institute of Technology

Co-authored papers 2

Robert F Siliciano

Johns Hopkins University School of Medicine

Co-authored papers 2

David V Schaffer

University of California berkeley

Co-authored papers 2

Daniela Boehm

University College Dublin

Co-authored papers 2

John C Burnett

Mayo Clinic

Co-authored papers 2

Jonathon M Muncie

Gladstone Institutes

Co-authored papers 1

Sara Pagans

University of Girona

Co-authored papers 1

Sharon R Lewin

The University of Melbourne at the Peter Doherty Institute for Infection and Immunity

Co-authored papers 1

Marc K Hellerstein

University of California berkeley

Co-authored papers 1

William J Britt

Heersink School of Medicine, University of Alabama at Birmingham

Co-authored papers 1

Jiewei Xu

Quantitative Biosciences Institute (QBI), University of California san francisco

Co-authored papers 1

Andrea Gramatica

Gladstone Institute of Virology, Gladstone Institutes

Co-authored papers 1

Ruth H??ttenhain

Quantitative Biosciences Institute (QBI), University of California san francisco

Co-authored papers 1

Kevin M Hu

Gladstone Institutes

Co-authored papers 1

Benjamin J Polacco

Gladstone Institutes

Co-authored papers 1

Davey M Smith

University of California San Diego

Co-authored papers 1

James E Bradner

Co-authored papers 1

Holly Ramage

Sidney Kimmel Medical College, Thomas Jefferson University

Co-authored papers 1

Robert A Coleman

Co-authored papers 1

Austin Hsu

Gladstone Institutes

Co-authored papers 1

Thomas A Packard

J. David Gladstone Institutesgrid.249878.8

Co-authored papers 1

Kavitha S Rao

Gladstone Institutes

Co-authored papers 1

Sarah A B Winchester

Gladstone Institutes

Co-authored papers 1

Nilanjana Chatterjee

Chittaranjan National Cancer Institute

Co-authored papers 1

Benoit G Bruneau

Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes

Co-authored papers 1

Warner C Greene

Gladstone Institute of Virology, USA University of California san francisco

Co-authored papers 1

Jeffrey J Saucerman

University of Virginia

Co-authored papers 1

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators