Author details

Full Name

John E Hokanson

Affiliation

ORCID

Career Start Year

1986

Papers

250

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
37770635	Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.	Nat Genet	2023
37709864	Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.	Nat Genet	2023
37417779	Mendelian randomization study of diabetes and dementia in the Million Veteran Program.	Alzheimers Dement	2023
37413999	Deep Learning Integration of Chest Computed Tomography Imaging and Gene Expression Identifies Novel Aspects of COPD.	Chronic Obstr Pulm Dis	2023
37241208	Longitudinal Assessment of Multimorbidity Medication Patterns among Smokers in the COPDGene Cohort.		2023
37160347	Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease.	Am J Epidemiol	2023
37159910	Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment.	Am J Respir Crit Care Med	2023
36945581	Mendelian randomization study of diabetes and dementia in the Million Veteran Program.	medRxiv	2023
36376854	Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD.	Respiratory Research	2022
36041056	A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program.	Diabetes Care	2022
35953715	GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing.	Commun Biol	2022
35927319	Rare genetic variants explain missing heritability in smoking.	Nat Hum Behav	2022
35677475	Identifying Individual Medications Affecting Pulmonary Outcomes When Multiple Medications are Present.	Clinical Epidemiology	2022
35544468	Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models.	PLoS One	2022
35301772	Commentary on Chenoweth et al.: Assessing response to interventions for smoking cessation in diverse populations.	Addiction	2022
35170805	The influence of unmeasured confounding on the MR Steiger approach.	Genet Epidemiol	2022
35040196	Weight gain trajectories and obesity rates in intensive and conventional treatments of type 1 diabetes from the DCCT compared with a control population without diabetes.	Diabetic Medicine	2022
34785234	Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers.	Chest	2022
34592319	Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers.	Chest	2022
34461026	10-Year Follow-Up of Lung Function, Respiratory Symptoms, and Functional Capacity in the COPDGene Study.	Ann Am Thorac Soc	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
33971144	The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers.	Chest	2021
35911870	Increased mortality associated with frequent exacerbations in COPD patients with mild-to-moderate lung function impairment, and smokers with normal spirometry.	Respir Med X	2021
33574123	Respiratory exacerbations are associated with muscle loss in current and former smokers.	Thorax	2021
33563793	Inhaled Medication Use in Smokers With Normal Spirometry.	Respiratory Care	2021
33106845	Genome-Wide Gene-by-Smoking Interaction Study of Chronic Obstructive Pulmonary Disease.	Am J Epidemiol	2021
34010545	Impact of a Medical Diagnosis on Decision to Stop Smoking and Successful Smoking Cessation.	Chronic Obstructive Pulmonary Diseases	2021
34008876	Caution against examining the role of reverse causality in Mendelian Randomization.	Genet Epidemiol	2021
31294817	Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.	Nicotine Tob Res	2020
33326441	Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels.	PLoS ONE	2020
33149694	Co-Morbidity Patterns Identified Using Latent Class Analysis of Medications Predict All-Cause Mortality Independent of Other Known Risk Factors: The COPDGene Study.	Clinical Epidemiology	2020
33144568	Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.	Nat Commun	2020
32803792	Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme.	Genetic Epidemiology	2020
32541258	Impact of self-measured blood pressure monitoring on hypertension management.	Blood Pressure Monitoring	2020
32466134	Association Analysis and Meta-Analysis of Multi-Allelic Variants for Large-Scale Sequence Data.	Genes (Basel)	2020
32368963	Smaller Left Ventricle Size at Noncontrast CT Is Associated with Lower Mortality in COPDGene Participants.	Radiology	2020
32324980	The Association of Multiparity with Lung Function and Chronic Obstructive Pulmonary Disease-Related Phenotypes.	Chronic Obstr Pulm Dis	2020
32324979	Letter to the Editor: Response by Authors.	Chronic Obstr Pulm Dis	2020
32312903	The Use of Mendelian Randomization to Determine the Role of Metabolic Traits on Urinary Albumin-to-Creatinine Ratio.		2020
32198360	Low FVC/TLC in Preserved Ratio Impaired Spirometry (PRISm) is associated with features of and progression to obstructive lung disease.	Sci Rep	2020
32166765	The effects of misspecification of the mediator and outcome in mediation analysis.	Genet Epidemiol	2020
32013794	Five-year Progression of Emphysema and Air Trapping at CT in Smokers with and Those without Chronic Obstructive Pulmonary Disease: Results from the COPDGene Study.	Radiology	2020
31887283	Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study.	Chest	2020
31295146	Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.	Journal of Clinical Investigation	2019
31189730	Turning subtypes into disease axes to improve prediction of COPD progression.	Thorax	2019
31181416	Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: An evaluation in the COPDGene cohort.	Atherosclerosis	2019
30913229	Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups.	PLoS ONE	2019
30908940	Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.	Am J Respir Crit Care Med	2019
30804560	New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.	Nat Genet	2019