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Author Details

Jay W Fox
University of Virginia
1977
192
60
PMIDPaper TitleJournal TitlePublished Year
37205636Periostin+ Stromal Cells Guide Lymphovascular Invasion by Cancer Cells.Cancer Res2023
36977099Mapping the Immune Cell Microenvironment with Spatial Profiling in Muscle Tissue Injected with the Venom of <i>Daboia russelii</i>.Toxins (Basel)2023
36287926Longitudinal Metabolomics and Lipidomics Analyses Reveal Alterations Associated with Envenoming by <i>Bothrops asper</i> and <i>Daboia russelii</i> in an Experimental Murine Model.Toxins (Basel)2022
36072339Editorial: Tumor microenvironment (TME) and tumor immune microenvironment (TIME): New perspectives for prognosis and therapy.Front Cell Dev Biol2022
34186243A Reductionist Approach Using Primary and Metastatic Cell-Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis.Mol Cell Proteomics2021
33918925Report of the 1st International Electronic Conference on Toxins (IECT2021), 16-31 January 2021.Toxins (Basel)2021
34822585Observation of <i>Bothrops atrox</i> Snake Envenoming Blister Formation from Five Patients: Pathophysiological Insights.Toxins (Basel)2021
32781076Analysis of wound exudates reveals differences in the patterns of tissue damage and inflammation induced by the venoms of Daboia russelii and Bothrops asper in mice.Toxicon2020
32906814Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth.Biomolecules2020
30670719The neurotoxic secreted phospholipase A<sub>2</sub> from the Vipera a. ammodytes venom targets cytochrome c oxidase in neuronal mitochondria.Sci Rep2019
31052189Proteomic Analysis of Human Blister Fluids Following Envenomation by Three Snake Species in India: Differential Markers for Venom Mechanisms of Action.Toxins (Basel)2019
29351197Announcing the 2018 Toxins Travel Awards for Post-Doctoral Fellows.Toxins (Basel)2018
30185791Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer.Nat Commun2018
30348024Metalloproteinases in disease: identification of biomarkers of tissue damage through proteomics.Expert Rev Proteomics2018
30382131Systemic vascular leakage induced in mice by Russell's viper venom from Pakistan.Sci Rep2018
29698755Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms.Toxicon2018
29415440Revisiting the Therapeutic Potential of Bothrops jararaca Venom: Screening for Novel Activities Using Connectivity Mapping.Toxins (Basel)2018
27989943Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer.J Proteomics2017
28275208Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez.Toxins (Basel)2017
27035343Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis.PLoS Negl Trop Dis2016
27782073A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming.Toxins (Basel)2016
27886127Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway.Toxins (Basel)2016
27165799CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.mBio2016
26941108Proteomic identification of gender molecular markers in Bothrops jararaca venom.J Proteomics2016
26031306Disintegrins from snake venoms and their applications in cancer research and therapy.Curr Protein Pept Sci2015
26540631Integrative analysis to select cancer candidate biomarkers to targeted validation.Oncotarget2015
25909592Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage.PLoS Negl Trop Dis2015
24762651Proteomic analysis of cattle tick Rhipicephalus (Boophilus) microplus saliva: a comparison between partially and fully engorged females.PLoS One2014
25244421Host response to human breast Invasive Ductal Carcinoma (IDC) as observed by changes in the stromal proteome.J Proteome Res2014
23010165A brief review of the scientific history of several lesser-known snake venom proteins: l-amino acid oxidases, hyaluronidases and phosphodiesterases.Toxicon2013
23602926Connectivity maps for biosimilar drug discovery in venoms: the case of Gila monster venom and the anti-diabetes drug Byetta®.Toxicon2013
23563204Proteomic anatomy of human skin.J Proteomics2013
22995211Milestones and future prospects in snake venom research.Toxicon2013
21939285Hemorrhagic activity of HF3, a snake venom metalloproteinase: insights from the proteomic analysis of mouse skin and blood plasma.J Proteome Res2012
22960448Gene expression of inflammatory mediators induced by jararhagin on endothelial cells.Toxicon2012
22905270Novel processed form of syndecan-1 shed from SCC-9 cells plays a role in cell migration.PLoS One2012
22623999Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis.PLoS One2012
22622419Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo.J Invest Dermatol2012
22282019Mass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cells.J Proteomics2012
22004524Efficacy of IgG and F(ab')2 antivenoms to neutralize snake venom-induced local tissue damage as assessed by the proteomic analysis of wound exudate.J Proteome Res2012
21156218High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry.J Proteomics2011
22194303Phosphorylation sites in the cerebral cavernous malformations complex.J Cell Sci2011
22174764Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases.PLoS One2011
21863142Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.Front Microbiol2011
21928397Bothrops jararaca venom proteome rearrangement upon neonate to adult transition.Proteomics2011
21306181Proteomics of wound exudate in snake venom-induced pathology: search for biomarkers to assess tissue damage and therapeutic success.J Proteome Res2011
21447411Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases.J Proteomics2011
19699224Tissue pathology induced by snake venoms: how to understand a complex pattern of alterations from a systems biology perspective?Toxicon2010
20666496Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds.J Proteome Res2010
20664911New insights into the structural elements involved in the skin haemorrhage induced by snake venom metalloproteinases.Thromb Haemost2010
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Collaborators

Nicholas E Sherman
University of Virginia
Co-authored papers 24
John T Parsons
The School of Medicine, University of Virginia
Co-authored papers 4
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 3
Thomas A E Platts-Mills
University of Virginia
Co-authored papers 3
Steven L Gonias
University of California san francisco
Co-authored papers 2
Donald F Hunt
University of Virginia
Co-authored papers 2
Gregory A Buck
Virginia Commonwealth University.
Co-authored papers 2
Pablo R Grigera
Instituto de Ciencia y Tecnologia Dr. Cesar Milstein
Co-authored papers 2
Mark W Mayhew
University of Virginia
Co-authored papers 2
Peter W Heymann
University of Virginia
Co-authored papers 2
Jeffrey Shabanowitz
University of Virginia
Co-authored papers 2
Alan Rick Horwitz
Allen Institute for Cell Science
Co-authored papers 2
Gabriela Vaz Meirelles
Co-authored papers 2
Mark H Ginsberg
University of California
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Kristina Nelson
Virginia Commonwealth University
Co-authored papers 2
Gilberto B Domont
Institute of Chemistry, Federal University of Rio de Janeiro
Co-authored papers 2
Martha Gunthorpe
University of California San Francisco
Co-authored papers 2
John D Shaughnessy
Co-authored papers 1
Celeste Ptak
Co-authored papers 1
Kathryn S Lilley
University of Cambridge
Co-authored papers 1
Jae K Lee
Co-authored papers 1
Mykola Kovalenko
Co-authored papers 1
Sabrina Daniela da Silva
Jewish General Hospital
Co-authored papers 1
Chad V Pecot
University of North Carolina at Chapel Hill
Co-authored papers 1
Catharine Cowan
Virginia-Maryland College of Veterinary Medicine, Virginia Tech
Co-authored papers 1
Jaewon Han
University of California
Co-authored papers 1
Stephen J P Pratt
University of Maryland School of Medicine
Co-authored papers 1
Jason A Papin
University of Virginia
Co-authored papers 1
Joy M Polefrone
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Robert W Tilghman
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Release 1.2