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Author Details

Brett M Stevens
University of Colorado School of Medicine
2008
42
23
PMIDPaper TitleJournal TitlePublished Year
37358260A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy.Cancer Discov2023
37873284Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.bioRxiv2023
37051756Higher-dose venetoclax with measurable residual disease-guided azacitidine discontinuation in newly diagnosed acute myeloid leukemia.Haematologica2023
37110126Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2.Metabolites2023
34525179The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.Blood2022
36194842Machine Learning-Based Exploratory Clinical Decision Support for Newly Diagnosed Patients With Acute Myeloid Leukemia Treated With 7 + 3 Type Chemotherapy or Venetoclax/Azacitidine.JCO Clin Cancer Inform2022
33155727MDS-associated SF3B1 mutations enhance proinflammatory gene expression in patient blast cells.J Leukoc Biol2021
33857288PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.J Exp Med2021
34610123Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia.Blood Adv2021
33028621The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG.Cancer Discov2021
33109736Exploiting Protein Translation Dependence in Multiple Myeloma with Omacetaxine-Based Therapy.Clin Cancer Res2021
31101752Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.Haematologica2020
33884374Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells.Nat Cancer2020
31974170Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.Cancer Discov2020
33437968Enriching for human acute myeloid leukemia stem cells using reactive oxygen species-based cell sorting.STAR Protoc2020
32822582Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.Cell Stem Cell2020
32841218ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes.JCI Insight2020
32311014Measurement of ex vivo resistance to proteasome inhibitors, IMiDs, and daratumumab during multiple myeloma progression.Blood Adv2020
30753831Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2019
31648312Real-world experience of venetoclax with azacitidine for untreated patients with acute myeloid leukemia.Blood Adv2019
31101624Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.Blood2019
31009835Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia: Clinical results and predictive modeling using computational analysis.Leuk Res2019
30943405The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.Cell Rep2019
30852438Low ferroportin expression in AML is correlated with good risk cytogenetics, improved outcomes and increased sensitivity to chemotherapy.Leuk Res2019
31136781CD123 CAR T cells for the treatment of myelodysplastic syndrome.Exp Hematol2019
30420752Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.Nat Med2018
29910151AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.Cell Stem Cell2018
30209285Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes.Nat Commun2018
30270124Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.Cancer Cell2018
30423294Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2018
26927674MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.J Clin Invest2016
26389776Clonality of neutrophilia associated with plasma cell neoplasms: report of a SETBP1 mutation and analysis of a single institution series.Leuk Lymphoma2016
27888238Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.J Biol Chem2016
27421961Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.Blood2016
27573247Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.J Biol Chem2016
27374788Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.Cell Stem Cell2016
25547679Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.Clin Cancer Res2015
25481740Redox biology in normal cells and cancer: restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment.Free Radic Biol Med2015
24458840Cool-1-mediated inhibition of c-Cbl modulates multiple critical properties of glioblastomas, including the ability to generate tumors in vivo.Stem Cells2014
23606532Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells.EMBO Mol Med2013
18245245Bacterial community structure of acid-impacted lakes: what controls diversity?Appl Environ Microbiol2008
18755985The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene.Blood2008
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Collaborators

Veronica Clavijo Jordan
Harvard Medical School
Co-authored papers 37
Daniel A Pollyea
University of Colorado Division of Hematology
Co-authored papers 26
Shanshan Pei
Zhejiang University Medical Center
Co-authored papers 21
Clayton A Smith
University of Colorado, Aurora CO.
Co-authored papers 19
Mohammad Minhajuddin
University of Colorado School of Medicine
Co-authored papers 17
Amanda Winters
University of Colorado School of Medicine
Co-authored papers 14
Courtney L Jones
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 14
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 14
Biniam Adane
The Broad Institute of MIT and Harvard
Co-authored papers 10
Haobin Ye
Institute of Metabolism & Integrative Biology, Fudan University
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Maria Amaya
University of Colorado School of Medicine
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Diana Abbott
Center for Innovative Design and Analysis, University of Colorado, Aurora CO.
Co-authored papers 9
Rachel Culp-Hill
University of Colorado Anschutz Medical Campus
Co-authored papers 8
Travis Nemkov
University of Colorado Anschutz Medical Campus
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Anna Krug
University of Colorado School of Medicine
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James DeGregori
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Anagha Inguva
University of Colorado School of Medicine
Co-authored papers 6
Maura Gasparetto
University of Colorado School of Medicine
Co-authored papers 5
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Michael W Becker
James P. Wilmot Cancer Institute, University of Rochester Medical Center Rochester
Co-authored papers 4
Mark Noble
University of Rochester Medical Center
Co-authored papers 3
Vadym Zaberezhnyy
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Subhajyoti De
Co-authored papers 2
Fabia Gamboni
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Kirk C Hansen
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Co-authored papers 2
Aik Choon Tan
Huntsman Cancer Institute, The University of Utah
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Christopher Y Park
NYU Robert I. Grossman School of Medicine
Co-authored papers 1
Sarah Gehrke
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Co-authored papers 1
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Release 1.2