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Author Details

Elizabeth R Lawlor
Seattle Children's Research Institute
1996
82
33
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36658218Oncogenic role for an EWS-FLI1 suppressor.Nat Cell Biol2023
37471463Cancer-Associated Fibroblast-Like Tumor Cells Remodel the Ewing Sarcoma Tumor Microenvironment.Clin Cancer Res2023
37090655Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment.bioRxiv2023
37129912β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.Cancer Res2023
36658218Oncogenic role for an EWS-FLI1 suppressor.Nat Cell Biol2023
37090655Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment.bioRxiv2023
37129912β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.Cancer Res2023
37471463Cancer-Associated Fibroblast-Like Tumor Cells Remodel the Ewing Sarcoma Tumor Microenvironment.Clin Cancer Res2023
34997546Single-cell RNA profiling identifies diverse cellular responses to EWSR1/FLI1 downregulation in Ewing sarcoma cells.Cell Oncol (Dordr)2022
35653119EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.Clin Cancer Res2022
36276057Amino acid metabolism in primary bone sarcomas.Front Oncol2022
35616289Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy.ACS Nano2022
35863108Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
36505823The importance of fusion protein activity in Ewing sarcoma and the cell intrinsic and extrinsic factors that regulate it: A review.Front Oncol2022
34997546Single-cell RNA profiling identifies diverse cellular responses to EWSR1/FLI1 downregulation in Ewing sarcoma cells.Cell Oncol (Dordr)2022
35653119EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.Clin Cancer Res2022
35616289Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy.ACS Nano2022
36505823The importance of fusion protein activity in Ewing sarcoma and the cell intrinsic and extrinsic factors that regulate it: A review.Front Oncol2022
36276057Amino acid metabolism in primary bone sarcomas.Front Oncol2022
35863108Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
33741715EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.Mol Cancer Res2021
33741715EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.Mol Cancer Res2021
32544094Wnt/β-catenin-activated Ewing sarcoma cells promote the angiogenic switch.JCI Insight2020
32544094Wnt/β-catenin-activated Ewing sarcoma cells promote the angiogenic switch.JCI Insight2020
30845695Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation.Cancers (Basel)2019
31521948Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma.Neoplasia2019
30845695Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation.Cancers (Basel)2019
31521948Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma.Neoplasia2019
29513652EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
29889191Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts.J Vis Exp2018
30505422Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma.Rare Tumors2018
29997151Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.Mol Cancer Ther2018
29950716Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
29672864Menin regulates the serine biosynthetic pathway in Ewing sarcoma.J Pathol2018
29386236The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling.Mol Cell Proteomics2018
29513652EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
29997151Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.Mol Cancer Ther2018
29889191Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts.J Vis Exp2018
29950716Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
30505422Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma.Rare Tumors2018
29672864Menin regulates the serine biosynthetic pathway in Ewing sarcoma.J Pathol2018
29386236The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling.Mol Cell Proteomics2018
27888797Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.Oncotarget2017
28882943Tissue-directed Implantation Using Ultrasound Visualization for Development of Biologically Relevant Metastatic Tumor Xenografts.In Vivo2017
29238067Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.Cell Death Dis2017
27888797Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.Oncotarget2017
27837031Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.Mol Cancer Ther2017
29238067Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.Cell Death Dis2017
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Collaborators

Stephen L Lessnick
The Ohio State University College of Medicine
Co-authored papers 12
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 9
Timothy J Triche
Center for Epigenetics, Van Andel Research Institute
Co-authored papers 8
Richard B Womer
Co-authored papers 8
Heinrich Kovar
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 8
Jeffrey A Toretsky
Georgetown University Medical Center, Georgetown University
Co-authored papers 7
Uta Dirksen
University Hospital Essen, West German Cancer Center
Co-authored papers 5
Mats Ljungman
Co-authored papers 4
Marc Ladanyi
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Enrique de Alava
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
Co-authored papers 4
Steven G DuBois
Co-authored papers 4
Franck Tirode
Cancer Center of Lyon
Co-authored papers 4
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 4
G??nther H S Richter
Children's Cancer Research Center
Co-authored papers 3
Yidong Chen
The University of Texas Health Science Center at San Antonio
Co-authored papers 3
Richard Gorlick
University of Texas MD Anderson Cancer Center
Co-authored papers 3
Raphaela Schwentner
Children's Cancer Research Institute
Co-authored papers 3
Jozef Ban
Children's Cancer Research Institute
Co-authored papers 3
Patrick J Grohar
Children's Hospital of Philadelphia.
Co-authored papers 3
Neyssa Marina
Stanford University School of Medicine
Co-authored papers 3
Valerie P Opipari
Co-authored papers 3
Costas A Lyssiotis
Co-authored papers 3
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 3
Stefan Burdach
Technische Universitat Munchen
Co-authored papers 3
Katia Scotlandi
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 3
Scott C Borinstein
Vanderbilt University Medical Center
Co-authored papers 3
Aykut Uren
Georgetown University Medical Center
Co-authored papers 2
Maximilian Kauer
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 2
Cristina R Antonescu
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Sandra J Strauss
University College London, Cancer Institute
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Release 1.2