Author details

Full Name

Sylvia E Le DÃ©vÃ©dec

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37710020	Community-developed checklists for publishing images and image analyses.	Nat Methods	2024
37531576	.		2023
35505273	High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitors.	Cell Biology and Toxicology	2023
38015832	A Network-based Transcriptomic Landscape of HepG2 cells Uncovering Causal Gene-Cytotoxicity Interactions Underlying Drug-Induced Liver Injury.		2023
37147730	Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.		2023
36826702	Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia.		2023
37460560	FAIR High Content Screening in Bioimaging.	Sci Data	2023
37379365	Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors.		2023
37356380	Single-cell metabolomics by mass spectrometry: ready for primetime?		2023
34642769	Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.	Archives of Toxicology	2022
36279267	A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A Receptor Using an Electrophilic Covalent Probe.	ACS Chemical Biology	2022
36077517	Hypoxia Triggers TAZ Phosphorylation in Basal A Triple Negative Breast Cancer Cells.	International Journal of Molecular Sciences	2022
36140753	Crosstalk between Hypoxia and Extracellular Matrix in the Tumor Microenvironment in Breast Cancer.	Genes	2022
35422905	Hypocholesterolemic phospholipid transfer protein knockout mice exhibit a normal glucocorticoid response to food deprivation.	American Journal of Translational Research (discontinued)	2022
36139513	Targeting the Heterogeneous Genomic Landscape in Triple-Negative Breast Cancer through Inhibitors of the Transcriptional Machinery.	Cancers	2022
35802572	Model-based translation of DNA damage signaling dynamics across cell types.	PLoS Computational Biology	2022
35677430	Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters.	Frontiers in Pharmacology	2022
35547818	Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction.	Frontiers in Cell and Developmental Biology	2022
36057753	Acute vs. chronic vs. intermittent hypoxia in breast Cancer: a review on its application in in vitro research.	Molecular Biology Reports	2022
35403421	Spatial and Temporal Modulation of Cell Instructive Cues in a Filamentous Supramolecular Biomaterial.	ACS applied materials & interfaces	2022
34448005	Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters.	Mutagenesis	2022
34657378	Preclinical models versus clinical renal ischemia reperfusion injury: A systematic review based on metabolic signatures.	American Journal of Transplantation	2022
34480604	Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages.	Archives of Toxicology	2021
33812964	Circumventing the Crabtree effect in cell culture: A systematic review.	Mitochondrion	2021
33957093	Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury.	Biochem Pharmacol	2021
33790333	Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.	Sci Rep	2021
33769548	Physiologically Relevant Estrogen Receptor Alpha Pathway Reporters for Single-Cell Imaging-Based Carcinogenic Hazard Assessment of Estrogenic Compounds.	Toxicological Sciences	2021
33648524	Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.	J Exp Clin Cancer Res	2021
32781105	Results of an explorative clinical evaluation suggest immediate and persistent post-reperfusion metabolic paralysis drives kidney ischemia reperfusion injury.	Kidney International	2020
31857432	Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFÎ²-Induced Breast Cancer Metastasis.	Clin Cancer Res	2020
32396199	Community standards for open cell migration data.	Gigascience	2020
31358840	Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.	Sci Rep	2019
31893226	Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells.	ACS Central Science	2019
31666932	Splicing regulatory factors in breast cancer hallmarks and disease progression.	Oncotarget	2019
30929299	The direct oral anticoagulants rivaroxaban and dabigatran do not inhibit orthotopic growth and metastasis of human breast cancer in mice.	Journal of Thrombosis and Haemostasis	2019
31278301	Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes.	Nat Commun	2019
30940821	Co-regulated gene expression of splicing factors as drivers of cancer progression.	Sci Rep	2019
31536726	FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells.	Biochemical Pharmacology	2019
28666065	A Red-Light-Activated Ruthenium-Caged NAMPT Inhibitor Remains Phototoxic in Hypoxic Cancer Cells.	Angewandte Chemie - International Edition	2017
25774502	Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.	J Clin Invest	2015
25484346	An open data ecosystem for cell migration research.	Trends Cell Biol	2015
25086087	A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.	Mol Syst Biol	2014
25289886	Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.	PLoS ONE	2014
25415239	Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.	Elife	2014
23792445	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	Oncogene	2014
24518294	Î²1 integrin inhibition elicits a prometastatic switch through the TGFÎ²-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.	Sci Signal	2014
21725361	p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.	Oncogene	2012
22767508	The residence time of focal adhesion kinase (FAK) and paxillin at focal adhesions in renal epithelial cells is determined by adhesion size, strength and life cycle status.	Journal of Cell Science	2012
21748686	Two-photon intravital multicolour imaging to study metastatic behaviour of cancer cells in vivo.	Methods in Molecular Biology	2011
20396956	Two-photon intravital multicolor imaging combined with inducible gene expression to distinguish metastatic behavior of breast cancer cells in vivo.	Molecular Imaging and Biology	2011