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Author Details

Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
1980
44
29
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33303586Genetic interaction mapping informs integrative structure determination of protein complexes.Science2020
32084337A Quantitative Genetic Interaction Map of HIV Infection.Mol Cell2020
30547882Genetic analysis reveals functions of atypical polyubiquitin chains.Elife2018
30077634Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection.Cell Syst2018
30118682An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.Mol Cell2018
28446597The histone variant H2A.Z promotes splicing of weak introns.Genes Dev2017
28481362Genetic interaction mapping in mammalian cells using CRISPR interference.Nat Methods2017
25544563Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.Mol Cell2015
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
26118995Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.Cell Host Microbe2015
25888283Differential genetic interactions of yeast stress response MAPK pathways.Mol Syst Biol2015
25825871Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast.PLoS Genet2015
25501949Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.Cancer Discov2015
24842270Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations.Bioessays2014
25302077Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.Genome Med2014
25010907Quantitative analysis of triple-mutant genetic interactions.Nat Protoc2014
23407553Quantitative genetic-interaction mapping in mammalian cells.Nat Methods2013
24360963Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.Cell Rep2013
23891562A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.Mol Cell2013
23932120From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.Cell2013
23746449Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.Cell Rep2013
22681890Hierarchical modularity and the evolution of genetic interactomes across species.Mol Cell2012
21185072Phenotypic landscape of a bacterial cell.Cell2011
22190034Global landscape of HIV-human protein complexes.Nature2011
20526336A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.Nat Struct Mol Biol2010
21127252Rewiring of genetic networks in response to DNA damage.Science2010
20959818Epistatic relationships reveal the functional organization of yeast transcription factors.Mol Syst Biol2010
20952395Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.J Biol Chem2010
19269370Functional organization of the S. cerevisiae phosphorylation network.Cell2009
19470761An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics.Mol Cell Biol2009
19176519A complex-based reconstruction of the Saccharomyces cerevisiae interactome.Mol Cell Proteomics2009
19061648A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.Mol Cell2008
19160513High-throughput, quantitative analyses of genetic interactions in E. coli.Nat Methods2008
18818364Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.Science2008
17314980Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.Nature2007
16554755Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.Nature2006
12358429Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD.RNA2002
8710503Characterization of the interaction between the acidic activation domain of VP16 and the RNA polymerase II initiation factor TFIIB.Nucleic Acids Res1996
1646402Reduced binding of TFIID to transcriptionally compromised mutants of VP16.Nature1991
3896517Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases.Cell1985
6326108Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes.Proc Natl Acad Sci U S A1984
6135505Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein.Cancer Res1983
14582161DNA-mediated transfer of an RNA polymerase II gene: reversion of the temperature-sensitive hamster cell cycle mutant TsAF8 by mammalian DNA.Mol Cell Biol1982
7462338Defective RNA polymerase II in the G1 specific temperature sensitive hamster cell mutant TsAF8.J Cell Physiol1980
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Collaborators

University of California San Francisco
Co-authored papers 36
University of California San Francisco
Co-authored papers 12
Miguel Hernandez University of Elche.
Co-authored papers 9
University of California davis
Co-authored papers 8
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 8
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 8
Gladstone Institutes
Co-authored papers 8
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 7
University of California San Francisco
Co-authored papers 7
University of California san francisco
Co-authored papers 6
University College Dublin
Co-authored papers 6
Whitehead Institute for Biomedical Research
Co-authored papers 6
Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes
Co-authored papers 6
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
Co-authored papers 5
EpiCypher Inc.
Co-authored papers 5
University of California San Diego
Co-authored papers 5
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 5
College Street, University of Toronto
Co-authored papers 5
University of California San Francisco
Co-authored papers 5
Institute of Molecular Biosciences, Goethe University Frankfurt
Co-authored papers 4
Texas A&M University School of Medicine
Co-authored papers 4
Princess Maxima Center for Pediatric Oncology
Co-authored papers 4
Boston University School of Medicine, Boston University
Co-authored papers 4
University of California San Francisco
Co-authored papers 4
Albert Einstein College of Medicine
Co-authored papers 3
Brandeis University
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Emory University
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University of California san francisco
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University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 3
Fudan University
Co-authored papers 3